BRPI1102284A2 - Aditivo para a nutrição animal a base de nitratos e sulfatos encapsulados para a redução da emissão de metano proveniente da fermentação ruminal - Google Patents
Aditivo para a nutrição animal a base de nitratos e sulfatos encapsulados para a redução da emissão de metano proveniente da fermentação ruminal Download PDFInfo
- Publication number
- BRPI1102284A2 BRPI1102284A2 BRPI1102284-1A2A BRPI1102284A BRPI1102284A2 BR PI1102284 A2 BRPI1102284 A2 BR PI1102284A2 BR PI1102284 A BRPI1102284 A BR PI1102284A BR PI1102284 A2 BRPI1102284 A2 BR PI1102284A2
- Authority
- BR
- Brazil
- Prior art keywords
- nitrate
- oil
- sulfate
- rumen
- calcium
- Prior art date
Links
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 title claims abstract description 100
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 title claims abstract description 91
- 150000003467 sulfuric acid derivatives Chemical class 0.000 title claims abstract description 30
- 239000000654 additive Substances 0.000 title claims description 16
- 235000019728 animal nutrition Nutrition 0.000 title claims description 14
- 230000000996 additive effect Effects 0.000 title claims description 9
- 238000000855 fermentation Methods 0.000 title abstract description 12
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- 229910002651 NO3 Inorganic materials 0.000 claims abstract description 90
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- 150000002823 nitrates Chemical class 0.000 claims abstract description 33
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims abstract description 23
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- 235000019871 vegetable fat Nutrition 0.000 claims abstract description 9
- 235000020939 nutritional additive Nutrition 0.000 claims abstract description 5
- 229910021653 sulphate ion Inorganic materials 0.000 claims abstract description 5
- 210000004767 rumen Anatomy 0.000 claims description 48
- 239000000203 mixture Substances 0.000 claims description 44
- 238000000576 coating method Methods 0.000 claims description 22
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 claims description 21
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 claims description 20
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- 235000014593 oils and fats Nutrition 0.000 description 1
- 230000021962 pH elevation Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000004466 pelleted feed Substances 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L persulfate group Chemical group S(=O)(=O)([O-])OOS(=O)(=O)[O-] JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 239000004323 potassium nitrate Substances 0.000 description 1
- 235000019252 potassium sulphite Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 235000005974 protein supplement Nutrition 0.000 description 1
- 229940116540 protein supplement Drugs 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
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- 238000005204 segregation Methods 0.000 description 1
- 235000020254 sheep milk Nutrition 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000004460 silage Substances 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 229910052979 sodium sulfide Inorganic materials 0.000 description 1
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 235000011044 succinic acid Nutrition 0.000 description 1
- 150000003444 succinic acids Chemical class 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 150000003463 sulfur Chemical class 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 150000004764 thiosulfuric acid derivatives Chemical class 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- KQBSGRWMSNFIPG-UHFFFAOYSA-N trioxane Chemical compound C1COOOC1 KQBSGRWMSNFIPG-UHFFFAOYSA-N 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- 230000004584 weight gain Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/22—Compounds of alkali metals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
- A23K50/15—Feeding-stuffs specially adapted for particular animals for ruminants containing substances which are metabolically converted to proteins, e.g. ammonium salts or urea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/20—Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
- Y02P60/22—Methane [CH4], e.g. from rice paddies
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Inorganic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Medicinal Preparation (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI1102284-1A2A BRPI1102284A2 (pt) | 2011-05-23 | 2011-05-23 | Aditivo para a nutrição animal a base de nitratos e sulfatos encapsulados para a redução da emissão de metano proveniente da fermentação ruminal |
| MX2013012715A MX2013012715A (es) | 2011-05-23 | 2012-05-23 | Aditivo para alimentacion animal basado en nitratos y sulfatos encapsulados para reducir la emision de metano derivada de la fermentacion ruminal. |
| ARP120101819A AR086529A1 (es) | 2011-05-23 | 2012-05-23 | Aditivos nutricionales y suplementos de forma granular para rumiantes que contienen nitratos y sulfatos encapsulados para reducir las emisiones de metano derivadas de la fermentacion ruminal |
| US14/119,245 US20140099406A1 (en) | 2011-05-23 | 2012-05-23 | Feed additive based on encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| CA2832671A CA2832671A1 (en) | 2011-05-23 | 2012-05-23 | Use of encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| PCT/BR2012/000157 WO2012159186A1 (en) | 2011-05-23 | 2012-05-23 | Use of encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| UY0001034091A UY34091A (es) | 2011-05-23 | 2012-05-23 | Uso de nitratos y sulfatos encapsulados para reducir la emisión de metano que se deriva de la fermentación ruminal |
| RU2013147092/13A RU2013147092A (ru) | 2011-05-23 | 2012-05-23 | Применение инкапсулированных нитратов и сульфатов для снижения выделения метана, образующегося при ферментативных процессах в рубце жвачных |
| KR1020137032583A KR20140033097A (ko) | 2011-05-23 | 2012-05-23 | 반추위 발효로부터 유도된 메탄 방출을 감소시키기 위한 캅셀화 질산염 및 황산염의 용도 |
| JP2014511689A JP2014515265A (ja) | 2011-05-23 | 2012-05-23 | 第一胃内発酵由来のメタン放出を低減するカプセル化硝酸塩及び硫酸塩の使用 |
| EP12726726.8A EP2713768A1 (en) | 2011-05-23 | 2012-05-23 | Use of encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| AU2012260375A AU2012260375A1 (en) | 2011-05-23 | 2012-05-23 | Use of encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| CN201280025128.2A CN103547168A (zh) | 2011-05-23 | 2012-05-23 | 包封的硝酸盐和硫酸盐在减少由瘤胃发酵产生的甲烷排放中的用途 |
| ZA2013/08009A ZA201308009B (en) | 2011-05-23 | 2013-10-29 | Use of encapsulated nitrates and sulfates to reduce methane emission derived from ruminal fermentation |
| US15/043,249 US20160165928A1 (en) | 2011-05-23 | 2016-02-12 | Methods of reducing methane emission derived from ruminal fermentation while simultaneously reducing risk of nitrate intoxication |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI1102284-1A2A BRPI1102284A2 (pt) | 2011-05-23 | 2011-05-23 | Aditivo para a nutrição animal a base de nitratos e sulfatos encapsulados para a redução da emissão de metano proveniente da fermentação ruminal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1102284A2 true BRPI1102284A2 (pt) | 2013-11-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1102284-1A2A BRPI1102284A2 (pt) | 2011-05-23 | 2011-05-23 | Aditivo para a nutrição animal a base de nitratos e sulfatos encapsulados para a redução da emissão de metano proveniente da fermentação ruminal |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20140099406A1 (enExample) |
| EP (1) | EP2713768A1 (enExample) |
| JP (1) | JP2014515265A (enExample) |
| KR (1) | KR20140033097A (enExample) |
| CN (1) | CN103547168A (enExample) |
| AR (1) | AR086529A1 (enExample) |
| AU (1) | AU2012260375A1 (enExample) |
| BR (1) | BRPI1102284A2 (enExample) |
| CA (1) | CA2832671A1 (enExample) |
| MX (1) | MX2013012715A (enExample) |
| RU (1) | RU2013147092A (enExample) |
| UY (1) | UY34091A (enExample) |
| WO (1) | WO2012159186A1 (enExample) |
| ZA (1) | ZA201308009B (enExample) |
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| CN103070324B (zh) * | 2013-01-22 | 2015-03-04 | 喀什昌鼎工贸有限责任公司 | 脱毒剂及使用脱毒剂防止棉粕酸败的方法 |
| US11951138B2 (en) | 2013-03-14 | 2024-04-09 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) | Microbial compositions comprising rumen microflora and uses thereof |
| KR101641755B1 (ko) * | 2013-12-09 | 2016-07-21 | 순천대학교 산학협력단 | 반추위 내 메탄 저감 및 발효 개선을 위한 미생물 및 이의 이용 |
| CN103766657B (zh) * | 2014-01-23 | 2015-06-17 | 浙江大学 | 一种减少猪甲烷排放的饲料添加剂 |
| CN103798523A (zh) * | 2014-03-10 | 2014-05-21 | 南昌资环生态科技有限公司 | 一种同源性瘤胃微生态调控剂的制备方法及应用 |
| KR101447414B1 (ko) * | 2014-05-14 | 2014-10-06 | (주)영수 | 사료 조성물 및 그 제조방법 |
| CN104186958B (zh) * | 2014-05-23 | 2017-11-21 | 广州英赛特生物技术有限公司 | 肉豆蔻酸铜作为饲料添加剂的应用 |
| RU2755947C2 (ru) * | 2014-12-05 | 2021-09-23 | Кэн Текнолоджиз, Инк. | Добавка к корму для животных и способ |
| JP6547148B2 (ja) * | 2015-01-21 | 2019-07-24 | 静岡県 | 野生の反芻動物駆除用組成物及び野生の反芻動物の駆除方法 |
| CN104605162A (zh) * | 2015-01-26 | 2015-05-13 | 河南农业大学 | 米曲霉作为肉牛肠道及粪便甲烷抑制剂的应用 |
| KR102273231B1 (ko) * | 2015-01-30 | 2021-07-05 | 이데미쓰 고산 가부시키가이샤 | 기능성 사료 |
| KR101588163B1 (ko) * | 2015-04-14 | 2016-01-22 | 김남형 | 가축 사료의 외관개선 및 사료 이용 효율 향상을 위한 펠렛코팅 오일복합제 및 이의 사료 코팅 용도 |
| CN105016920A (zh) * | 2015-07-08 | 2015-11-04 | 湖北昊旻生物科技有限公司 | 一种全水溶化肥养分控失剂及其制备方法 |
| US11957139B2 (en) | 2016-01-19 | 2024-04-16 | Evonik Operations Gmbh | Compositions for improving nitrogen utilization in a ruminant |
| WO2017187433A1 (en) | 2016-04-26 | 2017-11-02 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) | Regulation of feed efficiency and methane production in ruminating animals |
| CN106173339A (zh) * | 2016-07-20 | 2016-12-07 | 南京农业大学 | 三硝酸甘油酯的应用 |
| CN106165771A (zh) * | 2016-07-20 | 2016-11-30 | 南京农业大学 | 2,2双甲基‑3‑(硝基氧基)丙酸的应用 |
| KR101911465B1 (ko) | 2016-11-25 | 2018-10-24 | 전북대학교 산학협력단 | 반추동물의 반추위 내 메탄가스 저감을 위한 질산염 코팅 조성물 및 이의 제조방법 |
| AU2018226085B2 (en) * | 2017-02-21 | 2023-07-20 | Dsm Ip Assets B.V. | Use of a feed composition for reducing methane emission in rumi-nants, and/or to improve ruminant performance |
| DK3641777T3 (da) * | 2017-06-23 | 2026-04-13 | Can Tech Inc | Fremgangsmåde til forbedring af kødkvalitet |
| CN107788236A (zh) * | 2017-11-08 | 2018-03-13 | 中国科学院亚热带农业生态研究所 | 一种提高稻草饲用价值和降低反刍家畜甲烷排放的方法 |
| KR102039500B1 (ko) * | 2018-03-09 | 2019-11-01 | 환경화학 주식회사 | 이온 유기태화 미네랄을 제조하는 방법 |
| CN108419916A (zh) * | 2018-04-08 | 2018-08-21 | 俞小峰 | 一种复合包覆酸化剂的制备方法 |
| US20220030914A1 (en) * | 2018-12-07 | 2022-02-03 | Cj Cheiljedang Corporation | Granular feed additive |
| BR112021020454A2 (pt) * | 2019-04-12 | 2021-12-14 | Locus Ip Co Llc | Tratamentos de pastagem para sequestro de carbono e redução de emissões de gases de efeito estufa produzidas pela pecuária melhorados |
