CA1196631A - Process for the preparation of 1,4:3,6-dianhydro-d- glucitol 5-nitrate - Google Patents
Process for the preparation of 1,4:3,6-dianhydro-d- glucitol 5-nitrateInfo
- Publication number
- CA1196631A CA1196631A CA000381990A CA381990A CA1196631A CA 1196631 A CA1196631 A CA 1196631A CA 000381990 A CA000381990 A CA 000381990A CA 381990 A CA381990 A CA 381990A CA 1196631 A CA1196631 A CA 1196631A
- Authority
- CA
- Canada
- Prior art keywords
- glucitol
- dianhydro
- nitrate
- acetate
- process according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP3028873.4 | 1980-07-30 | ||
| DE3028873A DE3028873C2 (de) | 1980-07-30 | 1980-07-30 | Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1196631A true CA1196631A (en) | 1985-11-12 |
Family
ID=6108470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000381990A Expired CA1196631A (en) | 1980-07-30 | 1981-07-17 | Process for the preparation of 1,4:3,6-dianhydro-d- glucitol 5-nitrate |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4431829A (enExample) |
| EP (1) | EP0045076B1 (enExample) |
| JP (1) | JPS5753489A (enExample) |
| AT (1) | ATE4458T1 (enExample) |
| CA (1) | CA1196631A (enExample) |
| CS (1) | CS228147B2 (enExample) |
| DD (1) | DD201597A5 (enExample) |
| DE (2) | DE3028873C2 (enExample) |
| ES (1) | ES504449A0 (enExample) |
| FI (1) | FI76344C (enExample) |
| HU (1) | HU189526B (enExample) |
| IL (1) | IL63464A (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3102947A1 (de) * | 1981-01-29 | 1982-09-02 | Heinrich Mack Nachf., 7918 Illertissen | Verfahren zur herstellung von isosorbid-5-nitrat |
| DE3117612A1 (de) * | 1981-05-05 | 1982-11-25 | Cassella Ag, 6000 Frankfurt | Verfahren zur herstellung von isosorbid-5-nitrat |
| DE3124410A1 (de) * | 1981-06-22 | 1983-01-05 | Heinrich Mack Nachf., 7918 Illertissen | Verfahren zur herstellung von isosorbid-2-nitrat |
| DE3128102A1 (de) * | 1981-07-16 | 1983-02-03 | Cassella Ag, 6000 Frankfurt | Verfahren zur herstellung von isosorbid-2-acylaten |
| JPS5818385A (ja) * | 1981-07-27 | 1983-02-02 | Toa Eiyou Kagaku Kogyo Kk | イソソルビド−5−ニトレ−トの製造法 |
| DE3229412A1 (de) * | 1982-08-06 | 1984-02-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von dianhydrohexitol-gemischen aus hexitolen, dianhydro-idit enthaltende dianhydro-hexitol-gemischen und ihre verwendung zur herstellung von polymeren |
| DE4410997A1 (de) * | 1994-03-30 | 1995-10-26 | Isis Pharma Gmbh | Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen |
| DE19726812A1 (de) * | 1997-06-25 | 1999-01-07 | Isis Pharma Gmbh | Neue Derivate des Pentaerythrits, deren Herstellung und Verwendung sowie Intermediate zur Synthese derselben |
| DE102008050597A1 (de) | 2008-10-09 | 2010-04-15 | Actavis Deutschland Gmbh & Co. Kg | Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz |
| CN106061979B (zh) * | 2013-12-19 | 2018-09-28 | 阿彻丹尼尔斯米德兰德公司 | 乙二醇酰化的增强的区域选择性 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3886186A (en) * | 1971-04-29 | 1975-05-27 | American Home Prod | Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol |
| US4065488A (en) * | 1977-02-24 | 1977-12-27 | American Home Products Corporation | Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate |
| DE2903927C2 (de) * | 1979-02-02 | 1981-03-12 | Sanol Schwarz-Monheim Gmbh, 4019 Monheim | Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat |
-
1980
- 1980-07-30 DE DE3028873A patent/DE3028873C2/de not_active Expired
-
1981
- 1981-06-24 US US06/276,773 patent/US4431829A/en not_active Expired - Lifetime
- 1981-07-17 CA CA000381990A patent/CA1196631A/en not_active Expired
- 1981-07-25 EP EP81105882A patent/EP0045076B1/de not_active Expired
- 1981-07-25 AT AT81105882T patent/ATE4458T1/de not_active IP Right Cessation
- 1981-07-25 DE DE8181105882T patent/DE3160767D1/de not_active Expired
- 1981-07-27 DD DD81232126A patent/DD201597A5/de unknown
- 1981-07-28 JP JP56117219A patent/JPS5753489A/ja active Granted
- 1981-07-29 HU HU812216A patent/HU189526B/hu unknown
- 1981-07-29 FI FI812374A patent/FI76344C/fi not_active IP Right Cessation
- 1981-07-29 CS CS815771A patent/CS228147B2/cs unknown
- 1981-07-29 IL IL63464A patent/IL63464A/xx not_active IP Right Cessation
- 1981-07-30 ES ES504449A patent/ES504449A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8205805A1 (es) | 1982-08-16 |
| JPH0250908B2 (enExample) | 1990-11-05 |
| FI76344C (fi) | 1988-10-10 |
| ES504449A0 (es) | 1982-08-16 |
| EP0045076A1 (de) | 1982-02-03 |
| DD201597A5 (de) | 1983-07-27 |
| IL63464A0 (en) | 1981-10-30 |
| US4431829A (en) | 1984-02-14 |
| EP0045076B1 (de) | 1983-08-17 |
| DE3160767D1 (en) | 1983-09-22 |
| FI812374L (fi) | 1982-01-31 |
| HU189526B (en) | 1986-07-28 |
| CS228147B2 (en) | 1984-05-14 |
| DE3028873A1 (de) | 1982-02-11 |
| DE3028873C2 (de) | 1983-10-27 |
| FI76344B (fi) | 1988-06-30 |
| IL63464A (en) | 1985-02-28 |
| ATE4458T1 (de) | 1983-09-15 |
| JPS5753489A (en) | 1982-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |