CA2035032A1 - Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy - Google Patents

Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Info

Publication number
CA2035032A1
CA2035032A1 CA002035032A CA2035032A CA2035032A1 CA 2035032 A1 CA2035032 A1 CA 2035032A1 CA 002035032 A CA002035032 A CA 002035032A CA 2035032 A CA2035032 A CA 2035032A CA 2035032 A1 CA2035032 A1 CA 2035032A1
Authority
CA
Canada
Prior art keywords
hydrogen
coor7
imidazolyl
alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002035032A
Other languages
English (en)
French (fr)
Inventor
Patricia Salvati
Corrado Ferti
Paolo Cozzi
Paola Alessandrini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2035032A1 publication Critical patent/CA2035032A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002035032A 1989-06-23 1990-06-25 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy Abandoned CA2035032A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8914525.4 1989-06-23
GB898914525A GB8914525D0 (en) 1989-06-23 1989-06-23 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Publications (1)

Publication Number Publication Date
CA2035032A1 true CA2035032A1 (en) 1990-12-24

Family

ID=10658992

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002035032A Abandoned CA2035032A1 (en) 1989-06-23 1990-06-25 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Country Status (13)

Country Link
EP (1) EP0433427A1 (ja)
JP (1) JPH04500375A (ja)
KR (1) KR920700669A (ja)
AU (1) AU636898B2 (ja)
CA (1) CA2035032A1 (ja)
GB (1) GB8914525D0 (ja)
HU (1) HUT55989A (ja)
IE (1) IE902266A1 (ja)
IL (1) IL94765A0 (ja)
MY (1) MY105822A (ja)
PT (1) PT94464A (ja)
WO (1) WO1991000102A1 (ja)
ZA (1) ZA904882B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2141705B (en) * 1983-06-20 1986-09-24 Erba Farmitalia Imidazoles
EP0300675A3 (en) * 1987-07-21 1990-04-11 Merck Frosst Canada Inc. Method for the improvement of cyclosporine therapy

Also Published As

Publication number Publication date
PT94464A (pt) 1991-02-08
JPH04500375A (ja) 1992-01-23
IE902266A1 (en) 1991-01-16
WO1991000102A1 (en) 1991-01-10
KR920700669A (ko) 1992-08-10
AU5958490A (en) 1991-01-17
IL94765A0 (en) 1991-04-15
ZA904882B (en) 1992-02-26
MY105822A (en) 1995-01-30
HUT55989A (en) 1991-07-29
GB8914525D0 (en) 1989-08-09
EP0433427A1 (en) 1991-06-26
HU905625D0 (en) 1991-06-28
AU636898B2 (en) 1993-05-13

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Legal Events

Date Code Title Description
FZDE Discontinued