| CN110511575B (zh) * | 2019-07-26 | 2021-09-14 | 广西大学 | 一种环保抗菌型纳米纤维素复合大豆油基聚合物泡沫的制备方法 |
| CN110420972A (zh) * | 2019-08-06 | 2019-11-08 | 德州正朔环保有限公司 | 固体废弃物生物降解酵素 |
| CN111103423B (zh) * | 2019-12-31 | 2021-11-05 | 无锡市尚沃医疗电子股份有限公司 | 一种检测肠道菌群代谢气体的呼气试验方法 |
| JP2023533224A (ja) * | 2020-06-30 | 2023-08-02 | ローカス ソリューションズ アイピーシーオー，エルエルシー | 家畜の健康及びメタン削減のための改善された飼料ブロックサプリメント |
| WO2023133067A1 (en) * | 2022-01-04 | 2023-07-13 | Castillo Alejandro R | Livestock feed additives to mitigate the environmental impact of ruminants |
| CN118541033A (zh) * | 2022-01-18 | 2024-08-23 | 伊士曼化工公司 | 纤维素聚合物包被的颗粒 |
| CN118678962A (zh) | 2022-02-02 | 2024-09-20 | 集富营养有限公司 | 用于改善反刍动物的肠道健康和/或奶生产的组合物、其用途和方法 |
| CN114716671B (zh) * | 2022-04-22 | 2022-11-04 | 深圳飞扬骏研新材料股份有限公司 | 耐盐雾聚天门冬氨酸酯的制备方法、耐盐雾聚天门冬氨酸酯及涂料 |
| US12084610B2 (en) * | 2022-07-01 | 2024-09-10 | Arkea Bio Corp. | Compositions and methods for reducing deleterious atmospheric gas emissions from flooded ecosystems |
| GB202210434D0 (en) * | 2022-07-15 | 2022-08-31 | Carus Animal Health Ltd | Agricultural compositions and methods |
| US12582142B1 (en) * | 2022-08-08 | 2026-03-24 | Alga Biosciences Inc. | Feed supplements for reducing enteric methane emissions and methods thereof |
| CN119968125A (zh) * | 2022-10-03 | 2025-05-09 | 日本史迪士生物科学株式会社 | 反刍动物的甲烷产生抑制剂 |
| JPWO2024111392A1 (enExample) * | 2022-11-21 | 2024-05-30 | ||
| CN116570584B (zh) * | 2023-05-08 | 2025-02-18 | 广州白云山医药集团股份有限公司白云山制药总厂 | 盐霉素在制备降尿酸和/或治疗高尿酸血症的药物中的应用 |
| AU2024327436A1 (en) | 2023-08-24 | 2026-03-05 | Synergraze Inc. | Methods and compositions for improving feed-efficiency in animals and reducing enteric methane emissions |
| US12448600B2 (en) | 2023-08-24 | 2025-10-21 | Synergraze Inc. | Extraction of antimethanogenic compounds |
| KR102909259B1 (ko) * | 2024-09-28 | 2026-01-08 | (주) 칼리시 | 표적 물질 조절 제제 제조 방법 및 장치 |
| CN119867217A (zh) * | 2025-01-17 | 2025-04-25 | 山东东粮农业科技有限公司 | 用于缓解反刍动物瘤胃酸中毒的饲料添加剂及其生产工艺 |
Family Cites Families (27)
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|---|---|---|---|---|
| US1475492A (en) * | 1921-06-28 | 1923-11-27 | Herbert J Krase | Hydrated calcium nitrate and method of making same |
| GB359163A (en) * | 1930-09-26 | 1931-10-22 | Ig Farbenindustrie Ag | Improvements in the storage of fertilisers which are hygroscopic or have a tendency to cake |
| US3119738A (en) * | 1962-04-12 | 1964-01-28 | Wisconsin Alumni Res Found | Medication for ruminants |
| GB1445560A (en) | 1972-09-14 | 1976-08-11 | Ici Ltd | Animal feeds and additives therefor |
| AU650113B2 (en) | 1991-04-05 | 1994-06-09 | Eli Lilly And Company | Sustained release capsule and formulations |
| BR9506533A (pt) * | 1994-01-20 | 1997-09-16 | Pastoral Agric Res Inst Nz Ltd | Dispositivo para administração de materiais benéficos a ruminantes |
| JP3232193B2 (ja) * | 1994-06-02 | 2001-11-26 | 潤一 高橋 | 反すう動物給与用組成物及び反すう動物の飼料効率向上方法 |
| NO300037B1 (no) * | 1994-06-24 | 1997-03-24 | Norsk Hydro As | Gjödselprodukt og kondisjoneringsmiddel for reduksjon av hygroskopisitet og stövdannelse til gjödsel |
| GB2320410A (en) * | 1996-12-20 | 1998-06-24 | Rowett Research Services | Animal feed containing a lignin-urea product |
| DE19920816A1 (de) * | 1999-05-05 | 2000-11-09 | Aventis Pharma Gmbh | Cephaibole, neue Antiparasitika aus Acremonium tubakii, Verfahren zu ihrer Herstellung und Verwendung derselben |
| WO2001000921A1 (en) | 1999-06-28 | 2001-01-04 | Betflex Inc. | Multilayer cementitious structure |
| US6231895B1 (en) | 2000-03-01 | 2001-05-15 | Agway, Inc | Feedstock for ruminants with controlled-release non-protein nitrogen |
| US7666399B2 (en) * | 2004-12-13 | 2010-02-23 | The Andersons, Inc. | Pesticidal fertilizer |
