CA1312605C - 3-aryl-5-alkylthio-4h-1,2,4-triazoles - Google Patents
3-aryl-5-alkylthio-4h-1,2,4-triazolesInfo
- Publication number
- CA1312605C CA1312605C CA000557078A CA557078A CA1312605C CA 1312605 C CA1312605 C CA 1312605C CA 000557078 A CA000557078 A CA 000557078A CA 557078 A CA557078 A CA 557078A CA 1312605 C CA1312605 C CA 1312605C
- Authority
- CA
- Canada
- Prior art keywords
- methyl
- zero
- phenyl
- triazole
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US706387A | 1987-01-27 | 1987-01-27 | |
| US007,063 | 1987-01-27 | ||
| US126,191 | 1987-12-04 | ||
| US07/126,191 US4900743A (en) | 1987-01-27 | 1987-12-04 | 3-aryl-5-alkylthio-4H-1,2,4-triazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1312605C true CA1312605C (en) | 1993-01-12 |
Family
ID=26676435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000557078A Expired - Fee Related CA1312605C (en) | 1987-01-27 | 1988-01-21 | 3-aryl-5-alkylthio-4h-1,2,4-triazoles |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4900743A (pt) |
| EP (1) | EP0276793B1 (pt) |
| JP (1) | JP2537651B2 (pt) |
| KR (1) | KR960007166B1 (pt) |
| CN (1) | CN1023480C (pt) |
| AR (1) | AR244682A1 (pt) |
| AU (1) | AU601013B2 (pt) |
| CA (1) | CA1312605C (pt) |
| DE (1) | DE3881712T2 (pt) |
| DK (1) | DK171599B1 (pt) |
| ES (1) | ES2058144T3 (pt) |
| FI (1) | FI91526C (pt) |
| HU (1) | HU205747B (pt) |
| IE (1) | IE61188B1 (pt) |
| IL (1) | IL85185A (pt) |
| NO (1) | NO166642C (pt) |
| NZ (1) | NZ223260A (pt) |
| PH (1) | PH24513A (pt) |
| PT (1) | PT86623B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2948189A (en) * | 1987-12-31 | 1989-08-01 | Smithkline Beckman Corporation | 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols |
| AU644500B2 (en) * | 1990-12-20 | 1993-12-09 | Merrell Dow Pharmaceuticals Inc. | 3-aryl-5-alkylthio-4h-1,2,4-triazoles for treatment of hyperreflexia due to spinal trauma |
| DE4339412A1 (de) * | 1993-11-18 | 1995-05-24 | Bayer Ag | Verfahren und neue Zwischenprodukte zur Herstellung von Triazolinonen |
| AR032653A1 (es) | 2001-02-09 | 2003-11-19 | Telik Inc | Inhibidores heterociclicos del trasportador de glicina 2 composiciones farmaceuticas, uso y metodos. |
| CN1736381B (zh) * | 2005-08-11 | 2010-09-08 | 沈阳药科大学 | 吗啉甲基萘满酮用于制备平滑肌解痉剂的用途 |
| AU2009325178A1 (en) * | 2008-12-12 | 2010-06-17 | Astrazeneca Ab | A new process for preparing 4- [4-methyl-5- (Cl- 10alkylthio/C5-10aryl-Cl-6alkylthio) -4H-1, 2, 4-triazol-3- YL] pyridines. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU193891B (en) * | 1984-02-07 | 1987-12-28 | Gyogyszerkutato Intezet | Process for production of new derivatives of 1,2,4-triasole |
-
1987
- 1987-12-04 US US07/126,191 patent/US4900743A/en not_active Expired - Lifetime
-
1988
- 1988-01-21 NZ NZ223260A patent/NZ223260A/en unknown
- 1988-01-21 CA CA000557078A patent/CA1312605C/en not_active Expired - Fee Related
- 1988-01-22 FI FI880282A patent/FI91526C/fi not_active IP Right Cessation
- 1988-01-22 AU AU10728/88A patent/AU601013B2/en not_active Ceased
- 1988-01-25 IL IL8518588A patent/IL85185A/en not_active IP Right Cessation
- 1988-01-25 AR AR88309910A patent/AR244682A1/es active
- 1988-01-25 ES ES88101023T patent/ES2058144T3/es not_active Expired - Lifetime
- 1988-01-25 EP EP88101023A patent/EP0276793B1/en not_active Expired - Lifetime
- 1988-01-25 HU HU88280D patent/HU205747B/hu not_active IP Right Cessation
- 1988-01-25 DE DE88101023T patent/DE3881712T2/de not_active Expired - Fee Related
- 1988-01-26 NO NO880337A patent/NO166642C/no unknown
- 1988-01-26 CN CN88100346A patent/CN1023480C/zh not_active Expired - Fee Related
- 1988-01-26 PT PT86623A patent/PT86623B/pt not_active IP Right Cessation
- 1988-01-26 DK DK035488A patent/DK171599B1/da not_active IP Right Cessation
- 1988-01-26 KR KR1019880000562A patent/KR960007166B1/ko not_active IP Right Cessation
- 1988-01-26 IE IE19188A patent/IE61188B1/en not_active IP Right Cessation
- 1988-01-27 PH PH36413A patent/PH24513A/en unknown
- 1988-01-27 JP JP63014787A patent/JP2537651B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI91526C (fi) | 1994-07-11 |
| FI91526B (fi) | 1994-03-31 |
| NO880337L (no) | 1988-07-28 |
| DE3881712T2 (de) | 1993-12-23 |
| NZ223260A (en) | 1991-07-26 |
| IE61188B1 (en) | 1994-10-19 |
| IL85185A0 (en) | 1988-07-31 |
| JPS63201176A (ja) | 1988-08-19 |
| DK171599B1 (da) | 1997-02-17 |
| PH24513A (en) | 1990-07-18 |
| ES2058144T3 (es) | 1994-11-01 |
| PT86623B (pt) | 1993-01-29 |
| AU601013B2 (en) | 1990-08-30 |
| EP0276793A2 (en) | 1988-08-03 |
| NO166642C (no) | 1991-08-21 |
| AU1072888A (en) | 1988-07-28 |
| HU205747B (en) | 1992-06-29 |
| DK35488D0 (da) | 1988-01-26 |
| FI880282A0 (fi) | 1988-01-22 |
| DK35488A (da) | 1988-07-28 |
| KR880008999A (ko) | 1988-09-13 |
| PT86623A (pt) | 1988-02-01 |
| NO880337D0 (no) | 1988-01-26 |
| KR960007166B1 (ko) | 1996-05-29 |
| CN1023480C (zh) | 1994-01-12 |
| FI880282A (fi) | 1988-07-28 |
| CN88100346A (zh) | 1988-11-02 |
| US4900743A (en) | 1990-02-13 |
| EP0276793A3 (en) | 1988-09-21 |
| DE3881712D1 (de) | 1993-07-22 |
| IL85185A (en) | 1996-03-31 |
| HUT47257A (en) | 1989-02-28 |
| NO166642B (no) | 1991-05-13 |
| AR244682A1 (es) | 1993-11-30 |
| EP0276793B1 (en) | 1993-06-16 |
| JP2537651B2 (ja) | 1996-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed | ||
| MKLA | Lapsed |
Effective date: 20050112 |