CA2125483A1 - Cetylpyridinium chloride and domiphen bromide in organic solvent - Google Patents

Cetylpyridinium chloride and domiphen bromide in organic solvent

Info

Publication number
CA2125483A1
CA2125483A1 CA002125483A CA2125483A CA2125483A1 CA 2125483 A1 CA2125483 A1 CA 2125483A1 CA 002125483 A CA002125483 A CA 002125483A CA 2125483 A CA2125483 A CA 2125483A CA 2125483 A1 CA2125483 A1 CA 2125483A1
Authority
CA
Canada
Prior art keywords
microcapsules
breath
microcapsule
salts
gelatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002125483A
Other languages
English (en)
French (fr)
Inventor
Mary Ann Hunter
Judith H. Stapler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2125483A1 publication Critical patent/CA2125483A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA002125483A 1991-12-11 1992-12-07 Cetylpyridinium chloride and domiphen bromide in organic solvent Abandoned CA2125483A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80543291A 1991-12-11 1991-12-11
US07/805,432 1991-12-11

Publications (1)

Publication Number Publication Date
CA2125483A1 true CA2125483A1 (en) 1993-06-24

Family

ID=25191562

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002125483A Abandoned CA2125483A1 (en) 1991-12-11 1992-12-07 Cetylpyridinium chloride and domiphen bromide in organic solvent

Country Status (7)

