CA2088128C - Salts of glucopyranose derivatives and its intermediate - Google Patents
Salts of glucopyranose derivatives and its intermediate Download PDFInfo
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- CA2088128C CA2088128C CA002088128A CA2088128A CA2088128C CA 2088128 C CA2088128 C CA 2088128C CA 002088128 A CA002088128 A CA 002088128A CA 2088128 A CA2088128 A CA 2088128A CA 2088128 C CA2088128 C CA 2088128C
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- 150000003839 salts Chemical class 0.000 title claims abstract description 39
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical class OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 21
- 150000001875 compounds Chemical class 0.000 claims abstract description 74
- 238000002360 preparation method Methods 0.000 claims abstract description 30
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229910001415 sodium ion Inorganic materials 0.000 claims abstract description 8
- DRDCQJADRSJFFD-UHFFFAOYSA-N tris-hydroxymethyl-methyl-ammonium Chemical compound OC[N+](C)(CO)CO DRDCQJADRSJFFD-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000000203 mixture Substances 0.000 claims description 78
- 238000000034 method Methods 0.000 claims description 55
- 238000006243 chemical reaction Methods 0.000 claims description 26
- 239000011734 sodium Substances 0.000 claims description 22
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 19
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- 239000011575 calcium Substances 0.000 claims description 11
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- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 5
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
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JP4-42185 | 1992-01-31 | ||
JP4218592 | 1992-01-31 | ||
JP15591392 | 1992-05-22 | ||
JP4-155913 | 1992-05-22 |
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CA2088128A1 CA2088128A1 (en) | 1993-08-01 |
CA2088128C true CA2088128C (en) | 2002-10-29 |
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CA002088128A Expired - Fee Related CA2088128C (en) | 1992-01-31 | 1993-01-26 | Salts of glucopyranose derivatives and its intermediate |
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US (2) | US5294723A (en:Method) |
EP (1) | EP0553786B1 (en:Method) |
JP (2) | JP2657752B2 (en:Method) |
KR (1) | KR0168876B1 (en:Method) |
AT (1) | ATE216393T1 (en:Method) |
CA (1) | CA2088128C (en:Method) |
DE (1) | DE69331814T2 (en:Method) |
DK (1) | DK0553786T3 (en:Method) |
ES (1) | ES2174840T3 (en:Method) |
PT (1) | PT553786E (en:Method) |
TW (1) | TW301653B (en:Method) |
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JP3057226B2 (ja) * | 1997-10-09 | 2000-06-26 | 琉球大学長 | グルコピラノース誘導体を有効成分とするリーシュマニア症治療剤 |
WO1999056744A1 (fr) | 1998-05-06 | 1999-11-11 | Ono Pharmaceutical Co., Ltd. | Immunosuppresseur contenant un derive de glucopyranose comme principe actif |
JP2020152674A (ja) * | 2019-03-20 | 2020-09-24 | 株式会社リコー | 難水溶性化合物の可溶化物の製造方法 |
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DE2635985A1 (de) * | 1976-08-06 | 1978-02-09 | Schering Ag | Prostansaeurederivat und verfahren zu ihrer herstellung |
DE3683836D1 (de) * | 1985-12-06 | 1992-03-19 | Ono Pharmaceutical Co | Glucopyranose-derivate. |
US4925929A (en) * | 1985-12-06 | 1990-05-15 | Ono Pharmaceutical Co. Ltd. | Glucopyranose derivatives |
JPS63179885A (ja) * | 1985-12-06 | 1988-07-23 | Ono Pharmaceut Co Ltd | 新規なグリコピラノース誘導体 |
-
1993
- 1993-01-26 CA CA002088128A patent/CA2088128C/en not_active Expired - Fee Related
- 1993-01-27 DE DE69331814T patent/DE69331814T2/de not_active Expired - Fee Related
- 1993-01-27 JP JP5031313A patent/JP2657752B2/ja not_active Expired - Fee Related
- 1993-01-27 EP EP93101202A patent/EP0553786B1/en not_active Expired - Lifetime
- 1993-01-27 ES ES93101202T patent/ES2174840T3/es not_active Expired - Lifetime
- 1993-01-27 PT PT93101202T patent/PT553786E/pt unknown
- 1993-01-27 AT AT93101202T patent/ATE216393T1/de not_active IP Right Cessation
- 1993-01-27 DK DK93101202T patent/DK0553786T3/da active
- 1993-01-28 US US08/010,163 patent/US5294723A/en not_active Expired - Fee Related
- 1993-01-30 TW TW082100596A patent/TW301653B/zh active
- 1993-01-30 KR KR1019930001202A patent/KR0168876B1/ko not_active Expired - Fee Related
-
1995
- 1995-06-05 US US08/465,470 patent/US5733927A/en not_active Expired - Fee Related
-
1997
- 1997-02-14 JP JP9047034A patent/JP2906228B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW301653B (en:Method) | 1997-04-01 |
JP2657752B2 (ja) | 1997-09-24 |
KR930016434A (ko) | 1993-08-26 |
ATE216393T1 (de) | 2002-05-15 |
EP0553786B1 (en) | 2002-04-17 |
EP0553786A3 (en) | 1996-03-13 |
JPH0641175A (ja) | 1994-02-15 |
DK0553786T3 (da) | 2002-08-12 |
JPH09194495A (ja) | 1997-07-29 |
US5294723A (en) | 1994-03-15 |
US5733927A (en) | 1998-03-31 |
EP0553786A2 (en) | 1993-08-04 |
DE69331814T2 (de) | 2002-11-28 |
CA2088128A1 (en) | 1993-08-01 |
ES2174840T3 (es) | 2002-11-16 |
KR0168876B1 (ko) | 1999-01-15 |
JP2906228B2 (ja) | 1999-06-14 |
PT553786E (pt) | 2002-08-30 |
DE69331814D1 (de) | 2002-05-23 |
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