BRPI0923161B1 - dispositivo implantável de uma peça contendo rilpivirina - Google Patents

dispositivo implantável de uma peça contendo rilpivirina Download PDF

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Publication number
BRPI0923161B1
BRPI0923161B1 BRPI0923161A BRPI0923161A BRPI0923161B1 BR PI0923161 B1 BRPI0923161 B1 BR PI0923161B1 BR PI0923161 A BRPI0923161 A BR PI0923161A BR PI0923161 A BRPI0923161 A BR PI0923161A BR PI0923161 B1 BRPI0923161 B1 BR PI0923161B1
Authority
BR
Brazil
Prior art keywords
tmc278
weight
implantable device
samples
dmso
Prior art date
Application number
BRPI0923161A
Other languages
English (en)
Portuguese (pt)
Inventor
M Schachter Deborah
Cui Han
Elvire Colette Baert Lieven
Zhang Qiang
Original Assignee
Janssen R&D Ireland
Janssen Sciences Ireland Uc
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen R&D Ireland, Janssen Sciences Ireland Uc, Tibotec Pharm Ltd filed Critical Janssen R&D Ireland
Publication of BRPI0923161A2 publication Critical patent/BRPI0923161A2/pt
Publication of BRPI0923161B1 publication Critical patent/BRPI0923161B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
BRPI0923161A 2008-12-24 2009-12-24 dispositivo implantável de uma peça contendo rilpivirina BRPI0923161B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14069408P 2008-12-24 2008-12-24
PCT/EP2009/067933 WO2010072844A1 (en) 2008-12-24 2009-12-24 Implantable devices for treating hiv

Publications (2)

Publication Number Publication Date
BRPI0923161A2 BRPI0923161A2 (pt) 2016-02-10
BRPI0923161B1 true BRPI0923161B1 (pt) 2019-01-15

Family

ID=42167643

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923161A BRPI0923161B1 (pt) 2008-12-24 2009-12-24 dispositivo implantável de uma peça contendo rilpivirina

Country Status (18)

Country Link
US (3) US20110256206A1 (de)
EP (1) EP2381961B1 (de)
JP (1) JP5612602B2 (de)
KR (1) KR101726615B1 (de)
CN (1) CN102711834B (de)
AU (1) AU2009332910B2 (de)
BR (1) BRPI0923161B1 (de)
CA (1) CA2747955C (de)
ES (1) ES2607107T3 (de)
HK (1) HK1172842A1 (de)
IL (1) IL213542A (de)
MX (1) MX2011006856A (de)
MY (1) MY160360A (de)
NZ (1) NZ593950A (de)
RU (1) RU2546529C2 (de)
SG (2) SG196774A1 (de)
WO (1) WO2010072844A1 (de)
ZA (1) ZA201104669B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2515877B1 (de) 2009-12-21 2016-08-10 Janssen Sciences Ireland UC Abbaubares entfernbares implantat zur verzögerten freisetzung eines wirkstoffes
US9423528B2 (en) 2012-06-25 2016-08-23 Johnson & Johnson Vision Care, Inc. Method of making silicone containing contact lens with reduced amount of diluents
US20130341811A1 (en) * 2012-06-25 2013-12-26 Johnson & Johnson Vision Care, Inc. Lens comprising low and high molecular weight polyamides
SG11201804037XA (en) * 2015-11-16 2018-06-28 Evonik Roehm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
RU2755130C2 (ru) * 2016-05-12 2021-09-13 Мерк Шарп И Доум Корп. Система доставки лекарств для доставки противовирусных средств

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743446B2 (en) * 1999-12-15 2004-06-01 The Ohio State University Research Foundation Methods for stabilizing biologically active agents encapsulated in biodegradable controlled-release polymers
JP2003525613A (ja) * 2000-03-03 2003-09-02 バレンティス，インコーポレイティド 核酸送達用の改良ポロキサマーおよびポロキサミン組成物
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
US7201925B2 (en) * 2002-04-23 2007-04-10 Nueryst Pharmaceuticals Corp. Treatment of ungual and subungual diseases
KR20040111466A (ko) 2002-05-03 2004-12-31 얀센 파마슈티카 엔.브이. 폴리머성 마이크로에멀젼
AU2004313245B2 (en) * 2003-12-30 2011-04-14 Durect Corporation Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents, preferably a GNRH
SI1824460T1 (sl) * 2004-11-10 2015-04-30 Tolmar Therapeutics, Inc. Stabiliziran polimerni dostavni sistem
TWI457136B (zh) * 2005-04-04 2014-10-21 Tibotec Pharm Ltd Ｈｉｖ-感染之預防
EP1893180A2 (de) * 2005-06-07 2008-03-05 Pfizer Products Inc. Multipartikeln mit schwer löslichen arzneimitteln und eine schnelle arzneimittelfreisetzung ergebende träger
ES2414982T7 (es) * 2006-01-20 2021-11-05 Janssen Sciences Ireland Unlimited Co Tratamiento a largo plazo de infección por VIH con TCM278
BRPI0713334B1 (pt) * 2006-06-23 2024-02-20 Janssen Sciences Ireland Uc Uso de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]-amino]-2-pirimidinil]-amino]-benzonitrila para tratar ou prevenir infecção por HIV

Also Published As

Publication number Publication date
ZA201104669B (en) 2018-11-28
JP5612602B2 (ja) 2014-10-22
KR101726615B1 (ko) 2017-04-13
IL213542A0 (en) 2011-07-31
RU2011130557A (ru) 2013-01-27
US20220079875A1 (en) 2022-03-17
WO2010072844A1 (en) 2010-07-01
AU2009332910A1 (en) 2011-07-07
CN102711834A (zh) 2012-10-03
CA2747955A1 (en) 2010-07-01
RU2546529C2 (ru) 2015-04-10
BRPI0923161A2 (pt) 2016-02-10
SG196774A1 (en) 2014-02-13
EP2381961A1 (de) 2011-11-02
NZ593950A (en) 2013-08-30
MX2011006856A (es) 2011-08-03
HK1172842A1 (zh) 2013-05-03
SG172398A1 (en) 2011-07-28
KR20110117100A (ko) 2011-10-26
US20110256206A1 (en) 2011-10-20
AU2009332910B2 (en) 2015-10-15
IL213542A (en) 2017-02-28
JP2012513969A (ja) 2012-06-21
ES2607107T3 (es) 2017-03-29
CN102711834B (zh) 2015-08-26
EP2381961B1 (de) 2016-09-14
US20180235872A1 (en) 2018-08-23
MY160360A (en) 2017-02-28
CA2747955C (en) 2017-06-13

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: JANSSEN RANDD IRELAND (IE)

B25A Requested transfer of rights approved

Owner name: JANSSEN SCIENCES IRELAND UC (IE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/12/2009, OBSERVADAS AS CONDICOES LEGAIS.