| JP5192108B2 (ja) | 2001-09-19 | 2013-05-08 | 株式会社ヤクルト本社 | 反芻動物用のメタン生成抑制用組成物及び飼料用組成物 |
| AU2003215232A1 (en) | 2002-02-12 | 2003-09-04 | Alltech, Inc. | Amylase feed supplements for improved ruminant nutrition |
| US6620453B1 (en) * | 2002-04-24 | 2003-09-16 | Agri-Nutrients Technology Group, Inc. | Controlled release NPN ruminant feed composition |
| US7105191B2 (en) * | 2003-05-23 | 2006-09-12 | Tetra Technologies, Inc. | Calcium supplement for animals and method for making same |
| BR0305047B1 (pt) | 2003-08-01 | 2014-07-08 | Marcelo Almeida Conceicao | Composto alimientar para animais e seu processo de fabricação |
| WO2006040537A1 (en) * | 2004-10-12 | 2006-04-20 | Rowett Research Institute | Improved ruminant feeding |
| US8182851B2 (en) * | 2006-06-23 | 2012-05-22 | Church & Dwight Co., Inc. | Ruminant feedstock dietary supplement |
| EP2035351B1 (en) * | 2006-06-30 | 2017-06-28 | Stamicarbon B.V. | Coated fertilizer |
| US9578891B2 (en) * | 2006-08-07 | 2017-02-28 | Novozymes A/S | Enzyme granules for animal feed |
| US8827542B2 (en) * | 2008-07-28 | 2014-09-09 | Ganado Technologies Corp. | Apparatus and method to feed livestock |
| US7966971B2 (en) | 2008-05-23 | 2011-06-28 | C-Lock Inc. | Method and system for monitoring and reducing ruminant methane production |
| WO2010071222A1 (ja) | 2008-12-20 | 2010-06-24 | 味の素株式会社 | 反芻動物用メタン生成抑制剤および飼料組成物 |
| UY32802A (es) * | 2009-07-23 | 2011-01-31 | Provimi Holding B V | Composiciones para reducir la metanogénesis gastrointestinal en rumiantes |
| KR20120051725A (ko) * | 2009-07-30 | 2012-05-22 | 이데미쓰 고산 가부시키가이샤 | 코트 제제 |
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2011
- 2011-05-23 BR BRPI1102284-1A2A patent/BRPI1102284A2/pt not_active Application Discontinuation
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2012
- 2012-05-23 CN CN201280025128.2A patent/CN103547168A/zh active Pending
- 2012-05-23 AR ARP120101819A patent/AR086529A1/es unknown
- 2012-05-23 MX MX2013012715A patent/MX2013012715A/es not_active Application Discontinuation
- 2012-05-23 KR KR1020137032583A patent/KR20140033097A/ko not_active Withdrawn
- 2012-05-23 JP JP2014511689A patent/JP2014515265A/ja active Pending
- 2012-05-23 WO PCT/BR2012/000157 patent/WO2012159186A1/en not_active Ceased
- 2012-05-23 UY UY0001034091A patent/UY34091A/es not_active Application Discontinuation
- 2012-05-23 US US14/119,245 patent/US20140099406A1/en not_active Abandoned
- 2012-05-23 AU AU2012260375A patent/AU2012260375A1/en not_active Abandoned
- 2012-05-23 RU RU2013147092/13A patent/RU2013147092A/ru not_active Application Discontinuation
- 2012-05-23 EP EP12726726.8A patent/EP2713768A1/en not_active Withdrawn
- 2012-05-23 CA CA2832671A patent/CA2832671A1/en not_active Abandoned
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2013
- 2013-10-29 ZA ZA2013/08009A patent/ZA201308009B/en unknown
-
2016
- 2016-02-12 US US15/043,249 patent/US20160165928A1/en not_active Abandoned
Also Published As
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|---|---|
| MX2013012715A (es) | 2014-05-28 |
| US20160165928A1 (en) | 2016-06-16 |
| KR20140033097A (ko) | 2014-03-17 |
| RU2013147092A (ru) | 2015-06-27 |
| ZA201308009B (en) | 2014-08-27 |
| UY34091A (es) | 2013-01-03 |
| AU2012260375A1 (en) | 2013-10-31 |
| EP2713768A1 (en) | 2014-04-09 |
| WO2012159186A1 (en) | 2012-11-29 |
| AR086529A1 (es) | 2013-12-18 |
| CN103547168A (zh) | 2014-01-29 |
| JP2014515265A (ja) | 2014-06-30 |
| CA2832671A1 (en) | 2012-11-29 |
| US20140099406A1 (en) | 2014-04-10 |
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