CA1071201A - Oxime ethers and process for the preparation thereof - Google Patents

Oxime ethers and process for the preparation thereof

Info

Publication number
CA1071201A
CA1071201A CA245,043A CA245043A CA1071201A CA 1071201 A CA1071201 A CA 1071201A CA 245043 A CA245043 A CA 245043A CA 1071201 A CA1071201 A CA 1071201A
Authority
CA
Canada
Prior art keywords
moles
general formula
oxime
specified
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA245,043A
Other languages
English (en)
French (fr)
Inventor
Zoltan Budai
Aranka Lay
Tibor Mezei
Katalin Grasser
Eniko Szirt
Ibolya Kosoczky
Lujza E. Petocz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/652,806 external-priority patent/US4083978A/en
Priority to DK32576A priority Critical patent/DK149043C/da
Priority to GB3176/76A priority patent/GB1493222A/en
Priority to US05/652,806 priority patent/US4083978A/en
Priority to FR7602460A priority patent/FR2339397A1/fr
Priority to FI760218A priority patent/FI65615C/fi
Priority to SE7600969A priority patent/SE410733B/xx
Priority to NLAANVRAGE7600945,A priority patent/NL180585C/xx
Priority to BE164044A priority patent/BE838213A/xx
Priority to CA245,043A priority patent/CA1071201A/en
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to JP1273676A priority patent/JPS5295643A/ja
Priority to AT813776A priority patent/AT342019B/de
Priority to AT125076A priority patent/AT339276B/de
Priority claimed from AT125076A external-priority patent/AT339276B/de
Priority to CH223676A priority patent/CH626058A5/de
Priority to DD191525A priority patent/DD125547A5/xx
Priority to DE2609017A priority patent/DE2609017C3/de
Priority to US05/749,399 priority patent/US4077999A/en
Publication of CA1071201A publication Critical patent/CA1071201A/en
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA245,043A 1976-01-27 1976-02-04 Oxime ethers and process for the preparation thereof Expired CA1071201A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
DK32576A DK149043C (da) 1976-01-27 1976-01-27 Analogifremgangsmaade til fremstilling af 2-benzal- eller 2-benzyl-1-(aminoalkoxyimino)-cykloalkaner eller salte eller kvaternaere ammoniumderivater deraf
GB3176/76A GB1493222A (en) 1976-01-27 1976-01-27 Cycloalkanone oxime ethers and process for the preparation thereof
US05/652,806 US4083978A (en) 1976-01-27 1976-01-27 Oxime ethers
FR7602460A FR2339397A1 (fr) 1976-01-27 1976-01-29 Nouveaux ethers d'oximes, procede de preparation de ceux-ci et medicaments les contenant
FI760218A FI65615C (fi) 1976-01-27 1976-01-29 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara oximetrar
SE7600969A SE410733B (sv) 1976-01-27 1976-01-29 Sett att framstella vissa angivna oximetrar
NLAANVRAGE7600945,A NL180585C (nl) 1976-01-27 1976-01-30 Werkwijze voor de bereiding van oxim-ethers, alsmede werkwijze voor de bereiding of vervaardiging van farmaceutische preparaten die deze bevatten.
BE164044A BE838213A (fr) 1976-01-27 1976-02-03 Nouveaux ethers d'oximes, procede de preparation de ceux-ci et medicaments les contenant
CA245,043A CA1071201A (en) 1976-01-27 1976-02-04 Oxime ethers and process for the preparation thereof
JP1273676A JPS5295643A (en) 1976-01-27 1976-02-07 Oxim ether and process for preparing same
AT813776A AT342019B (de) 1976-01-27 1976-02-23 Verfahren zur herstellung von basischen cycloalkanonoximathern und deren saureadditionssalzen
AT125076A AT339276B (de) 1976-01-27 1976-02-23 Verfahren zur herstellung von basischen cycloalkanonoximathern und deren saureadditionssalzen
CH223676A CH626058A5 (en) 1976-01-27 1976-02-24 Process for the preparation of basic oxime ethers
DD191525A DD125547A5 (xx) 1976-01-27 1976-02-26
DE2609017A DE2609017C3 (de) 1976-01-27 1976-03-04 Basische Oximäther, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzeimittel
US05/749,399 US4077999A (en) 1976-01-27 1976-12-10 Novel oxime ethers

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
DK32576A DK149043C (da) 1976-01-27 1976-01-27 Analogifremgangsmaade til fremstilling af 2-benzal- eller 2-benzyl-1-(aminoalkoxyimino)-cykloalkaner eller salte eller kvaternaere ammoniumderivater deraf
GB3176/76A GB1493222A (en) 1976-01-27 1976-01-27 Cycloalkanone oxime ethers and process for the preparation thereof
US05/652,806 US4083978A (en) 1976-01-27 1976-01-27 Oxime ethers
FR7602460A FR2339397A1 (fr) 1976-01-27 1976-01-29 Nouveaux ethers d'oximes, procede de preparation de ceux-ci et medicaments les contenant
FI760218A FI65615C (fi) 1976-01-27 1976-01-29 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara oximetrar
SE7600969A SE410733B (sv) 1976-01-27 1976-01-29 Sett att framstella vissa angivna oximetrar
NLAANVRAGE7600945,A NL180585C (nl) 1976-01-27 1976-01-30 Werkwijze voor de bereiding van oxim-ethers, alsmede werkwijze voor de bereiding of vervaardiging van farmaceutische preparaten die deze bevatten.
BE164044A BE838213A (fr) 1976-01-27 1976-02-03 Nouveaux ethers d'oximes, procede de preparation de ceux-ci et medicaments les contenant
CA245,043A CA1071201A (en) 1976-01-27 1976-02-04 Oxime ethers and process for the preparation thereof
JP1273676A JPS5295643A (en) 1976-01-27 1976-02-07 Oxim ether and process for preparing same
AT813776A AT342019B (de) 1976-01-27 1976-02-23 Verfahren zur herstellung von basischen cycloalkanonoximathern und deren saureadditionssalzen
AT125076A AT339276B (de) 1976-01-27 1976-02-23 Verfahren zur herstellung von basischen cycloalkanonoximathern und deren saureadditionssalzen
CH223676A CH626058A5 (en) 1976-01-27 1976-02-24 Process for the preparation of basic oxime ethers
DD191525A DD125547A5 (xx) 1976-01-27 1976-02-26
DE2609017A DE2609017C3 (de) 1976-01-27 1976-03-04 Basische Oximäther, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzeimittel
US05/749,399 US4077999A (en) 1976-01-27 1976-12-10 Novel oxime ethers

