BRPI1013394B1 - Composto inibidor da replicação do vírus da hepatite c, sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, usos do composto e do sal farmaceuticamente aceitável do mesmo - Google Patents

Composto inibidor da replicação do vírus da hepatite c, sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, usos do composto e do sal farmaceuticamente aceitável do mesmo Download PDF

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Publication number
BRPI1013394B1
BRPI1013394B1 BRPI1013394-1A BRPI1013394A BRPI1013394B1 BR PI1013394 B1 BRPI1013394 B1 BR PI1013394B1 BR PI1013394 A BRPI1013394 A BR PI1013394A BR PI1013394 B1 BRPI1013394 B1 BR PI1013394B1
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Brazil
Prior art keywords
mmol
group
mixture
compound
hcv
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BRPI1013394-1A
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English (en)
Portuguese (pt)
Inventor
Craig A. Coburn
John A. Mccauley
Joseph P. Vacca
Hao Wu
Bin Hu
Richard Soll
Fei Sun
Xinghai Wang
Man Yan
Chengren Zhang
Mingwei Zheng
Bin Zhong
Jian Zhu
Steven W. Ludmerer
Kun Liu
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Merck Sharp & Dohme Corp
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Application filed by Merck Sharp & Dohme Corp filed Critical Merck Sharp & Dohme Corp
Publication of BRPI1013394A2 publication Critical patent/BRPI1013394A2/pt
Publication of BRPI1013394B1 publication Critical patent/BRPI1013394B1/pt

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    • C07D498/04—Ortho-condensed systems
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    • C07—ORGANIC CHEMISTRY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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BRPI1013394-1A 2009-03-27 2010-03-25 Composto inibidor da replicação do vírus da hepatite c, sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, usos do composto e do sal farmaceuticamente aceitável do mesmo BRPI1013394B1 (pt)

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