CA1256883C - - Google Patents

Info

Publication number
CA1256883C
CA1256883C CA 474316 CA474316A CA1256883C CA 1256883 C CA1256883 C CA 1256883C CA 474316 CA474316 CA 474316 CA 474316 A CA474316 A CA 474316A CA 1256883 C CA1256883 C CA 1256883C
Authority
CA
Canada
Prior art keywords
sup
alkyl
hydrogen
benzyl
deprotected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA 474316
Other languages
English (en)
Other versions
CA1241333A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA000558327A priority Critical patent/CA1256883A/en
Publication of CA1241333A publication Critical patent/CA1241333A/en
Application granted granted Critical
Publication of CA1256883C publication Critical patent/CA1256883C/xx
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA000474316A 1984-02-27 1985-02-14 PREPARATION OF PYRROLIDONE DERIVATIVES Expired CA1241333A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000558327A CA1256883A (en) 1984-02-27 1988-02-05 Intermediates for preparing pyrrolidinone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419802A IT1206699B (it) 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone.

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA000558327A Division CA1256883A (en) 1984-02-27 1988-02-05 Intermediates for preparing pyrrolidinone derivatives

Publications (2)

Publication Number Publication Date
CA1241333A CA1241333A (en) 1988-08-30
CA1256883C true CA1256883C (ko) 1989-07-04

Family

ID=11161351

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000474316A Expired CA1241333A (en) 1984-02-27 1985-02-14 PREPARATION OF PYRROLIDONE DERIVATIVES

Country Status (20)

Country Link
US (1) US4797496A (ko)
EP (1) EP0154490B1 (ko)
JP (1) JPH0791266B2 (ko)
KR (1) KR920002295B1 (ko)
AT (1) ATE36319T1 (ko)
AU (2) AU584605B2 (ko)
CA (1) CA1241333A (ko)
DE (1) DE3564264D1 (ko)
DK (1) DK86185A (ko)
ES (2) ES8700656A1 (ko)
FI (1) FI81339C (ko)
GR (1) GR850485B (ko)
HU (2) HU193399B (ko)
IL (1) IL74448A (ko)
IT (1) IT1206699B (ko)
NO (1) NO166712C (ko)
NZ (1) NZ211226A (ko)
PH (1) PH22518A (ko)
PT (1) PT80021B (ko)
ZA (1) ZA851401B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686296A (en) * 1985-07-26 1987-08-11 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
DE3602254A1 (de) * 1986-01-25 1987-07-30 Basf Ag Verfahren zur herstellung von oxiranylcarbonsaeureestern
CH680293A5 (ko) * 1990-06-26 1992-07-31 Lonza Ag
KR100424393B1 (ko) * 2001-11-26 2004-03-24 한국화학연구원 옥시라세탐의 제조방법
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
CN102249977B (zh) * 2011-08-11 2013-06-12 重庆润泽医药有限公司 4-羟基-2-氧代-1-吡咯烷乙酰胺外消旋体晶型ⅰ及其制备方法
CN102432516B (zh) * 2011-12-14 2013-10-09 山东阿如拉药物研究开发有限公司 奥拉西坦的精制方法
CN110615744B (zh) * 2018-06-20 2023-01-06 上海朴颐化学科技有限公司 一种布瓦西坦中间体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI51098C (fi) * 1975-03-27 1976-10-11 Medipolar Oy Menetelmä terapeuttisesti arvokkaan 2-okso-1-pyrrolidinyyliasetamidin valmistamiseksi.
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
IT1075280B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
IT1075564B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
JPS5812272B2 (ja) * 1981-04-28 1983-03-07 電気化学工業株式会社 4−ヒドロキシ−2−ピロリドンの製造法
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti

Also Published As

Publication number Publication date
JPH0791266B2 (ja) 1995-10-04
IL74448A0 (en) 1985-05-31
AU584605B2 (en) 1989-06-01
EP0154490A2 (en) 1985-09-11
EP0154490A3 (en) 1986-02-12
GR850485B (ko) 1985-06-26
DK86185A (da) 1985-08-28
HU193399B (en) 1987-10-28
IT1206699B (it) 1989-04-27
DE3564264D1 (en) 1988-09-15
ZA851401B (en) 1985-11-27
IL74448A (en) 1989-01-31
PT80021B (pt) 1987-06-17
ES8800135A1 (es) 1987-10-16
NO850778L (no) 1985-08-28
KR920002295B1 (ko) 1992-03-21
ES8700656A1 (es) 1986-10-16
ES552957A0 (es) 1987-10-16
AU612000B2 (en) 1991-06-27
FI81339B (fi) 1990-06-29
NO166712B (no) 1991-05-21
ATE36319T1 (de) 1988-08-15
HU195957B (en) 1988-08-29
KR850006171A (ko) 1985-10-02
EP0154490B1 (en) 1988-08-10
HUT38614A (en) 1986-06-30
DK86185D0 (da) 1985-02-26
AU3918085A (en) 1985-09-05
HUT41391A (en) 1987-04-28
NO166712C (no) 1991-08-28
FI850505A0 (fi) 1985-02-07
IT8419802A0 (it) 1984-02-27
US4797496A (en) 1989-01-10
PH22518A (en) 1988-09-12
CA1241333A (en) 1988-08-30
ES540601A0 (es) 1986-10-16
NZ211226A (en) 1990-06-26
AU3024789A (en) 1989-06-22
FI850505L (fi) 1985-08-28
FI81339C (fi) 1990-10-10
JPS60208957A (ja) 1985-10-21

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Legal Events

Date Code Title Description
MKEX Expiry