ES8800135A1 - Un procedimiento para preparar derivados de esteres alquilicos del acido b-hidroxibutanoico - Google Patents

Un procedimiento para preparar derivados de esteres alquilicos del acido b-hidroxibutanoico

Info

Publication number
ES8800135A1
ES8800135A1 ES552957A ES552957A ES8800135A1 ES 8800135 A1 ES8800135 A1 ES 8800135A1 ES 552957 A ES552957 A ES 552957A ES 552957 A ES552957 A ES 552957A ES 8800135 A1 ES8800135 A1 ES 8800135A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
image
preparation
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552957A
Other languages
English (en)
Other versions
ES552957A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of ES8800135A1 publication Critical patent/ES8800135A1/es
Publication of ES552957A0 publication Critical patent/ES552957A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ESTERES ALQUILICOS DEL ACIDO BETA-HIDROXIBUTANOICO. CONSISTE EN HACER REACCIONAR A UN 3,4-EPOXIBUTANOATO DE ALQUILO DE FORMULA (II) CON UN DERIVADO DE GUICINAMIDA DE FORMULA (III), EN UN HIDROCARBURO ALIFATICO Y ENTRE 20 Y 120GC, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R ELEVADO A 1 Y R ELEVADO A 3, HIDROGENO; R ELEVADO A 2, BENCILO; Y X, ALQUILO DE C 1 A 10. SE UTILIZAN COMO AGENTES PSICOTROPICOS VALIOSOS EN MAMIFEROS, PARA RESTABLECER LA FUNCION COONITA DAÑADA POR PATOLOGIAS. *FORMULA*
ES552957A 1984-02-27 1986-03-13 Un procedimiento para preparar derivados de esteres alquilicos del acido b-hidroxibutanoico Expired ES8800135A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419802A IT1206699B (it) 1984-02-27 1984-02-27 Procedimento per preparare derivati di pirrolidone.

Publications (2)

Publication Number Publication Date
ES8800135A1 true ES8800135A1 (es) 1987-10-16
ES552957A0 ES552957A0 (es) 1987-10-16

Family

ID=11161351

Family Applications (2)

Application Number Title Priority Date Filing Date
ES540601A Expired ES8700656A1 (es) 1984-02-27 1985-02-21 Un procedimiento para preparar un derivado de pirrolidinona.
ES552957A Expired ES8800135A1 (es) 1984-02-27 1986-03-13 Un procedimiento para preparar derivados de esteres alquilicos del acido b-hidroxibutanoico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES540601A Expired ES8700656A1 (es) 1984-02-27 1985-02-21 Un procedimiento para preparar un derivado de pirrolidinona.

Country Status (20)

Country Link
US (1) US4797496A (es)
EP (1) EP0154490B1 (es)
JP (1) JPH0791266B2 (es)
KR (1) KR920002295B1 (es)
AT (1) ATE36319T1 (es)
AU (2) AU584605B2 (es)
CA (1) CA1241333A (es)
DE (1) DE3564264D1 (es)
DK (1) DK86185A (es)
ES (2) ES8700656A1 (es)
FI (1) FI81339C (es)
GR (1) GR850485B (es)
HU (2) HU193399B (es)
IL (1) IL74448A (es)
IT (1) IT1206699B (es)
NO (1) NO166712C (es)
NZ (1) NZ211226A (es)
PH (1) PH22518A (es)
PT (1) PT80021B (es)
ZA (1) ZA851401B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686296A (en) * 1985-07-26 1987-08-11 Denki Kagaku Kogyo Kabushiki Kaisha Process for producing oxiracetam
CH668423A5 (de) * 1986-06-19 1988-12-30 Lonza Ag Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen.
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
DE3602254A1 (de) * 1986-01-25 1987-07-30 Basf Ag Verfahren zur herstellung von oxiranylcarbonsaeureestern
CH680293A5 (es) * 1990-06-26 1992-07-31 Lonza Ag
KR100424393B1 (ko) * 2001-11-26 2004-03-24 한국화학연구원 옥시라세탐의 제조방법
CN101704778B (zh) * 2009-09-30 2012-10-17 厦门市华兴化工有限公司 一种制备4-羟基吡咯烷酮-2-乙酰胺的方法
CN102249977B (zh) * 2011-08-11 2013-06-12 重庆润泽医药有限公司 4-羟基-2-氧代-1-吡咯烷乙酰胺外消旋体晶型ⅰ及其制备方法
CN102432516B (zh) * 2011-12-14 2013-10-09 山东阿如拉药物研究开发有限公司 奥拉西坦的精制方法
CN110615744B (zh) * 2018-06-20 2023-01-06 上海朴颐化学科技有限公司 一种布瓦西坦中间体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI51098C (fi) * 1975-03-27 1976-10-11 Medipolar Oy Menetelmä terapeuttisesti arvokkaan 2-okso-1-pyrrolidinyyliasetamidin valmistamiseksi.
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
IT1075564B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
IT1075280B (it) * 1977-02-11 1985-04-22 Isf Spa Procedimento per la preparazione di derivati pirrolidinici
JPS5812272B2 (ja) * 1981-04-28 1983-03-07 電気化学工業株式会社 ４−ヒドロキシ−２−ピロリドンの製造法
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
IT1173768B (it) * 1984-04-02 1987-06-24 Isf Spa Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti

