CA1200239A - Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid - Google Patents

Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid

Info

Publication number
CA1200239A
CA1200239A CA000395121A CA395121A CA1200239A CA 1200239 A CA1200239 A CA 1200239A CA 000395121 A CA000395121 A CA 000395121A CA 395121 A CA395121 A CA 395121A CA 1200239 A CA1200239 A CA 1200239A
Authority
CA
Canada
Prior art keywords
weight
ampicillin
dioxo
alkyl
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000395121A
Other languages
English (en)
French (fr)
Inventor
Donald C. Boop
Karel F. Bernady
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of CA1200239A publication Critical patent/CA1200239A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
CA000395121A 1981-03-30 1982-01-28 Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid Expired CA1200239A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24875481A 1981-03-30 1981-03-30
US248,754 1981-03-30

Publications (1)

Publication Number Publication Date
CA1200239A true CA1200239A (en) 1986-02-04

Family

ID=22940531

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000395121A Expired CA1200239A (en) 1981-03-30 1982-01-28 Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid

Country Status (23)

Country Link
JP (1) JPS57165391A (xx)
AT (1) AT381706B (xx)
AU (1) AU544896B2 (xx)
BE (1) BE892586A (xx)
CA (1) CA1200239A (xx)
CH (1) CH654309A5 (xx)
DE (1) DE3208506A1 (xx)
DK (1) DK161079C (xx)
ES (1) ES8306376A1 (xx)
FR (1) FR2502623A1 (xx)
GB (1) GB2095661B (xx)
GR (1) GR76054B (xx)
HK (1) HK23590A (xx)
IE (1) IE52907B1 (xx)
IL (1) IL64981A (xx)
IT (1) IT1148130B (xx)
LU (1) LU84036A1 (xx)
NL (2) NL192453A (xx)
NZ (1) NZ199869A (xx)
PH (1) PH19765A (xx)
PL (1) PL235508A1 (xx)
SE (1) SE452767B (xx)
ZA (1) ZA82674B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG46664A1 (en) * 1985-08-16 1990-02-15 Druzhestven N Izsledovatelski Method for preparing of 6- /d (-)- alpha- (4- ethyl- 2, 3- dioxo- 1- piperazine carbonylamino)- phenylacetamido/- penicillanic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087424A (en) * 1974-05-09 1978-05-02 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
US4112090A (en) * 1974-05-09 1978-09-05 Toyama Chemical Co., Ltd. Novel penicillins and cephalosporins and process for producing the same
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same

Also Published As

Publication number Publication date
BE892586A (fr) 1982-09-22
AU7996482A (en) 1982-10-07
JPS57165391A (en) 1982-10-12
DE3208506C2 (xx) 1991-05-02
FR2502623A1 (fr) 1982-10-01
GR76054B (xx) 1984-08-03
IE52907B1 (en) 1988-04-13
GB2095661A (en) 1982-10-06
DE3208506A1 (de) 1982-10-07
NL8201301A (nl) 1982-10-18
SE452767B (sv) 1987-12-14
NL192453B (nl) 1997-04-01
CH654309A5 (de) 1986-02-14
DK48282A (da) 1982-10-01
DK161079B (da) 1991-05-27
AT381706B (de) 1986-11-25
NL192453A (xx) 1997-10-01
FR2502623B1 (xx) 1984-12-28
IT1148130B (it) 1986-11-26
AU544896B2 (en) 1985-06-20
GB2095661B (en) 1985-02-27
SE8201998L (sv) 1982-10-01
ES509424A0 (es) 1983-06-01
IT8247962A0 (it) 1982-03-10
IE820746L (en) 1982-09-30
LU84036A1 (de) 1982-07-08
NL192453C (nl) 1997-08-04
NZ199869A (en) 1985-07-31
ZA82674B (en) 1982-12-29
DK161079C (da) 1991-11-04
ES8306376A1 (es) 1983-06-01
PL235508A1 (xx) 1982-12-20
HK23590A (en) 1990-04-06
ATA93082A (de) 1986-04-15
JPH0331716B2 (xx) 1991-05-08
IL64981A (en) 1985-11-29
PH19765A (en) 1986-06-27

Similar Documents

Publication Publication Date Title
EP0001133B1 (en) Process for the preparation of 6- d-alpha-amino-(p-hydroxyphenyl)-acetamido penicillanic acid
CA1200239A (en) Process for preparing 6-¬d-(-)-alpha-(4-c1-c4 alkyl- 2,3-dioxo-1-piperazinocarbonyl-amino)- phenylacetamido|penicillanic acid
NO146241B (no) Fremgangsmaate til fremstilling av hetacephalexin eller salter derav.
CN101230057A (zh) 合成苯并咪唑化合物的方法
US4610822A (en) Process for preparing 6-[D(-)-α-(4-C1 -C4)-alkyl-2,3-dioxo-1-piperazinocarbonylamino)phenylacetamido]penicillanic acids
JPH069647A (ja) 新規なセファロスポリン中間体
KR850000611B1 (ko) 6-[d(-)-알파-(4-c₁~c₄)알킬-2,3-디옥소-1-피페라지노 카르보닐아미노)페닐아세트아미도] 페니실란산 제조방법
US4847266A (en) Method for preparing 6-β-halopenicillanic acids
US4237280A (en) Intermediate for cephalosporin type compound
EA008883B1 (ru) Способ получения хирально чистого n-(транс-4-изопропилциклогексилкарбонил)-d-фенилаланина и его кристаллических модификаций
US4433142A (en) Process for the preparation of 7-(2-amino-2-phenylacetamido) cephem derivatives
US6723844B1 (en) Preparation of K-252a
SU359819A1 (ru) Способ получения1,3-дигидро-7-нитро-5-фенил-2н-1,4-
EP0861841B1 (en) Process for producing 2-amino-6-iodopurine
JPH0446175A (ja) ５―ヒドロキシ―３，４―メチレンジオキシ安息香酸誘導体の製造法
SU1011633A1 (ru) Способ получени тетракис-/фенилгидразона или гидразона/циклобутантетраона
CA1049432A (en) Process for the preparation of antibacterial agents
JP3259196B2 (ja) ２−ヒドラジノ−４，６−ジメトキシピリミジンの製造法
US4366098A (en) Process for preparing aminopenicillins
JP3135769B2 (ja) アンジオテンシン変換酵素阻害剤中間体の製造方法
CN111187284A (zh) 一种头孢克洛的制备方法
JPH03148282A (ja) セファロスポラン酸誘導体の製造法
JPH1180072A (ja) 高純度低級飽和脂肪族カルボン酸ヒドロキシルアミンの製造方法
GB2123821A (en) ???-Halogeno diethyl carbonates and their use in the preparation of antibiotics
JPH10139751A (ja) ２−ｎ−アルコキシカルボニル−２，３−ジアミノプロピオン酸の製造方法

Legal Events

Date Code Title Description
MKEX Expiry