JP5612602B2 - Hiv処置用の移植可能デバイス - Google Patents

Hiv処置用の移植可能デバイス Download PDF

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JP5612602B2
JP5612602B2 JP2011542837A JP2011542837A JP5612602B2 JP 5612602 B2 JP5612602 B2 JP 5612602B2 JP 2011542837 A JP2011542837 A JP 2011542837A JP 2011542837 A JP2011542837 A JP 2011542837A JP 5612602 B2 JP5612602 B2 JP 5612602B2
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tmc278
total weight
dmso
release
samples
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Japanese (ja)
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JP2012513969A (ja
Inventor
シヤクター,デボラ・エム
ツアン,チヤン
バールト,リーベン・エルビール・コレツト
クイ,ハン
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ヤンセン・アールアンドデイ・アイルランド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
JP2011542837A 2008-12-24 2009-12-24 Hiv処置用の移植可能デバイス Active JP5612602B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14069408P 2008-12-24 2008-12-24
US61/140,694 2008-12-24
PCT/EP2009/067933 WO2010072844A1 (en) 2008-12-24 2009-12-24 Implantable devices for treating hiv

Publications (2)

Publication Number Publication Date
JP2012513969A JP2012513969A (ja) 2012-06-21
JP5612602B2 true JP5612602B2 (ja) 2014-10-22

Family

ID=42167643

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011542837A Active JP5612602B2 (ja) 2008-12-24 2009-12-24 Hiv処置用の移植可能デバイス

Country Status (18)

Country Link
US (3) US20110256206A1 (de)
EP (1) EP2381961B1 (de)
JP (1) JP5612602B2 (de)
KR (1) KR101726615B1 (de)
CN (1) CN102711834B (de)
AU (1) AU2009332910B2 (de)
BR (1) BRPI0923161B1 (de)
CA (1) CA2747955C (de)
ES (1) ES2607107T3 (de)
HK (1) HK1172842A1 (de)
IL (1) IL213542A (de)
MX (1) MX2011006856A (de)
MY (1) MY160360A (de)
NZ (1) NZ593950A (de)
RU (1) RU2546529C2 (de)
SG (2) SG196774A1 (de)
WO (1) WO2010072844A1 (de)
ZA (1) ZA201104669B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2515877B1 (de) 2009-12-21 2016-08-10 Janssen Sciences Ireland UC Abbaubares entfernbares implantat zur verzögerten freisetzung eines wirkstoffes
US9423528B2 (en) 2012-06-25 2016-08-23 Johnson & Johnson Vision Care, Inc. Method of making silicone containing contact lens with reduced amount of diluents
US20130341811A1 (en) * 2012-06-25 2013-12-26 Johnson & Johnson Vision Care, Inc. Lens comprising low and high molecular weight polyamides
SG11201804037XA (en) * 2015-11-16 2018-06-28 Evonik Roehm Gmbh Injection solution comprising a non-nucleoside reverse-transcriptase inhibitor and poly(lactide-co-glycolide)
RU2755130C2 (ru) * 2016-05-12 2021-09-13 Мерк Шарп И Доум Корп. Система доставки лекарств для доставки противовирусных средств

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743446B2 (en) * 1999-12-15 2004-06-01 The Ohio State University Research Foundation Methods for stabilizing biologically active agents encapsulated in biodegradable controlled-release polymers
JP2003525613A (ja) * 2000-03-03 2003-09-02 バレンティス,インコーポレイティド 核酸送達用の改良ポロキサマーおよびポロキサミン組成物
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
US7201925B2 (en) * 2002-04-23 2007-04-10 Nueryst Pharmaceuticals Corp. Treatment of ungual and subungual diseases
KR20040111466A (ko) 2002-05-03 2004-12-31 얀센 파마슈티카 엔.브이. 폴리머성 마이크로에멀젼
AU2004313245B2 (en) * 2003-12-30 2011-04-14 Durect Corporation Polymeric implants, preferably containing a mixture of PEG and PLG, for controlled release of active agents, preferably a GNRH
SI1824460T1 (sl) * 2004-11-10 2015-04-30 Tolmar Therapeutics, Inc. Stabiliziran polimerni dostavni sistem
TWI457136B (zh) * 2005-04-04 2014-10-21 Tibotec Pharm Ltd Hiv-感染之預防
EP1893180A2 (de) * 2005-06-07 2008-03-05 Pfizer Products Inc. Multipartikeln mit schwer löslichen arzneimitteln und eine schnelle arzneimittelfreisetzung ergebende träger
ES2414982T7 (es) * 2006-01-20 2021-11-05 Janssen Sciences Ireland Unlimited Co Tratamiento a largo plazo de infección por VIH con TCM278
BRPI0713334B1 (pt) * 2006-06-23 2024-02-20 Janssen Sciences Ireland Uc Uso de 4-[[4-[[4-(2-cianoetenil)-2,6-dimetilfenil]-amino]-2-pirimidinil]-amino]-benzonitrila para tratar ou prevenir infecção por HIV

Also Published As

Publication number Publication date
ZA201104669B (en) 2018-11-28
KR101726615B1 (ko) 2017-04-13
IL213542A0 (en) 2011-07-31
RU2011130557A (ru) 2013-01-27
US20220079875A1 (en) 2022-03-17
WO2010072844A1 (en) 2010-07-01
AU2009332910A1 (en) 2011-07-07
CN102711834A (zh) 2012-10-03
CA2747955A1 (en) 2010-07-01
RU2546529C2 (ru) 2015-04-10
BRPI0923161A2 (pt) 2016-02-10
SG196774A1 (en) 2014-02-13
EP2381961A1 (de) 2011-11-02
NZ593950A (en) 2013-08-30
MX2011006856A (es) 2011-08-03
HK1172842A1 (zh) 2013-05-03
SG172398A1 (en) 2011-07-28
KR20110117100A (ko) 2011-10-26
US20110256206A1 (en) 2011-10-20
AU2009332910B2 (en) 2015-10-15
BRPI0923161B1 (pt) 2019-01-15
IL213542A (en) 2017-02-28
JP2012513969A (ja) 2012-06-21
ES2607107T3 (es) 2017-03-29
CN102711834B (zh) 2015-08-26
EP2381961B1 (de) 2016-09-14
US20180235872A1 (en) 2018-08-23
MY160360A (en) 2017-02-28
CA2747955C (en) 2017-06-13

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