CA1071192A - 6-METHYL-8.beta.-(-CH2-S-R)ERGOLENE OR ERGOLINE - Google Patents

6-METHYL-8.beta.-(-CH2-S-R)ERGOLENE OR ERGOLINE

Info

Publication number
CA1071192A
CA1071192A CA221,971A CA221971A CA1071192A CA 1071192 A CA1071192 A CA 1071192A CA 221971 A CA221971 A CA 221971A CA 1071192 A CA1071192 A CA 1071192A
Authority
CA
Canada
Prior art keywords
formula
compound
methyl
hetero
nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA221,971A
Other languages
English (en)
French (fr)
Other versions
CA221971S (en
Inventor
Paul Stadler
Peter Stutz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH356374A external-priority patent/CH593972A5/xx
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1071192A publication Critical patent/CA1071192A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA221,971A 1974-03-14 1975-03-13 6-METHYL-8.beta.-(-CH2-S-R)ERGOLENE OR ERGOLINE Expired CA1071192A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH356374A CH593972A5 (ja) 1974-03-14 1974-03-14
CH1013874 1974-07-23

Publications (1)

Publication Number Publication Date
CA1071192A true CA1071192A (en) 1980-02-05

Family

ID=25693324

Family Applications (1)

Application Number Title Priority Date Filing Date
CA221,971A Expired CA1071192A (en) 1974-03-14 1975-03-13 6-METHYL-8.beta.-(-CH2-S-R)ERGOLENE OR ERGOLINE

Country Status (18)

Country Link
JP (1) JPS589111B2 (ja)
AU (1) AU500890B2 (ja)
CA (1) CA1071192A (ja)
DD (1) DD118428A5 (ja)
DE (1) DE2509471A1 (ja)
DK (1) DK141701B (ja)
ES (1) ES435538A1 (ja)
FI (1) FI60865C (ja)
FR (1) FR2263774B1 (ja)
GB (1) GB1497681A (ja)
HK (1) HK8481A (ja)
IE (1) IE41533B1 (ja)
IL (1) IL46809A (ja)
MY (1) MY8100331A (ja)
NL (1) NL7502807A (ja)
NO (1) NO750748L (ja)
PH (1) PH12966A (ja)
SE (1) SE420094B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
JPS5293797A (en) * 1976-01-30 1977-08-06 Sandoz Ag Improvement in organic compound
GB1555751A (en) * 1977-02-02 1979-11-14 Farmaceutici Italia Ergoline deritatives
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
GB2120242A (en) * 1982-04-30 1983-11-30 Erba Farmitalia Ergoline derivatives
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
IT1215261B (it) * 1985-04-05 1990-01-31 Poli Ind Chimica Spa Composizioni farmaceutiche adattivita' antigalattopoietica.
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6818658A (ja) * 1968-01-18 1969-07-22

Also Published As

Publication number Publication date
NO750748L (ja) 1975-09-16
JPS50123698A (ja) 1975-09-29
NL7502807A (nl) 1975-09-16
AU500890B2 (en) 1979-06-07
SE7502469L (ja) 1975-09-15
DK89375A (ja) 1975-09-15
FI60865B (fi) 1981-12-31
HK8481A (en) 1981-03-20
GB1497681A (en) 1978-01-12
IL46809A (en) 1978-04-30
FR2263774A1 (ja) 1975-10-10
IE41533B1 (en) 1980-01-30
DK141701B (da) 1980-05-27
FI750644A (ja) 1975-09-15
IL46809A0 (en) 1975-07-28
IE41533L (en) 1975-09-14
FR2263774B1 (ja) 1978-08-04
ES435538A1 (es) 1977-03-16
FI60865C (fi) 1982-04-13
AU7905775A (en) 1976-09-16
SE420094B (sv) 1981-09-14
JPS589111B2 (ja) 1983-02-18
DD118428A5 (ja) 1976-03-05
DK141701C (ja) 1980-10-20
PH12966A (en) 1979-10-19
MY8100331A (en) 1981-12-31
DE2509471A1 (de) 1975-09-18

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