FR2297045A1 - Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse - Google Patents

Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse

Info

Publication number
FR2297045A1
FR2297045A1 FR7500724A FR7500724A FR2297045A1 FR 2297045 A1 FR2297045 A1 FR 2297045A1 FR 7500724 A FR7500724 A FR 7500724A FR 7500724 A FR7500724 A FR 7500724A FR 2297045 A1 FR2297045 A1 FR 2297045A1
Authority
FR
France
Prior art keywords
antiulcerous
benzimidazoles
eth
aroyl
acetamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7500724A
Other languages
English (en)
Other versions
FR2297045B1 (fr
Inventor
Claude Fauran
Michel Turin
Thierry Imbert
Guy Raynaud
Nicole Dorm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7500724A priority Critical patent/FR2297045A1/fr
Priority to BE162695A priority patent/BE836579A/fr
Priority to GB51396/75A priority patent/GB1487128A/en
Priority to ZA757839A priority patent/ZA757839B/xx
Priority to LU74043A priority patent/LU74043A1/xx
Priority to DE2557446A priority patent/DE2557446C2/de
Priority to US05/643,490 priority patent/US4072682A/en
Priority to ES444064A priority patent/ES444064A1/es
Priority to MX001645U priority patent/MX3428E/es
Priority to CH12876A priority patent/CH612675A5/xx
Priority to SE7600116A priority patent/SE421527B/xx
Priority to SU762305959A priority patent/SU651701A3/ru
Priority to CA243,226A priority patent/CA1073455A/fr
Priority to AU10117/76A priority patent/AU509084B2/en
Priority to JP761833A priority patent/JPS6020386B2/ja
Priority to IT67044/76A priority patent/IT1062803B/it
Priority to NL7600224A priority patent/NL7600224A/xx
Publication of FR2297045A1 publication Critical patent/FR2297045A1/fr
Priority to US05/855,419 priority patent/US4104384A/en
Application granted granted Critical
Publication of FR2297045B1 publication Critical patent/FR2297045B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7500724A 1975-01-10 1975-01-10 Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse Granted FR2297045A1 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR7500724A FR2297045A1 (fr) 1975-01-10 1975-01-10 Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse
BE162695A BE836579A (fr) 1975-01-10 1975-12-12 Nouveaux (aroyl - 2' eth-1 yl)-1 (acetamido -4" piperazin - 1" yl methyl ) - 2 benzimidazoles, leur application en therapeutique et leur procede de preparation
GB51396/75A GB1487128A (en) 1975-01-10 1975-12-16 1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation
ZA757839A ZA757839B (en) 1975-01-10 1975-12-17 New 1-(2'-aroyl eth-1'yl)2-(4'-acetamido piperazine-1'yl methyl)benzimidazoles,their thereapeutical applications and method for their preparation
LU74043A LU74043A1 (fr) 1975-01-10 1975-12-18
DE2557446A DE2557446C2 (de) 1975-01-10 1975-12-19 1-(2'-Aroyl-äth-1'-yl)-2-(4''-acetamido-piperazin-1''-yl-methyl)-benzimidazole, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US05/643,490 US4072682A (en) 1975-01-10 1975-12-22 New 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their therapeutical applications and method for their preparation
ES444064A ES444064A1 (es) 1975-01-10 1976-01-03 Procedimiento de preparacion de nuevos (aroil-2'-et-1'-il)- 1-(acetamido-4"-piperazin-1"-il-metil)-2-bencimidazoles.
MX001645U MX3428E (es) 1975-01-10 1976-01-06 Procedimiento para la preparacion de (aroil-2' et-1'il)-1 (acetamido-4" piperazin-1" il metil)-2 benzimidazoles
CH12876A CH612675A5 (en) 1975-01-10 1976-01-07 Process for the preparation of new 1-(2'-aroyl-1'-ethyl)-2-(4''-acetamido-1''-piperazinylmethyl)benzimidazo les
SU762305959A SU651701A3 (ru) 1975-01-10 1976-01-08 Способ получени производных бензимидазола
CA243,226A CA1073455A (fr) 1975-01-10 1976-01-08 (aroyl-2'eth-1'yl)-1 (acetamido-4"piperazin-1"methyl)-2 benzimidazoles, leur application en therapeutique et leur procede de preparation_______
AU10117/76A AU509084B2 (en) 1975-01-10 1976-01-08 l-(2'aroyl eth-1' yl)-2-(4-acetamido piperazine-l-yl methyl) benzimidoles
JP761833A JPS6020386B2 (ja) 1975-01-10 1976-01-08 １−（２′−アロイルエチル−１′）−２−（４″−アセトアミドピペラジン−１″−イルメチル）ベンズイミダゾ−ル類，それを含有する医薬及びその製法
SE7600116A SE421527B (sv) 1975-01-10 1976-01-08 Analogiforfarande for framstellninh av 1-(2'-aroyl-1'-etyl)-2-(4"-acetamido-1"-piperazinylmetyl)-bensimidazoler
IT67044/76A IT1062803B (it) 1975-01-10 1976-01-09 Aroil 2 et 1 il..1..acetammido 4 piperazin 1 il metil..2 benzimidazoli..loro procedimento di preparazione e loro procedimento in terapia
NL7600224A NL7600224A (nl) 1975-01-10 1976-01-09 Werkwijze voor de bereiding van nieuwe benzimida- zoolverbindingen, alsmede hun toepassing voor de bereiding van een geneesmiddel.
US05/855,419 US4104384A (en) 1975-01-10 1977-11-28 1-(2'-Aroyl eth-1'yl) 2-(4"-acetamido piperazine-1"yl methyl) benzimidazoles and their therapeutical applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7500724A FR2297045A1 (fr) 1975-01-10 1975-01-10 Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse

Publications (2)

Publication Number Publication Date
FR2297045A1 true FR2297045A1 (fr) 1976-08-06
FR2297045B1 FR2297045B1 (fr) 1978-07-28

Family

ID=9149634

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7500724A Granted FR2297045A1 (fr) 1975-01-10 1975-01-10 Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse

Country Status (4)

Country Link
US (1) US4072682A (fr)
BE (1) BE836579A (fr)
FR (1) FR2297045A1 (fr)
ZA (1) ZA757839B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2496661A1 (fr) * 1980-12-23 1982-06-25 Kyorin Seiyaku Kk Derives de substitution en 1,4 de la piperazine, leur preparation et medicament contenant ces substances

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104384A (en) * 1975-01-10 1978-08-01 Delalande S.A. 1-(2'-Aroyl eth-1'yl) 2-(4"-acetamido piperazine-1"yl methyl) benzimidazoles and their therapeutical applications

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2014525A1 (fr) * 1968-07-06 1970-04-17 Delalande Sa
FR2190439A1 (fr) * 1972-07-06 1974-02-01 Delalande Sa

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2935514A (en) * 1960-05-03 Benzimidazoles
US3325356A (en) * 1965-08-20 1967-06-13 Merck & Co Inc Compositions and method for treating helminthiasis
US3505354A (en) * 1967-05-18 1970-04-07 Geigy Chem Corp 2-methyl-3-p-halobenzoylindole-n-aliphatic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2014525A1 (fr) * 1968-07-06 1970-04-17 Delalande Sa
FR2190439A1 (fr) * 1972-07-06 1974-02-01 Delalande Sa

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2496661A1 (fr) * 1980-12-23 1982-06-25 Kyorin Seiyaku Kk Derives de substitution en 1,4 de la piperazine, leur preparation et medicament contenant ces substances

Also Published As

Publication number Publication date
US4072682A (en) 1978-02-07
FR2297045B1 (fr) 1978-07-28
BE836579A (fr) 1976-06-14
ZA757839B (en) 1976-11-24

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