CA2101918A1 - Conjugues de polypeptides et de glycopolypeptides avec des polymeres contenant de l'hydrazine - Google Patents

Conjugues de polypeptides et de glycopolypeptides avec des polymeres contenant de l'hydrazine

Info

Publication number
CA2101918A1
CA2101918A1 CA002101918A CA2101918A CA2101918A1 CA 2101918 A1 CA2101918 A1 CA 2101918A1 CA 002101918 A CA002101918 A CA 002101918A CA 2101918 A CA2101918 A CA 2101918A CA 2101918 A1 CA2101918 A1 CA 2101918A1
Authority
CA
Canada
Prior art keywords
macromolecular conjugate
group
glycopolypeptide
polymer
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002101918A
Other languages
English (en)
Inventor
Samuel Zalipsky
Chyi Lee
Sunitha Menon-Rudolph
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enzon Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2101918A1 publication Critical patent/CA2101918A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002101918A 1991-03-18 1992-03-12 Conjugues de polypeptides et de glycopolypeptides avec des polymeres contenant de l'hydrazine Abandoned CA2101918A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67269691A 1991-03-18 1991-03-18
US07/672,696 1991-03-18

Publications (1)

Publication Number Publication Date
CA2101918A1 true CA2101918A1 (fr) 1992-09-19

Family

ID=24699627

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002101918A Abandoned CA2101918A1 (fr) 1991-03-18 1992-03-12 Conjugues de polypeptides et de glycopolypeptides avec des polymeres contenant de l'hydrazine

Country Status (5)

Country Link
EP (1) EP0576589A4 (fr)
JP (1) JPH06506217A (fr)
AU (1) AU1676992A (fr)
CA (1) CA2101918A1 (fr)
WO (1) WO1992016555A1 (fr)

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AU1676992A (en) 1992-10-21
EP0576589A4 (en) 1994-07-27

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