AU636898B2 - Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy - Google Patents

Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Info

Publication number
AU636898B2
AU636898B2 AU59584/90A AU5958490A AU636898B2 AU 636898 B2 AU636898 B2 AU 636898B2 AU 59584/90 A AU59584/90 A AU 59584/90A AU 5958490 A AU5958490 A AU 5958490A AU 636898 B2 AU636898 B2 AU 636898B2
Authority
AU
Australia
Prior art keywords
hydrogen
imidazolyl
formula
compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU59584/90A
Other languages
English (en)
Other versions
AU5958490A (en
Inventor
Paolo Alessandrini
Paolo Cozzi
Corrado Ferti
Patricia Salvati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU5958490A publication Critical patent/AU5958490A/en
Application granted granted Critical
Publication of AU636898B2 publication Critical patent/AU636898B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU59584/90A 1989-06-23 1990-06-25 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy Ceased AU636898B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8914525 1989-06-23
GB898914525A GB8914525D0 (en) 1989-06-23 1989-06-23 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Publications (2)

Publication Number Publication Date
AU5958490A AU5958490A (en) 1991-01-17
AU636898B2 true AU636898B2 (en) 1993-05-13

Family

ID=10658992

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59584/90A Ceased AU636898B2 (en) 1989-06-23 1990-06-25 Combined use of n-imidazolyl derivatives of bicyclic compounds and cyclosporine in therapy

Country Status (13)

Country Link
EP (1) EP0433427A1 (ja)
JP (1) JPH04500375A (ja)
KR (1) KR920700669A (ja)
AU (1) AU636898B2 (ja)
CA (1) CA2035032A1 (ja)
GB (1) GB8914525D0 (ja)
HU (1) HUT55989A (ja)
IE (1) IE902266A1 (ja)
IL (1) IL94765A0 (ja)
MY (1) MY105822A (ja)
PT (1) PT94464A (ja)
WO (1) WO1991000102A1 (ja)
ZA (1) ZA904882B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2141705B (en) * 1983-06-20 1986-09-24 Erba Farmitalia Imidazoles
EP0300675A3 (en) * 1987-07-21 1990-04-11 Merck Frosst Canada Inc. Method for the improvement of cyclosporine therapy

Also Published As

Publication number Publication date
PT94464A (pt) 1991-02-08
IL94765A0 (en) 1991-04-15
ZA904882B (en) 1992-02-26
IE902266A1 (en) 1991-01-16
KR920700669A (ko) 1992-08-10
CA2035032A1 (en) 1990-12-24
WO1991000102A1 (en) 1991-01-10
MY105822A (en) 1995-01-30
JPH04500375A (ja) 1992-01-23
EP0433427A1 (en) 1991-06-26
HU905625D0 (en) 1991-06-28
HUT55989A (en) 1991-07-29
AU5958490A (en) 1991-01-17
GB8914525D0 (en) 1989-08-09

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