Publications (1)

Publication Number Publication Date
CA1071201A true CA1071201A (en) 1980-02-05

Family

ID=27585558

Family Applications (1)

Application Number Title Priority Date Filing Date
CA245,043A Expired CA1071201A (en) 1976-01-27 1976-02-04 Oxime ethers and process for the preparation thereof

Country Status (13)

Country Link
JP (1) JPS5295643A (xx)
AT (1) AT342019B (xx)
BE (1) BE838213A (xx)
CA (1) CA1071201A (xx)
CH (1) CH626058A5 (xx)
DD (1) DD125547A5 (xx)
DE (1) DE2609017C3 (xx)
DK (1) DK149043C (xx)
FI (1) FI65615C (xx)
FR (1) FR2339397A1 (xx)
GB (1) GB1493222A (xx)
NL (1) NL180585C (xx)
SE (1) SE410733B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658938A1 (de) * 1976-12-24 1978-07-06 Hoechst Ag Neue basisch substituierte 0-propyloxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU180739B (en) * 1979-07-03 1983-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing basic oxime-ethers
FR2518090A1 (fr) * 1981-12-11 1983-06-17 Univablot Ethers d'oximes a-b insatures, leur procede de preparation et leur utilisation comme medicament
HU190387B (en) * 1982-05-25 1986-08-28 Egyt Gyogyszervegyeszeti Gyar,Hu Process for producing 2-bracket-z-bracket closed-phenyl-methylene-cycloheptane derivatives
HU188250B (en) * 1983-02-08 1986-03-28 Egyt Gyogyszervegyeszeti Gyar,Hu Process for producing of basical oxim-ethers
HU189226B (en) * 1983-02-08 1986-06-30 Egyt Gyogyszervegyeszeti Gyar,Hu Process for producing basic oxime-ethers
HU197205B (en) * 1984-07-10 1989-03-28 Egyt Gyogyszervegyeszeti Gyar Process for production of medical compositions against angine
HU202195B (en) * 1987-12-31 1991-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing new substituted styrene derivatives and medical compositions comprising such compounds
CA2006309C (fr) * 1988-12-29 2001-12-18 Jean Hutt Azolylmethylcyclopentane benzylidene fongicide
HU212415B (en) * 1989-08-25 1996-06-28 Egyt Gyogyszervegyeszeti Gyar Process for producing new cyclic oxym derivatives and pharmaceutical compositions containing them as active components
HUT67314A (en) * 1993-04-09 1995-03-28 Egyt Gyogyszervegyeszeti Gyar Process for prepg. new trisubstituted cykloalkane deriv.s and pharmaceutical compn.s contg. them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3262975A (en) 1963-02-12 1966-07-26 Upjohn Co 1-chloro-3, 4-dihydro 2-naphthaldehyde oxime and ethers thereof
US3937841A (en) 1967-04-05 1976-02-10 U.S. Philips Corporation Treatment of depression
CH512184A (de) 1969-08-06 1971-09-15 Ciba Geigy Ag Verwendung von Cyclohexanon- resp. Cyclohexenon-N-Alkylcarbamoyloximen zur Bekämpfung von Zecken
CA943138A (en) 1969-11-10 1974-03-05 Don R. Baker Certain oxime compositions and their use in controlling fungi
US3928446A (en) 1974-04-11 1975-12-23 Hoffmann La Roche Preparation of 3-oxo-19-nor-{66 {hu 4{b -steroids from 10-{8 3-substituted-alkyl{9 -desasteroids

Also Published As

Publication number Publication date
NL180585B (nl) 1986-10-16
DK149043B (da) 1985-12-30
AT342019B (de) 1978-03-10
SE7600969L (sv) 1977-07-30
DE2609017B2 (de) 1980-10-09
FR2339397A1 (fr) 1977-08-26
DK32576A (da) 1977-07-28
DE2609017A1 (de) 1977-09-08
DD125547A5 (xx) 1977-05-04
ATA813776A (de) 1977-07-15
FI65615C (fi) 1984-06-11
SE410733B (sv) 1979-10-29
CH626058A5 (en) 1981-10-30
DE2609017C3 (de) 1981-05-27
FR2339397B1 (xx) 1979-10-05
NL7600945A (nl) 1977-08-02
BE838213A (fr) 1976-05-28
FI65615B (fi) 1984-02-29
FI760218A (xx) 1977-07-30
JPS5715746B2 (xx) 1982-04-01
GB1493222A (en) 1977-11-30
NL180585C (nl) 1987-03-16
JPS5295643A (en) 1977-08-11
DK149043C (da) 1986-05-26

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Legal Events

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