CA2097607A1 - Utilisation de certains derives de glutarimide dans le traitement de la depression et de la manie - Google Patents

Utilisation de certains derives de glutarimide dans le traitement de la depression et de la manie

Info

Publication number
CA2097607A1
CA2097607A1 CA002097607A CA2097607A CA2097607A1 CA 2097607 A1 CA2097607 A1 CA 2097607A1 CA 002097607 A CA002097607 A CA 002097607A CA 2097607 A CA2097607 A CA 2097607A CA 2097607 A1 CA2097607 A1 CA 2097607A1
Authority
CA
Canada
Prior art keywords
alkyl
azaspiro
decane
dione
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002097607A
Other languages
English (en)
Inventor
Marcel Hibert
Maurice W. Gittos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2097607A1 publication Critical patent/CA2097607A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CA002097607A 1990-12-24 1991-12-02 Utilisation de certains derives de glutarimide dans le traitement de la depression et de la manie Abandoned CA2097607A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90403757.9 1990-12-24
EP90403757 1990-12-24

Publications (1)

Publication Number Publication Date
CA2097607A1 true CA2097607A1 (fr) 1992-06-24

Family

ID=8205790

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002097607A Abandoned CA2097607A1 (fr) 1990-12-24 1991-12-02 Utilisation de certains derives de glutarimide dans le traitement de la depression et de la manie

Country Status (7)

Country Link
EP (1) EP0564520A1 (fr)
JP (1) JPH06504279A (fr)
KR (1) KR930702976A (fr)
AU (1) AU9134191A (fr)
CA (1) CA2097607A1 (fr)
HU (1) HU9301856D0 (fr)
WO (1) WO1992011011A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2552929C1 (ru) * 2013-11-14 2015-06-10 Общество С Ограниченной Ответственностью "Фарминтерпрайсез" Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
AR241161A1 (es) * 1984-07-30 1991-12-30 Merrelll Dow Pharmaceuticals I "procedimiento para la preparacion de derivados n-aminoalquilen sustituidos de la glutarimida"
AU583343B2 (en) * 1985-01-23 1989-04-27 Glaxo Group Limited Heterocyclic compounds
US4748182A (en) * 1986-03-05 1988-05-31 Merrell Dow Pharmaceuticals Inc. Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
US4788290A (en) * 1987-12-11 1988-11-29 American Home Products Corporation Serotonergic pyrazine derivatives
DE3831888A1 (de) * 1988-09-20 1990-03-29 Troponwerke Gmbh & Co Kg Arzneimittel zur behandlung von apoplexia cerebri
EP0375819A1 (fr) * 1988-12-20 1990-07-04 Merrell Dow Pharmaceuticals Inc. Dérivés de 1,7'-[imidazo-[1,2-a]pyridin]5'-(6'H)ones

Also Published As

Publication number Publication date
AU9134191A (en) 1992-07-22
HU9301856D0 (en) 1993-09-28
WO1992011011A1 (fr) 1992-07-09
KR930702976A (ko) 1993-11-29
EP0564520A1 (fr) 1993-10-13
JPH06504279A (ja) 1994-05-19

Similar Documents

Publication Publication Date Title
ES2286491T3 (es) Piperidina-ftalazonas sustituidas con pirrolidinadiona, como agentes inhibidores de la pde4.
KR970009588B1 (ko) 헤테로사이클릭 화합물
AU2012219251B2 (en) Compounds and methods for treatment of hypertension
US7026320B2 (en) Serotonergic agents
KR20020069375A (ko) 알파-2-아드레날린성 수용체 길항제로서의 1,3-이치환된피롤리딘
FR2792938A1 (fr) NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
JPS59206386A (ja) 三環式エーテル及びこれを含有する胃保護作用―及び胃酸分泌抑制剤
JP5092746B2 (ja) アシルグアニジン誘導体またはその塩
EP0546181A1 (fr) Derives d'indole et leurs utilisation comme antagoniste du serotonin
KR100240242B1 (ko) 광학활성 알킬렌디옥시벤젠 유도체 및 치료에의 용도
CA2097607A1 (fr) Utilisation de certains derives de glutarimide dans le traitement de la depression et de la manie
WO2004099214A1 (fr) Amino-pyranoquinoleines en tant qu'inhibiteurs de recaptage de la serotonine et agonistes de recepteurs 5-ht1a
WO2019082910A1 (fr) Antagoniste des récepteurs de la vasopressine
EP0355169A1 (fr) Utilisation de dérivés pipérazine dans la fabrication d'un médicament pour le traitement de l'anxiété
JP2899433B2 (ja) アルキレンジオキシベンゼン誘導体およびそれを有効成分とする抗不安薬
JP2799892B2 (ja) 新規な誘導体類
FR2537582A1 (fr) Nouveaux derives de l'ethylene-diamine et de la guanidine
WO2002018344A1 (fr) Nouveaux derives esteriques ou amidiques
US7816362B2 (en) Serotonergic agents
JP3165409B2 (ja) アルキレンジオキシベンゼン誘導体を有効成分とする抗不安薬
US5234948A (en) Optically active alkylenedioxybenzene derivatives and their use in therapy
SU1517759A3 (ru) Способ получени 4-амино-2-(2-бутанон-3-ил)-окси-5-хлор-N-[2-(диэтиламино)этил]бензамида или его солей
EP0236931B1 (fr) Dérivés aromatiques d'oméga-alkylimino-tétrahydro-6H-1,3-thiazin-6-one
EP0492021A1 (fr) Utilisation de certains dérivés de 1,2-benzo-isothiazole-3(2H)-1,1-dioxyde dans le traitement de dépression et manie
CA2203664A1 (fr) Derives d'oxazepine et de thiazepine tetracycliques substitues, presentant une affinite pour les recepteurs 5-ht2

Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 19950604