Also Published As

Publication number Publication date
IL74448A (en) 1989-01-31
AU584605B2 (en) 1989-06-01
ES8700656A1 (es) 1986-10-16
FI850505L (fi) 1985-08-28
HU195957B (en) 1988-08-29
HUT38614A (en) 1986-06-30
NZ211226A (en) 1990-06-26
IT8419802A0 (it) 1984-02-27
AU612000B2 (en) 1991-06-27
CA1256883C (es) 1989-07-04
ZA851401B (en) 1985-11-27
FI850505A0 (fi) 1985-02-07
DK86185D0 (da) 1985-02-26
DE3564264D1 (en) 1988-09-15
PT80021B (pt) 1987-06-17
NO166712B (no) 1991-05-21
NO166712C (no) 1991-08-28
EP0154490A3 (en) 1986-02-12
ATE36319T1 (de) 1988-08-15
NO850778L (no) 1985-08-28
EP0154490A2 (en) 1985-09-11
AU3918085A (en) 1985-09-05
IL74448A0 (en) 1985-05-31
ES540601A0 (es) 1986-10-16
EP0154490B1 (en) 1988-08-10
JPS60208957A (ja) 1985-10-21
IT1206699B (it) 1989-04-27
DK86185A (da) 1985-08-28
PH22518A (en) 1988-09-12
FI81339C (fi) 1990-10-10
HUT41391A (en) 1987-04-28
ES552957A0 (es) 1987-10-16
GR850485B (es) 1985-06-26
FI81339B (fi) 1990-06-29
JPH0791266B2 (ja) 1995-10-04
KR920002295B1 (ko) 1992-03-21
CA1241333A (en) 1988-08-30
AU3024789A (en) 1989-06-22
HU193399B (en) 1987-10-28
KR850006171A (ko) 1985-10-02
US4797496A (en) 1989-01-10

Similar Documents

Publication Publication Date Title
IE820753L (en) Acyl dipeptides
ES8401443A1 (es) "un procedimiento para preparar derivados de tetralina".
ES8700656A1 (es) Un procedimiento para preparar un derivado de pirrolidinona.
ES8505518A1 (es) Procedimiento para preparar derivados de aminoacidos
ES8700655A1 (es) Un procedimiento para preparar derivados de pirrolidona
YU196483A (en) Process for obtaining (1-arylcyclobutyl)-alkylamine compounds
HUT47941A (en) Process for producing cefem compounds and new cefalosporin derivatives
IE873182L (en) Triazaspirodecanylmethylindolone derivatives
DE3260654D1 (en) N-(2-(2-amino-2-phenylethyl)phenyl)-2,2-dimethyl-propanamid and derivatives and a process for preparing the same
ES8702889A1 (es) Un procedimiento para la preparacion de acidos pirrilidinpropanoicos.
PT85070A (en) Process for the preparation of derivatives of fused tricyclic lactams useful in inhibiting the angiotensin coverting enzyme

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303