GB1472385A - Rafoxanide formulations - Google Patents

Rafoxanide formulations

Info

Publication number
GB1472385A
GB1472385A GB2582975A GB2582975A GB1472385A GB 1472385 A GB1472385 A GB 1472385A GB 2582975 A GB2582975 A GB 2582975A GB 2582975 A GB2582975 A GB 2582975A GB 1472385 A GB1472385 A GB 1472385A
Authority
GB
United Kingdom
Prior art keywords
rafoxanide
formulations
june
diiodo
salicylanilide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2582975A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1472385A publication Critical patent/GB1472385A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/609—Amides, e.g. salicylamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1472385 Salicylanilide derivative MERCK & CO Inc 17 June 1975 [19 June 1974] 25829/75 Heading C2C [Also in Division A5] 3,5 - Diiodo - 31 - chloro - 41 - (p - chlorophenoxy)salicylanilide is prepared by refluxing a mixture of 4-amino-2,4<SP>1</SP>-dichlorobiphenylether, 3,5-diiodo salicylic acid and phosphorous trichloride in chlorobenzene. Therapeutic compositions containing this compound are described (see Division A5).
GB2582975A 1974-06-19 1975-06-17 Rafoxanide formulations Expired GB1472385A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48064574A 1974-06-19 1974-06-19

Publications (1)

Publication Number Publication Date
GB1472385A true GB1472385A (en) 1977-05-04

Family

ID=23908782

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2582975A Expired GB1472385A (en) 1974-06-19 1975-06-17 Rafoxanide formulations

Country Status (10)

Country Link
JP (1) JPS5821888B2 (en)
BE (1) BE830383A (en)
CA (1) CA1042797A (en)
DE (1) DE2526986A1 (en)
FR (1) FR2275217A1 (en)
GB (1) GB1472385A (en)
IL (1) IL47448A (en)
NL (1) NL184257C (en)
PH (1) PH12304A (en)
ZA (1) ZA753921B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2247884A (en) * 1990-09-11 1992-03-18 Chanelle Chemicals Ltd Manufacture of a salicylanilide derivative
US6777448B2 (en) 2000-02-29 2004-08-17 New Pharma Research Sweden Ab Veterinary compositions for the treatment of parasitic diseases

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128632A (en) * 1978-02-13 1978-12-05 Merck & Co., Inc. Solubilization of Rafoxanide
FR2577437A1 (en) * 1985-02-21 1986-08-22 Corbiere Jerome New process for dissolving chemical compounds and aqueous preparations thus obtained

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD92776A (en) *
DE1089510B (en) * 1959-03-23 1960-09-22 Rudolf Reiss Dr Process for the preparation of aqueous, injectable solutions of 2-methoxy-4-allylphenoxyacetic acid-N, N-diaethylamide
DE1209700B (en) * 1964-05-02 1966-01-27 Boehringer & Soehne Gmbh Process for the production of a water-soluble preparation form of 3, 5-dinitro-o-toluamide
NL6816239A (en) * 1967-12-01 1969-06-03

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2247884A (en) * 1990-09-11 1992-03-18 Chanelle Chemicals Ltd Manufacture of a salicylanilide derivative
GB2247884B (en) * 1990-09-11 1994-05-11 Chanelle Chemicals Ltd Manufacture of a salicylanilide derivative
US6777448B2 (en) 2000-02-29 2004-08-17 New Pharma Research Sweden Ab Veterinary compositions for the treatment of parasitic diseases

Also Published As

Publication number Publication date
JPS5821888B2 (en) 1983-05-04
PH12304A (en) 1979-01-16
CA1042797A (en) 1978-11-21
FR2275217A1 (en) 1976-01-16
JPS5126212A (en) 1976-03-04
FR2275217B1 (en) 1979-08-17
IL47448A0 (en) 1975-08-31
BE830383A (en) 1975-12-18
NL184257C (en) 1989-06-01
NL184257B (en) 1989-01-02
IL47448A (en) 1978-04-30
ZA753921B (en) 1977-01-26
DE2526986C2 (en) 1987-11-05
AU8197375A (en) 1976-12-16
NL7506618A (en) 1975-12-23
DE2526986A1 (en) 1976-01-08

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PE20 Patent expired after termination of 20 years

Effective date: 19950616