CA2098821C - Benzodioxane derivatives - Google Patents

Benzodioxane derivatives Download PDF

Info

Publication number
CA2098821C
CA2098821C CA002098821A CA2098821A CA2098821C CA 2098821 C CA2098821 C CA 2098821C CA 002098821 A CA002098821 A CA 002098821A CA 2098821 A CA2098821 A CA 2098821A CA 2098821 C CA2098821 C CA 2098821C
Authority
CA
Canada
Prior art keywords
compound
group
ethyl
benzodioxan
ylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002098821A
Other languages
English (en)
French (fr)
Other versions
CA2098821A1 (en
Inventor
Akira Koda
Tatsuo Miyauchi
Yoshitake Kanbe
Hirokazu Hamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of CA2098821A1 publication Critical patent/CA2098821A1/en
Application granted granted Critical
Publication of CA2098821C publication Critical patent/CA2098821C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Light Receiving Elements (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA002098821A 1991-10-22 1992-10-21 Benzodioxane derivatives Expired - Fee Related CA2098821C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP27403691 1991-10-22
JP274036/1991 1991-10-22
JP107570/1992 1992-04-27
JP10757092 1992-04-27
JP278776/1992 1992-10-16
JP04278776A JP3136206B2 (ja) 1991-10-22 1992-10-16 ベンゾジオキサン誘導体
PCT/JP1992/001366 WO1993008182A1 (fr) 1991-10-22 1992-10-21 Derive de benzodioxane

Publications (2)

Publication Number Publication Date
CA2098821A1 CA2098821A1 (en) 1993-04-23
CA2098821C true CA2098821C (en) 2004-01-27

Family

ID=27311013

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002098821A Expired - Fee Related CA2098821C (en) 1991-10-22 1992-10-21 Benzodioxane derivatives

Country Status (12)

Country Link
US (1) US5480905A (enExample)
EP (1) EP0565732B1 (enExample)
JP (1) JP3136206B2 (enExample)
KR (1) KR100217166B1 (enExample)
AT (1) ATE162189T1 (enExample)
AU (1) AU2798692A (enExample)
CA (1) CA2098821C (enExample)
DE (1) DE69224058T2 (enExample)
ES (1) ES2112337T3 (enExample)
SG (1) SG50640A1 (enExample)
TW (1) TW206222B (enExample)
WO (1) WO1993008182A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3235448B2 (ja) * 1995-03-24 2001-12-04 ダイソー株式会社 １，４−ベンゾジオキサン誘導体の製法
EP0870757B1 (en) * 1997-04-10 2002-06-12 Pfizer Inc. Fluoro-substituted adamantane derivatives
US6020503A (en) * 1997-05-12 2000-02-01 Daiso Co., Ltd. Process for producing 1,4-benzodioxane derivatives
JP4604583B2 (ja) * 2004-07-20 2011-01-05 ダイソー株式会社 １−アミド−３−（２−ヒドロキシフェノキシ）−２−プロパノール誘導体、ならびに２−アミドメチル−１，４−ベンゾジオキサン誘導体の製造法
US8552078B2 (en) * 2006-10-17 2013-10-08 Air Products And Chemicals, Inc. Crosslinkers for improving stability of polyurethane foams
US8466296B2 (en) * 2007-03-26 2013-06-18 Ligand Pharmaceuticals Compounds and processes for preparing substituted aminomethyl-2,3,8,9-tetrahydro-7H-1,4-dioxino[2,3-e]indol-8-ones
GB201801130D0 (en) 2018-01-24 2018-03-07 Univ Oxford Innovation Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR241161A1 (es) * 1984-07-30 1991-12-30 Merrelll Dow Pharmaceuticals I "procedimiento para la preparacion de derivados n-aminoalquilen sustituidos de la glutarimida"
US5010078A (en) * 1988-05-24 1991-04-23 American Home Products Corporation Aryl- and heteroaryl piperazinyl carboxamides having central nervous system activity
IL90279A (en) * 1988-05-24 1995-03-30 American Home Prod Piperazinyl carboxamide derivatives, their preparation and pharmaceutical com¦ositions containing them
US5036070A (en) * 1990-06-13 1991-07-30 American Home Products Corporation Polycyclic phenalkyl amines as psychotropic agents
US5126367A (en) * 1991-06-21 1992-06-30 American Home Products Corporation Psychotropic benzodioxan derivatives

Also Published As

Publication number Publication date
DE69224058D1 (de) 1998-02-19
KR100217166B1 (ko) 1999-09-01
DE69224058T2 (de) 1998-10-15
EP0565732B1 (en) 1998-01-14
WO1993008182A1 (fr) 1993-04-29
ES2112337T3 (es) 1998-04-01
EP0565732A4 (enExample) 1994-04-27
EP0565732A1 (en) 1993-10-20
CA2098821A1 (en) 1993-04-23
JPH069613A (ja) 1994-01-18
AU2798692A (en) 1993-05-21
TW206222B (enExample) 1993-05-21
JP3136206B2 (ja) 2001-02-19
SG50640A1 (en) 1998-07-20
ATE162189T1 (de) 1998-01-15
US5480905A (en) 1996-01-02

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