CA1220468A - Procede de production de 17-esters de clobetasol - Google Patents
Procede de production de 17-esters de clobetasolInfo
- Publication number
- CA1220468A CA1220468A CA000445603A CA445603A CA1220468A CA 1220468 A CA1220468 A CA 1220468A CA 000445603 A CA000445603 A CA 000445603A CA 445603 A CA445603 A CA 445603A CA 1220468 A CA1220468 A CA 1220468A
- Authority
- CA
- Canada
- Prior art keywords
- beta
- epoxy
- dione
- diene
- methylpregna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20334A/83 | 1983-03-29 | ||
IT20334/83A IT1194178B (it) | 1983-03-29 | 1983-03-29 | Processo per la preparazione di 17-esteri di clobetasolo e composti ottenuti |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1220468A true CA1220468A (fr) | 1987-04-14 |
Family
ID=11165811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000445603A Expired CA1220468A (fr) | 1983-03-29 | 1984-01-19 | Procede de production de 17-esters de clobetasol |
Country Status (10)
Country | Link |
---|---|
JP (2) | JPS59205397A (fr) |
CA (1) | CA1220468A (fr) |
CH (1) | CH661930A5 (fr) |
DK (1) | DK42884A (fr) |
FI (1) | FI840344A (fr) |
IT (1) | IT1194178B (fr) |
NL (1) | NL8400910A (fr) |
NO (1) | NO840065L (fr) |
SE (1) | SE8400145L (fr) |
YU (1) | YU54684A (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108727458A (zh) * | 2018-05-10 | 2018-11-02 | 浙江仙居仙乐药业有限公司 | 一种17-丙酸酯的合成方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111944002A (zh) * | 2020-07-29 | 2020-11-17 | 河南利华制药有限公司 | 一种倍氯米松二丙酸酯中间体及制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1253831A (en) * | 1968-01-19 | 1971-11-17 | Glaxo Lab Ltd | 9alpha,21-DIHALOPREGNANE COMPOUNDS |
JPS51125372A (en) * | 1975-03-31 | 1976-11-01 | Taisho Pharmaceut Co Ltd | Aprocess for preparing pregnane steroid-17-ester-21-halides |
-
1983
- 1983-03-29 IT IT20334/83A patent/IT1194178B/it active
-
1984
- 1984-01-09 NO NO840065A patent/NO840065L/no unknown
- 1984-01-10 CH CH113/84A patent/CH661930A5/it not_active IP Right Cessation
- 1984-01-12 SE SE8400145A patent/SE8400145L/ not_active Application Discontinuation
- 1984-01-19 CA CA000445603A patent/CA1220468A/fr not_active Expired
- 1984-01-27 FI FI840344A patent/FI840344A/fi not_active Application Discontinuation
- 1984-01-31 JP JP59015956A patent/JPS59205397A/ja active Pending
- 1984-01-31 DK DK42884A patent/DK42884A/da not_active Application Discontinuation
- 1984-01-31 JP JP59015957A patent/JPS59205399A/ja active Granted
- 1984-03-22 NL NL8400910A patent/NL8400910A/nl not_active Application Discontinuation
- 1984-03-28 YU YU00546/84A patent/YU54684A/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108727458A (zh) * | 2018-05-10 | 2018-11-02 | 浙江仙居仙乐药业有限公司 | 一种17-丙酸酯的合成方法 |
Also Published As
Publication number | Publication date |
---|---|
DK42884A (da) | 1984-09-30 |
JPS6228160B2 (fr) | 1987-06-18 |
FI840344A0 (fi) | 1984-01-27 |
IT8320334A0 (it) | 1983-03-29 |
FI840344A (fi) | 1984-09-30 |
YU54684A (en) | 1986-10-31 |
NO840065L (no) | 1984-10-01 |
JPS59205397A (ja) | 1984-11-20 |
JPS59205399A (ja) | 1984-11-20 |
CH661930A5 (en) | 1987-08-31 |
SE8400145D0 (sv) | 1984-01-12 |
NL8400910A (nl) | 1984-10-16 |
DK42884D0 (da) | 1984-01-31 |
SE8400145L (sv) | 1984-09-30 |
IT1194178B (it) | 1988-09-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR890000761B1 (ko) | 스테로이드의 방향성 헤테로사이클릭 에스테르 및 이의 제조방법 | |
US4041055A (en) | Process for the preparation of 17α-hydroxyprogesterones and corticoids from androstenes | |
US4036831A (en) | Trimethyl siloxane steroid intermediates | |
CA2191324C (fr) | Procede pour preparer des .delta.9,11 et 21-chloro corticosteroides | |
EP1395603B1 (fr) | Preparation du flumethasone et de son analogue 17-carboxyle androstene | |
US4255331A (en) | 3-Acetoxy-9β-11β-epoxy-dienes and the preparation of the corresponding 6α-halogen-4-ene-3-ones | |
CA1220468A (fr) | Procede de production de 17-esters de clobetasol | |
CA1155108A (fr) | 17.alpha.-ACYLOXY-5.beta. ET 5.alpha.CORTICOIDES | |
CA1065848A (fr) | ESTERS ET ETHERS A BASE DE 16-METHYL-9.alpha.-HALOSTEROIDES ET LEUR PREPARATION | |
JPS591720B2 (ja) | 6−ハロ−プレグナン化合物の製造法 | |
JP2004534795A5 (fr) | ||
AU2002310616A1 (en) | Preparation of flumethasone and its 17-carboxyl androsten analogue | |
US4990612A (en) | 16α-methylation process | |
EP0097328A2 (fr) | Procédé de préparation de stéroides | |
JP2005530679A (ja) | 6α−フルオロコルチコステロイドの調製方法 | |
US4704455A (en) | 16α-methylatedΔ17(20)-corticoids | |
KR840001809B1 (ko) | 신규 선택적 용매화 분해방법 | |
KR960011781B1 (ko) | 16α-메틸화 공정 | |
EP0170500B1 (fr) | Esters de 9-alpha-fluoro ou chloro corticostéroides et procédé pour les préparer | |
DE2905674A1 (de) | Steroidverbindungen und verfahren zu ihrer herstellung | |
JP2000128897A (ja) | ブデソニドの22rエピマ―を調製する立体選択的な方法 | |
JPS5855156B2 (ja) | プレグナンケイノ 6 ベ−タ − フルオロ −3− ケト デルタ 1 4− ステロイドノ セイホウ | |
JPS5834480B2 (ja) | 16ベ−タ−メチル−17アルファ−アシロキシ−1.4−ジエン−21−ハロステロイド化合物の製法 | |
EP1275656A1 (fr) | Procédé de préparation de 16,17-acétales de 9alpha-fluoro-11beta-hydroxyprégnane |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |