CA1073452A - 8.alpha.-ERGOLINE I COMPOUNDS - Google Patents

8.alpha.-ERGOLINE I COMPOUNDS

Info

Publication number
CA1073452A
CA1073452A CA231,773A CA231773A CA1073452A CA 1073452 A CA1073452 A CA 1073452A CA 231773 A CA231773 A CA 231773A CA 1073452 A CA1073452 A CA 1073452A
Authority
CA
Canada
Prior art keywords
carbon atoms
methyl
ergoline
alpha
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA231,773A
Other languages
English (en)
French (fr)
Inventor
Peter Stutz
Theodor Fehr
Paul Stadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH998374A external-priority patent/CH605936A5/de
Priority claimed from CH1103174A external-priority patent/CH605938A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1073452A publication Critical patent/CA1073452A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA231,773A 1974-07-19 1975-07-18 8.alpha.-ERGOLINE I COMPOUNDS Expired CA1073452A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH998374A CH605936A5 (en) 1974-07-19 1974-07-19 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs
CH1103174A CH605938A5 (en) 1974-08-13 1974-08-13 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs

Publications (1)

Publication Number Publication Date
CA1073452A true CA1073452A (en) 1980-03-11

Family

ID=25705648

Family Applications (1)

Application Number Title Priority Date Filing Date
CA231,773A Expired CA1073452A (en) 1974-07-19 1975-07-18 8.alpha.-ERGOLINE I COMPOUNDS

Country Status (17)

Country Link
JP (1) JPS5134199A (ja)
AU (1) AU505314B2 (ja)
CA (1) CA1073452A (ja)
DD (1) DD118635A5 (ja)
DE (1) DE2530577A1 (ja)
DK (2) DK143902C (ja)
ES (1) ES439548A1 (ja)
FI (1) FI61188C (ja)
FR (1) FR2282889A1 (ja)
GB (3) GB1517973A (ja)
HK (2) HK56980A (ja)
IE (1) IE41426B1 (ja)
IL (1) IL47735A (ja)
MY (2) MY8100217A (ja)
NL (1) NL7508416A (ja)
NO (1) NO752493L (ja)
PH (1) PH16594A (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573621A (en) * 1976-01-02 1980-08-28 Sandoz Ltd Acylated 6-methyl-8a-amino-ergoline i compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
IT1064473B (it) * 1976-11-24 1985-02-18 Simes Sulfamoil derivati dell'8-beta-amminometilergolina
WO1982000463A1 (en) * 1980-07-25 1982-02-18 Ag Sandoz Ergoline derivatives,method for their preparation,pharmaceutical compositions containing them and their therapeutic application
BE889713A (fr) * 1980-07-25 1982-01-25 Sandoz Sa Nouveaux derives de l'ergoline, leur preparation et leur application comme medicaments
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
JPS58174081A (ja) * 1982-04-05 1983-10-13 Mitsubishi Heavy Ind Ltd 船内機関室通風装置
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
HUT45248A (en) * 1986-01-24 1988-06-28 Sandoz Ag Process for producing 8alpha-(acylamino)-ergoline derivatives and pharmaceuticals comprising such compounds
AT392945B (de) * 1988-06-27 1991-07-10 Gerhard Mader Ges M B H Ing Lager- und transportbehaelter fuer schuettgueter und lose materialien
DE4033496A1 (de) * 1990-10-20 1992-04-23 Sandoz Ag Neue ergolinderivate, ihre herstellung und verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
FR1360618A (fr) * 1963-06-17 1964-05-08 Sandoz Sa Nouveaux uréthanes de la série lysergique et leur préparation
CH507248A (de) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von D-6-Methylergolin(I)ylessigsäure
NL6818658A (ja) * 1968-01-18 1969-07-22
AR206772A1 (es) * 1972-07-21 1976-08-23 Lilly Co Eli Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina

Also Published As

Publication number Publication date
NL7508416A (nl) 1976-01-21
IL47735A (en) 1979-11-30
FI61188C (fi) 1982-06-10
DD118635A5 (ja) 1976-03-12
AU8316275A (en) 1977-01-20
NO752493L (ja) 1976-01-20
MY8100217A (en) 1981-12-31
DK143902B (da) 1981-10-26
DK298980A (da) 1980-07-10
IE41426B1 (en) 1980-01-02
DK145542C (da) 1983-05-02
IE41426L (en) 1976-01-19
HK56980A (en) 1980-10-16
PH16594A (en) 1983-11-22
FI752011A (ja) 1976-01-20
IL47735A0 (en) 1975-10-15
FR2282889B1 (ja) 1979-08-10
DK313175A (da) 1976-01-20
ES439548A1 (es) 1977-06-16
GB1517973A (en) 1978-07-19
DK143902C (da) 1982-04-13
JPS5134199A (ja) 1976-03-23
GB1517972A (en) 1978-07-19
GB1517971A (en) 1978-07-19
DK145542B (da) 1982-12-06
DE2530577C2 (ja) 1990-11-08
DE2530577A1 (de) 1976-01-29
HK56880A (en) 1980-10-16
AU505314B2 (en) 1979-11-15
FI61188B (fi) 1982-02-26
FR2282889A1 (fr) 1976-03-26
MY8100215A (en) 1981-12-31

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