CA1164456A - Process for the preparation of the 1-(4-chloro- benzoyl)-5-methoxy-2-methyl-3-indolyl- acetohydroxamic acid - Google Patents

Process for the preparation of the 1-(4-chloro- benzoyl)-5-methoxy-2-methyl-3-indolyl- acetohydroxamic acid

Info

Publication number
CA1164456A
CA1164456A CA000398632A CA398632A CA1164456A CA 1164456 A CA1164456 A CA 1164456A CA 000398632 A CA000398632 A CA 000398632A CA 398632 A CA398632 A CA 398632A CA 1164456 A CA1164456 A CA 1164456A
Authority
CA
Canada
Prior art keywords
methyl
indolyl
formula
methoxy
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000398632A
Other languages
English (en)
French (fr)
Inventor
Ugo Chiodoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unibios SpA
Original Assignee
Unibios SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unibios SpA filed Critical Unibios SpA
Application granted granted Critical
Publication of CA1164456A publication Critical patent/CA1164456A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000398632A 1981-04-03 1982-03-17 Process for the preparation of the 1-(4-chloro- benzoyl)-5-methoxy-2-methyl-3-indolyl- acetohydroxamic acid Expired CA1164456A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20918A/81 1981-04-03
IT20918/81A IT1144692B (it) 1981-04-03 1981-04-03 Nuovo procedimento per la preparazione dell'acido 1-p-clorobenzoil-2-metil-5-metossi-2-indolacetoidrossammico

Publications (1)

Publication Number Publication Date
CA1164456A true CA1164456A (en) 1984-03-27

Family

ID=11174057

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000398632A Expired CA1164456A (en) 1981-04-03 1982-03-17 Process for the preparation of the 1-(4-chloro- benzoyl)-5-methoxy-2-methyl-3-indolyl- acetohydroxamic acid

Country Status (11)

Country Link
US (1) US4455432A (en, 2012)
JP (1) JPS57176955A (en, 2012)
KR (1) KR860000649B1 (en, 2012)
BE (1) BE892645A (en, 2012)
CA (1) CA1164456A (en, 2012)
DE (1) DE3211663A1 (en, 2012)
ES (1) ES8302654A1 (en, 2012)
FR (1) FR2503154A1 (en, 2012)
GB (1) GB2097388B (en, 2012)
IT (1) IT1144692B (en, 2012)
NL (1) NL8201420A (en, 2012)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59204172A (ja) * 1983-04-28 1984-11-19 Kowa Co アセメタシンの製造法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2397508A (en) * 1943-05-29 1946-04-02 Standard Oil Co Hydroxamic acids
US2785191A (en) * 1952-07-03 1957-03-12 Ciba Pharm Prod Inc Acylmercapto-alkylamines and process for the manufacture thereof
FR1579495A (en, 2012) * 1968-01-22 1969-08-29
IT1036004B (it) * 1968-05-21 1979-10-30 Abc Ist Biolog Chem Spa Acidt 3 indolil adetoidrossamici
DE2008332C3 (de) * 1970-02-23 1980-05-22 Istituto Biologico Chemioterapico Abc S.P.A., Turin (Italien) 2-Methyl-S-methoxy-3-indolylacetohydroxamsäuren, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2413125C2 (de) * 1974-03-15 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Indolylacetylaminosäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneipräparate
US4186133A (en) * 1978-02-23 1980-01-29 Istituto Biologico Chemioterapico "Abc" S.P.A. Process for the preparation of an indole-3-acetohydroxamic acid

Also Published As

Publication number Publication date
ES511037A0 (es) 1983-02-01
KR860000649B1 (ko) 1986-05-28
IT1144692B (it) 1986-10-29
JPS57176955A (en) 1982-10-30
US4455432A (en) 1984-06-19
BE892645A (nl) 1982-07-16
FR2503154A1 (fr) 1982-10-08
NL8201420A (nl) 1982-11-01
FR2503154B1 (en, 2012) 1985-05-17
GB2097388B (en) 1985-01-03
KR830010068A (ko) 1983-12-26
IT8120918A0 (it) 1981-04-03
DE3211663C2 (en, 2012) 1990-12-13
GB2097388A (en) 1982-11-03
ES8302654A1 (es) 1983-02-01
JPH0149151B2 (en, 2012) 1989-10-23
DE3211663A1 (de) 1982-10-21

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