Country Link
US (2) US5286496A (enExample)
EP (1) EP0616526A1 (enExample)
CA (1) CA2125483A1 (enExample)
FI (1) FI942765A0 (enExample)
NO (1) NO942170D0 (enExample)
TR (1) TR27527A (enExample)
WO (1) WO1993011754A1 (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370864A (en) * 1993-06-29 1994-12-06 The Procter & Gamble Company Breath protection microcapsules
US5620707A (en) * 1993-06-29 1997-04-15 The Procter & Gamble Company Beadlets for customization of flavor and sweetener in a beverage
ES2187560T3 (es) * 1994-07-25 2003-06-16 Warner Lambert Co Dentifrico antiseptico.
US5616315A (en) * 1994-10-13 1997-04-01 Gillette Canada Inc. Particles including degradable material and anti-microbial agent
WO1996029986A1 (en) * 1995-03-29 1996-10-03 The Procter & Gamble Company Antitussive microcapsules
US5631024A (en) * 1995-05-22 1997-05-20 Enviroquest, Ltd. Medicaments for beneficial insects and method
CN1225230C (zh) * 1995-06-07 2005-11-02 南方生物系统公司 高粘度液体受控输送体系
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
CN1044668C (zh) * 1996-07-10 1999-08-18 高谦 一种植物油脂组合物
DE19652257A1 (de) * 1996-12-16 1998-06-18 Lohmann Therapie Syst Lts Einzeln dosierte, bei Kontakt mit Flüssigkeit schnell zerfallende, wirkstoff- und insbesondere aromastoffhaltige, folienförmige Darreichnungsform
RU2202220C2 (ru) * 1997-12-30 2003-04-20 Вм. Ригли Дж. Компани Способ получения готовой жевательной резинки, содержащей антибактериальный агент с контролируемым высвобождением (варианты), и готовая жевательная резинка
US6592912B1 (en) 1997-12-30 2003-07-15 Wm. Wrigley Jr. Company Method of controlling release of antimicrobial agents from chewing gum and gum produced thereby
US6174514B1 (en) * 1999-04-12 2001-01-16 Fuisz Technologies Ltd. Breath Freshening chewing gum with encapsulations
US6436369B2 (en) * 1998-12-17 2002-08-20 Wm. Wrigley Jr. Company Anti-plaque emulsions and products containing same
DE19905585A1 (de) * 1999-02-11 2000-08-17 Beiersdorf Ag Verwendung von quaternären Ammoniumverbindungen als Antitranspirantien
GB9917547D0 (en) * 1999-07-26 1999-09-29 Orafresh Limited Dentifrice compositions
US20010043941A1 (en) * 2000-03-23 2001-11-22 Hiep Huatan Oral formulations of medicaments
WO2002002745A2 (en) * 2000-07-05 2002-01-10 Islet Technology, Inc. Method and system for consistent and effective encapsulation of biological material
US6565873B1 (en) * 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
US6589562B1 (en) * 2000-10-25 2003-07-08 Salvona L.L.C. Multicomponent biodegradable bioadhesive controlled release system for oral care products
JP2002277816A (ja) * 2001-03-21 2002-09-25 Minolta Co Ltd 映像表示装置
AU2002253484B2 (en) * 2001-06-11 2006-11-16 Warner-Lambert Company Llc Breath protection microcapsules
US20030228368A1 (en) * 2001-09-28 2003-12-11 David Wynn Edible solid composition and dosage form
FR2832632B1 (fr) 2001-11-26 2004-04-23 Mane Fils V Capsule a solubilisation et liberation du contenu rapides
US20030118658A1 (en) * 2001-12-21 2003-06-26 Trogolo Jeffrey A. High aspect ratio encapsulated inorganic antimicrobial additive for controlled release
US7357949B2 (en) * 2001-12-21 2008-04-15 Agion Technologies Inc. Encapsulated inorganic antimicrobial additive for controlled release
US6579513B1 (en) 2002-01-03 2003-06-17 Playtex Products, Inc. Hygiene mouthspray composition
US20030228336A1 (en) * 2002-06-07 2003-12-11 Carla Gervasio Cosmetic compositions and container therefor
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
AU2003299659A1 (en) * 2002-12-13 2004-07-09 Durect Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
EP1732680B1 (en) * 2004-02-17 2008-07-30 Symrise GmbH & Co. KG Coated sherical seamless filled capsules
DK2767292T3 (en) 2004-09-17 2016-12-19 Durect Corp RENEWABLE local anesthetic COMPOSITION CONTAINING SAIB
DE602006016561D1 (de) * 2005-03-04 2010-10-14 Wrigley W M Jun Co Gefüllte geleebonbons
US20090191510A1 (en) * 2005-06-22 2009-07-30 Cao Group, Inc. Periodontal treatment employing applied ultrasonic energy
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
EP1917003A1 (en) * 2005-08-16 2008-05-07 Symrise GmbH & Co. KG Seamless coated spherical filled capsules
US20070053972A1 (en) * 2005-09-08 2007-03-08 Cadbury Adams Usa Llc. Gelatin capsules containing actives
ITMI20052342A1 (it) * 2005-12-06 2007-06-07 Perfetti Van Melle Spa Formulazioni per l'igiene orale in forma di capsule
CA2642954A1 (en) * 2006-02-28 2007-09-07 Appleton Papers Inc. Benefit agent containing delivery particle
DE602007011272D1 (de) * 2006-08-01 2011-01-27 Procter & Gamble Pflegemittel mit freisetzungspartikel
PL2117521T3 (pl) 2006-11-03 2012-11-30 Durect Corp Transdermalne systemy dostarczania zawierające bupiwakainę
MX2009005390A (es) * 2006-11-22 2009-06-02 Procter & Gamble Particula de suministro que contiene agentes beneficos.
US20080152677A1 (en) * 2006-12-20 2008-06-26 Roberto Colle Oral hygiene formulations in the form of capsules
JP2010516863A (ja) * 2007-02-15 2010-05-20 ザ プロクター アンド ギャンブル カンパニー 有益剤送達組成物
JP5978480B2 (ja) * 2007-06-11 2016-08-24 エンカプシス エルエルシー 有益剤含有デリバリー粒子
EP2219622A1 (en) 2007-12-06 2010-08-25 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
WO2011075556A1 (en) * 2009-12-18 2011-06-23 The Procter & Gamble Company Composition comprising encapsulates, and process for making them
US20110271968A1 (en) * 2010-05-07 2011-11-10 Carolyn Rierson Carpenter Filtered Cigarette With Modifiable Sensory Characteristics
AU2014233453A1 (en) 2013-03-15 2015-10-01 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
CN109475505A (zh) 2016-07-06 2019-03-15 度瑞公司 具有药物组成物、屏障层及药物层的口服剂型
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
WO2021167845A1 (en) 2020-02-18 2021-08-26 Sunstar Americas, Inc. Oral care composition
KR20230145053A (ko) 2021-01-12 2023-10-17 듀렉트 코퍼레이션 지속 방출 약물 전달 시스템 및 관련 방법

