CA1220468A - Process for the production of 17-esters of clobetasol - Google Patents

Process for the production of 17-esters of clobetasol

Info

Publication number
CA1220468A
CA1220468A CA000445603A CA445603A CA1220468A CA 1220468 A CA1220468 A CA 1220468A CA 000445603 A CA000445603 A CA 000445603A CA 445603 A CA445603 A CA 445603A CA 1220468 A CA1220468 A CA 1220468A
Authority
CA
Canada
Prior art keywords
beta
epoxy
dione
diene
methylpregna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000445603A
Other languages
English (en)
French (fr)
Inventor
Peter Macdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SICOR Societa Italiana Corticosteroidi SRL
Original Assignee
SICOR Societa Italiana Corticosteroidi SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SICOR Societa Italiana Corticosteroidi SRL filed Critical SICOR Societa Italiana Corticosteroidi SRL
Application granted granted Critical
Publication of CA1220468A publication Critical patent/CA1220468A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000445603A 1983-03-29 1984-01-19 Process for the production of 17-esters of clobetasol Expired CA1220468A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20334A/83 1983-03-29
IT20334/83A IT1194178B (it) 1983-03-29 1983-03-29 Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti

Publications (1)

Publication Number Publication Date
CA1220468A true CA1220468A (en) 1987-04-14

Family

ID=11165811

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000445603A Expired CA1220468A (en) 1983-03-29 1984-01-19 Process for the production of 17-esters of clobetasol

Country Status (10)

Country Link
JP (2) JPS59205399A (enrdf_load_stackoverflow)
CA (1) CA1220468A (enrdf_load_stackoverflow)
CH (1) CH661930A5 (enrdf_load_stackoverflow)
DK (1) DK42884A (enrdf_load_stackoverflow)
FI (1) FI840344A7 (enrdf_load_stackoverflow)
IT (1) IT1194178B (enrdf_load_stackoverflow)
NL (1) NL8400910A (enrdf_load_stackoverflow)
NO (1) NO840065L (enrdf_load_stackoverflow)
SE (1) SE8400145L (enrdf_load_stackoverflow)
YU (1) YU54684A (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727458A (zh) * 2018-05-10 2018-11-02 浙江仙居仙乐药业有限公司 一种17-丙酸酯的合成方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111944002A (zh) * 2020-07-29 2020-11-17 河南利华制药有限公司 一种倍氯米松二丙酸酯中间体及制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1253831A (en) * 1968-01-19 1971-11-17 Glaxo Lab Ltd 9alpha,21-DIHALOPREGNANE COMPOUNDS
JPS51125372A (en) * 1975-03-31 1976-11-01 Taisho Pharmaceut Co Ltd Aprocess for preparing pregnane steroid-17-ester-21-halides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727458A (zh) * 2018-05-10 2018-11-02 浙江仙居仙乐药业有限公司 一种17-丙酸酯的合成方法

Also Published As

Publication number Publication date
IT8320334A0 (it) 1983-03-29
DK42884A (da) 1984-09-30
NL8400910A (nl) 1984-10-16
DK42884D0 (da) 1984-01-31
FI840344L (fi) 1984-09-30
SE8400145D0 (sv) 1984-01-12
IT1194178B (it) 1988-09-14
CH661930A5 (en) 1987-08-31
FI840344A7 (fi) 1984-09-30
SE8400145L (sv) 1984-09-30
JPS59205397A (ja) 1984-11-20
NO840065L (no) 1984-10-01
JPS6228160B2 (enrdf_load_stackoverflow) 1987-06-18
JPS59205399A (ja) 1984-11-20
FI840344A0 (fi) 1984-01-27
YU54684A (en) 1986-10-31

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Legal Events

Date Code Title Description
MKEX Expiry