CA1073455A - (aroyl-2'eth-1'yl)-1 (acetamido-4"piperazin-1"methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation_______ - Google Patents

(aroyl-2'eth-1'yl)-1 (acetamido-4"piperazin-1"methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation_______

Info

Publication number
CA1073455A
CA1073455A CA243,226A CA243226A CA1073455A CA 1073455 A CA1073455 A CA 1073455A CA 243226 A CA243226 A CA 243226A CA 1073455 A CA1073455 A CA 1073455A
Authority
CA
Canada
Prior art keywords
group
formula
carbon atoms
alpha
alkyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA243,226A
Other languages
English (en)
French (fr)
Other versions
CA243226S (en
Inventor
Thierry Imbert
Claude Fauran
Guy Raynaud
Michel Turin
Nicole Dorme
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7500724A external-priority patent/FR2297045A1/fr
Priority claimed from FR7537297A external-priority patent/FR2333510A2/fr
Application filed by Delalande SA filed Critical Delalande SA
Application granted granted Critical
Publication of CA1073455A publication Critical patent/CA1073455A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA243,226A 1975-01-10 1976-01-08 (aroyl-2'eth-1'yl)-1 (acetamido-4"piperazin-1"methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation_______ Expired CA1073455A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7500724A FR2297045A1 (fr) 1975-01-10 1975-01-10 Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse
FR7537297A FR2333510A2 (fr) 1975-12-05 1975-12-05 Nouveaux (aroyl-2' eth-1 yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation

Publications (1)

Publication Number Publication Date
CA1073455A true CA1073455A (fr) 1980-03-11

Family

ID=26218682

Family Applications (1)

Application Number Title Priority Date Filing Date
CA243,226A Expired CA1073455A (fr) 1975-01-10 1976-01-08 (aroyl-2'eth-1'yl)-1 (acetamido-4"piperazin-1"methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation_______

Country Status (13)

Country Link
JP (1) JPS6020386B2 (enExample)
AU (1) AU509084B2 (enExample)
CA (1) CA1073455A (enExample)
CH (1) CH612675A5 (enExample)
DE (1) DE2557446C2 (enExample)
ES (1) ES444064A1 (enExample)
GB (1) GB1487128A (enExample)
IT (1) IT1062803B (enExample)
LU (1) LU74043A1 (enExample)
MX (1) MX3428E (enExample)
NL (1) NL7600224A (enExample)
SE (1) SE421527B (enExample)
SU (1) SU651701A3 (enExample)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190439B1 (enExample) * 1972-07-06 1975-06-20 Delalande Sa

Also Published As

Publication number Publication date
DE2557446C2 (de) 1984-11-29
IT1062803B (it) 1985-02-11
GB1487128A (en) 1977-09-28
SU651701A3 (ru) 1979-03-05
AU1011776A (en) 1977-07-14
AU509084B2 (en) 1980-04-17
CH612675A5 (en) 1979-08-15
JPS51131885A (en) 1976-11-16
NL7600224A (nl) 1976-07-13
LU74043A1 (enExample) 1976-11-11
ES444064A1 (es) 1977-08-16
SE421527B (sv) 1982-01-04
DE2557446A1 (de) 1976-07-15
JPS6020386B2 (ja) 1985-05-21
SE7600116L (sv) 1976-07-12
MX3428E (es) 1980-11-21

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