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2311923A (en) * 1939-06-08 1943-02-23 Iodent Chemical Company Cough drop
US2446792A (en) * 1943-08-28 1948-08-10 Wm S Merrell Co Substituted pyridinium and piperidinium compounds
GB1060258A (en) * 1964-12-05 1967-03-01 Sandoz Products Ltd Improvements in or relating to pharmaceutical pastilles
US3431208A (en) * 1965-11-17 1969-03-04 Schering Corp Denture spray
FR2051483A1 (en) * 1969-05-19 1971-04-09 Midy Centre Rech M Proteolytic enzymes for treating throat - infections
US3959457A (en) * 1970-06-05 1976-05-25 Temple University Microparticulate material and method of making such material
US3832460A (en) * 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
JPS518876B2 (enExample) * 1972-10-03 1976-03-22
US3911099A (en) * 1974-01-23 1975-10-07 Defoney Brenman Mayes & Baron Long-acting articles for oral delivery and process
US4039653A (en) * 1974-01-23 1977-08-02 Defoney, Brenman, Mayes & Baron Long-acting articles for oral delivery and process
US3957964A (en) * 1974-01-30 1976-05-18 Colgate-Palmolive Company Dentifrice containing encapsulated flavoring
US4071614A (en) * 1975-06-03 1978-01-31 Colgate Palmolive Company Dentifrice containing encapsulated flavoring
NL180807C (nl) * 1975-12-26 1987-05-04 Morishita Jintan Co Inrichting voor het vervaardigen van naadloze, met materiaal gevulde capsules.
DE2712161C2 (de) * 1977-03-19 1983-01-05 Blendax-Werke R. Schneider Gmbh & Co, 6500 Mainz Zahn- und Mundpflegemittel
US4196189A (en) * 1977-03-19 1980-04-01 Blendax-Werke R. Schneider Dental and oral hygiene preparations
US4292028A (en) * 1979-07-13 1981-09-29 Arthur Barr Cosmetic breath freshener and palate coolant composition and method of use
US4260596A (en) * 1979-08-13 1981-04-07 Bristol-Myers Company Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same
US4409202A (en) * 1980-04-07 1983-10-11 Nabisco Brands, Inc. Breath freshener composition and method
US4312889A (en) * 1980-04-30 1982-01-26 Design & Funding, Inc. Liquid carrier concentrate for pre-loaded cup
US4329333A (en) * 1980-11-24 1982-05-11 Arthur Barr Method for the oral treatment of dogs and other animals
US4481157A (en) * 1982-04-27 1984-11-06 Morishita Jintan Co., Ltd. Method and apparatus for production of microcapsules
US4597959A (en) * 1982-04-30 1986-07-01 Arthur Barr Sustained release breath freshener, mouth and palate coolant wafer composition and method of use
JPS5953410A (ja) * 1982-09-20 1984-03-28 Fujisawa Pharmaceut Co Ltd 新型ソフトカプセル剤
US4422985A (en) * 1982-09-24 1983-12-27 Morishita Jintan Co., Ltd. Method and apparatus for encapsulation of a liquid or meltable solid material
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
FR2570604B1 (fr) * 1984-09-25 1988-12-30 Pharmedis Sa Nouveau procede d'encapsulation de substances volatiles et les compositions phyto-aromatiques ainsi obtenues
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4765984A (en) * 1986-01-22 1988-08-23 Colgate-Palmolive Company Stable single unit dose oral product
US4710384A (en) * 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
US4762719A (en) * 1986-08-07 1988-08-09 Mark Forester Powder filled cough product
US4847090A (en) * 1986-11-07 1989-07-11 Warner-Lambert Company Confection product and method for making same
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
FR2608456B1 (fr) * 1986-12-18 1993-06-18 Mero Rousselot Satia Microcapsules a base de gelatine et de polysaccharides et leur procede d'obtention
US5004595A (en) * 1986-12-23 1991-04-02 Warner-Lambert Company Multiple encapsulated flavor delivery system and method of preparation
US5043154A (en) * 1987-01-30 1991-08-27 Colgate-Palmolive Co. Antibacterial, antiplaque, anticalculus oral composition
US4857335A (en) * 1987-03-27 1989-08-15 Lim Technology Laboratories, Inc. Liquid controlled release formulations and method of producing same via multiple emulsion process
US4906488A (en) * 1987-05-01 1990-03-06 Arcade, Inc. Modification of permeant
US4797234A (en) * 1987-06-19 1989-01-10 Temple University Production of sustained release composition from salt-form reactants
JPH0725649B2 (ja) * 1987-10-12 1995-03-22 而至歯科工業株式会社 消毒剤含有アルギン酸印象材
JP2540892B2 (ja) * 1987-12-11 1996-10-09 ライオン株式会社 口腔用組成物
US5061106A (en) * 1988-03-08 1991-10-29 Colgate-Palmolive Company Toothbrush with slow release of disinfectant and antibacterial agents and method of manufacturing the same
JPH01231934A (ja) * 1988-03-10 1989-09-18 Lion Corp マイクロカプセルの製造方法
US5164195A (en) * 1988-04-19 1992-11-17 Southwest Research Institute Method of oral delivery with an adherent controlled-release salt sensitive capsule
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
AU618096B2 (en) * 1988-04-19 1991-12-12 Southwest Research Institute Controlled release of active ingredients from capsules having a salt sensitive shell material
US4861268A (en) * 1988-06-13 1989-08-29 Transpharm Group Tooth-anchored beneficial agent delivery device
US4917892A (en) * 1988-06-28 1990-04-17 Temple University Encapsulated topical delivery system
EP0464023A4 (en) * 1988-09-06 1992-04-08 Encapsulation Systems, Inc Realease assist microcapsules
FR2643261A1 (fr) * 1989-02-22 1990-08-24 Tonelli Jean Charles Perfectionnement aux dentifrices
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
WO1990015592A1 (en) * 1989-06-12 1990-12-27 Patrick John Shanahan Anti-plaque dentifrice
US5098725A (en) * 1989-06-30 1992-03-24 Bio-Dar, Ltd. Heat stabilized flavoring agents coated with hydrogenated castor oil
US5013557A (en) * 1989-10-03 1991-05-07 Warner-Lambert Company Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same
FR2652741B1 (fr) * 1989-10-10 1994-03-04 Laboratoires Care System Composition antimicrobienne pour application sur la peau, applications comme deodorant corporel et bactericide cutane.
DK546289D0 (da) * 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
US5008106A (en) * 1989-12-14 1991-04-16 Gaf Chemicals Corporation Method for reducing the microbial content of surfaces with a microbiocidal, anhydrous complex of PVP-H2 O2
US5132117A (en) * 1990-01-11 1992-07-21 Temple University Aqueous core microcapsules and method for their preparation
JPH0684294B2 (ja) * 1990-05-29 1994-10-26 サンスター株式会社 口腔用組成物
US5135747A (en) * 1991-05-17 1992-08-04 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Deodorant/antiperspirant products with fragrance and encapsulated odor counteractant

Also Published As

Publication number Publication date
US5286496A (en) 1994-02-15
FI942765L (fi) 1994-06-10
FI942765A7 (fi) 1994-06-10
WO1993011754A1 (en) 1993-06-24
NO942170D0 (no) 1994-06-10
US5382424A (en) 1995-01-17
NO942170L (enExample) 1994-06-10
EP0616526A1 (en) 1994-09-28
FI942765A0 (fi) 1994-06-10
TR27527A (tr) 1995-06-07

Similar Documents

Publication Publication Date Title
CA2125483A1 (en) Cetylpyridinium chloride and domiphen bromide in organic solvent
US5300305A (en) Breath protection microcapsules
US5370864A (en) Breath protection microcapsules
US4329333A (en) Method for the oral treatment of dogs and other animals
ES2995338T3 (en) Stable microcapsule compositions
AU682489B2 (en) Reduced alcohol mouthwash antiseptic and antiseptic preparations
CA1149747A (en) Toothpaste comprising a copper compound and a silica polishing agent useful for the prevention of the formation of dental plaque
RU2481098C1 (ru) Композиции для ухода за полостью рта, которые увеличивают количество растворимого цинка
RU2697881C2 (ru) Стабилизация пленки оксида цинка в композициях для ухода за полостью рта
CA1155398A (en) Tranexamic compound with folic acid as oral composition
EP2654671B1 (en) Non-aqueous oral care composition containing dental occlusion actives
HUP0202797A2 (hu) Javított stabilitású készítmények
WO2001080823A3 (en) Composition exhibiting enhanced formulation stability and delivery of tropical active ingredients
JP2003500343A (ja) 光に対し安定なサンスクリーン組成物の製造方法
RU2554807C2 (ru) Растворимые пленки, содержащие высокие концентрации неионных поверхностно-активных веществ, таких как полисорбаты, для увеличения высоких нагрузок твердых продуктов
EP1155683B1 (en) Oral composition with an improved teeth whitening effect
US6506368B2 (en) Process for producing blue microcapsules
EP2654672B1 (en) Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier
NZ240508A (en) Oral compositions containing a 2- or 3-(8 to 16c alkyl)-4-hydroxyalkyl morpholine and a salt of a group 2 or transition metal
US6306372B1 (en) Oral hygiene compositions which mask the burn sensation and the astringency of eucalyptol and zinc
SK15362003A3 (sk) Mikrokapsulová kompozícia na antiseptickú ochranu dychu
WO1997016159A1 (en) Enhanced anti-inflammatory oral composition containing h2 receptor antagonist and antimicrobial oils
CA1257842A (en) Antimicrobial lozenges
WO2015138319A1 (en) Oral care compositions comprising microcapsules with effective breakage characteristics
CN101495084B (zh) 口腔护理组合物

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued