CA1042797A - Aqueous rafoxanide formulations - Google Patents

Aqueous rafoxanide formulations

Info

Publication number
CA1042797A
CA1042797A CA229,091A CA229091A CA1042797A CA 1042797 A CA1042797 A CA 1042797A CA 229091 A CA229091 A CA 229091A CA 1042797 A CA1042797 A CA 1042797A
Authority
CA
Canada
Prior art keywords
rafoxanide
acid
solution
aqueous
alkali metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA229,091A
Other languages
English (en)
French (fr)
Inventor
Robert J. Nessel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1042797A publication Critical patent/CA1042797A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA229,091A 1974-06-19 1975-06-11 Aqueous rafoxanide formulations Expired CA1042797A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48064574A 1974-06-19 1974-06-19

Publications (1)

Publication Number Publication Date
CA1042797A true CA1042797A (en) 1978-11-21

Family

ID=23908782

Family Applications (1)

Application Number Title Priority Date Filing Date
CA229,091A Expired CA1042797A (en) 1974-06-19 1975-06-11 Aqueous rafoxanide formulations

Country Status (10)

Country Link
JP (1) JPS5821888B2 (it)
BE (1) BE830383A (it)
CA (1) CA1042797A (it)
DE (1) DE2526986A1 (it)
FR (1) FR2275217A1 (it)
GB (1) GB1472385A (it)
IL (1) IL47448A (it)
NL (1) NL184257C (it)
PH (1) PH12304A (it)
ZA (1) ZA753921B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
FR2577437A1 (fr) * 1985-02-21 1986-08-22 Corbiere Jerome Nouveau procede de solubilisation des composes chimiques et les preparations aqueuses ainsi obtenues
GB2247884B (en) * 1990-09-11 1994-05-11 Chanelle Chemicals Ltd Manufacture of a salicylanilide derivative
EP1129713A1 (en) * 2000-02-29 2001-09-05 New Pharma Research Sweden AB Veterinary compositions for the treatment of parasitic diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD92776A (it) *
DE1089510B (de) * 1959-03-23 1960-09-22 Rudolf Reiss Dr Verfahren zur Herstellung waessriger, injizierbarer Loesungen von 2-Methoxy-4-allylphenoxyessigsaeure-N, N-Diaethylamid
DE1209700B (de) * 1964-05-02 1966-01-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung einer wasserloeslichen Zubereitungsform des 3, 5-Dinitro-o-toluamids
NL6816239A (it) * 1967-12-01 1969-06-03

Also Published As

Publication number Publication date
FR2275217B1 (it) 1979-08-17
JPS5821888B2 (ja) 1983-05-04
FR2275217A1 (fr) 1976-01-16
NL184257C (nl) 1989-06-01
GB1472385A (en) 1977-05-04
AU8197375A (en) 1976-12-16
PH12304A (en) 1979-01-16
ZA753921B (en) 1977-01-26
BE830383A (fr) 1975-12-18
NL7506618A (nl) 1975-12-23
DE2526986A1 (de) 1976-01-08
IL47448A (en) 1978-04-30
IL47448A0 (en) 1975-08-31
NL184257B (nl) 1989-01-02
JPS5126212A (it) 1976-03-04
DE2526986C2 (it) 1987-11-05

Similar Documents

Publication Publication Date Title
DE68907858T2 (de) Arzneizubereitungen zur transdermalen Verabreichung von Wirkstoffen.
DE3875705T2 (de) Carbidopa-levodopa-zusammensetzung mit gesteuerter freigabe.
JP3667778B2 (ja) スフェロイド製剤
JPH057371B2 (it)
JPS62281892A (ja) エストラジオ−ル−１７β−エステル
LT3593B (en) Drugs and process for preparing thereof
EP0233849B1 (en) Composition of pregnanolole comprising a stable oil-in-water emulsion
US3070623A (en) Pharmacological compounds
US4386077A (en) Pharmaceutical composition for oral administration containing cytidine diphosphocholine
CA1042797A (en) Aqueous rafoxanide formulations
JPS62298530A (ja) 坐薬用医薬組成物
JPH0840880A (ja) 軟ゼラチンカプセル剤中のケトプロフエン溶液に基づく医薬製剤およびその調製法
JPS63406B2 (it)
US3966949A (en) Pharmaceutical compositions and preparing same
HU177873B (en) Further developped process for preparing an aequous solution containing a complex of n-/3-chloro-4-/4-chloro-phenoxy/-phenyl/-2-hydroxy-3,5-diiodo-benzamide with polyvinyl-pyrrolidone
US4150125A (en) Triglyceride ester of phosphonoacetic acid having antiviral activity
GB1600639A (en) Medicament preparation having resorption properties and method of producing the same
JPH0466847B2 (it)
US3284303A (en) Orally active progesterone compositions
JPH10226650A (ja) グリチルリチン経口投与製剤
JPS59216818A (ja) 経皮吸収外用製剤
HU179942B (en) Process for preparing injectable pharmaceutical compositions against internal parasites,particularly for the treatment and prevention of rot of sheep
JP3534793B2 (ja) グリチルリチン酸直腸製剤
Wieriks et al. Animal Reactions to, and Tolerance of, two Local Anesthetic-free Tetracycline Preparations Injected by Various Routes A Comparison of Vendarcin® with Rolitetracycline
JPH05117141A (ja) 副腎エキス含有消炎鎮痛ゲル剤