GB1487128A - 1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation - Google Patents

1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation

Info

Publication number
GB1487128A
GB1487128A GB51396/75A GB5139675A GB1487128A GB 1487128 A GB1487128 A GB 1487128A GB 51396/75 A GB51396/75 A GB 51396/75A GB 5139675 A GB5139675 A GB 5139675A GB 1487128 A GB1487128 A GB 1487128A
Authority
GB
United Kingdom
Prior art keywords
methyl
benzimidazoles
aroyl
piperazin
carbamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB51396/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7500724A external-priority patent/FR2297045A1/en
Priority claimed from FR7537297A external-priority patent/FR2333510A2/en
Application filed by Delalande SA filed Critical Delalande SA
Publication of GB1487128A publication Critical patent/GB1487128A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB51396/75A 1975-01-10 1975-12-16 1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation Expired GB1487128A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7500724A FR2297045A1 (en) 1975-01-10 1975-01-10 NEW (AROYL-2 'ETH-1' YL) -1 (ACETAMIDO-4 '' PIPERAZIN-1 '' YL METHYL) -2 BENZIMIDAZOLES WITH GASTRIC AND ANTIULCEROUS ANTI-SECRETORY PROPERTIES
FR7537297A FR2333510A2 (en) 1975-12-05 1975-12-05 1-Aroylethyl 2-piperazinomethyl benzimidazoles - useful eg for treatment of ulcers, asthma, hypertension, oedemand pain

Publications (1)

Publication Number Publication Date
GB1487128A true GB1487128A (en) 1977-09-28

Family

ID=26218682

Family Applications (1)

Application Number Title Priority Date Filing Date
GB51396/75A Expired GB1487128A (en) 1975-01-10 1975-12-16 1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation

Country Status (13)

Country Link
JP (1) JPS6020386B2 (en)
AU (1) AU509084B2 (en)
CA (1) CA1073455A (en)
CH (1) CH612675A5 (en)
DE (1) DE2557446C2 (en)
ES (1) ES444064A1 (en)
GB (1) GB1487128A (en)
IT (1) IT1062803B (en)
LU (1) LU74043A1 (en)
MX (1) MX3428E (en)
NL (1) NL7600224A (en)
SE (1) SE421527B (en)
SU (1) SU651701A3 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190439B1 (en) * 1972-07-06 1975-06-20 Delalande Sa

Also Published As

Publication number Publication date
ES444064A1 (en) 1977-08-16
CA1073455A (en) 1980-03-11
DE2557446C2 (en) 1984-11-29
JPS6020386B2 (en) 1985-05-21
SE421527B (en) 1982-01-04
CH612675A5 (en) 1979-08-15
AU509084B2 (en) 1980-04-17
MX3428E (en) 1980-11-21
AU1011776A (en) 1977-07-14
JPS51131885A (en) 1976-11-16
IT1062803B (en) 1985-02-11
LU74043A1 (en) 1976-11-11
NL7600224A (en) 1976-07-13
DE2557446A1 (en) 1976-07-15
SU651701A3 (en) 1979-03-05
SE7600116L (en) 1976-07-12

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee