BRPI0918134A2 - derivado de prostaglandina i2 - Google Patents

derivado de prostaglandina i2

Info

Publication number
BRPI0918134A2
BRPI0918134A2 BRPI0918134A BRPI0918134A BRPI0918134A2 BR PI0918134 A2 BRPI0918134 A2 BR PI0918134A2 BR PI0918134 A BRPI0918134 A BR PI0918134A BR PI0918134 A BRPI0918134 A BR PI0918134A BR PI0918134 A2 BRPI0918134 A2 BR PI0918134A2
Authority
BR
Brazil
Prior art keywords
prostaglandin
derivative
Prior art date
Application number
BRPI0918134A
Other languages
English (en)
Inventor
Katsuhiko Konishi
Masahiro Amakawa
Shin Teradaira
Takahiko Murata
Yasushi Matsumura
Original Assignee
Asahi Glass Co Ltd
Kaken Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd, Kaken Pharma Co Ltd filed Critical Asahi Glass Co Ltd
Publication of BRPI0918134A2 publication Critical patent/BRPI0918134A2/pt
Publication of BRPI0918134B1 publication Critical patent/BRPI0918134B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0918134-2A 2008-09-10 2009-09-08 Derivado de prostaglandina i2 BRPI0918134B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2008232133 2008-09-10
JP2008-232133 2008-09-10
JP2009168193 2009-07-16
JP2009-168193 2009-07-16
PCT/JP2009/065690 WO2010029925A1 (ja) 2008-09-10 2009-09-08 新規なプロスタグランジンi2誘導体

Publications (2)

Publication Number Publication Date
BRPI0918134A2 true BRPI0918134A2 (pt) 2016-03-01
BRPI0918134B1 BRPI0918134B1 (pt) 2019-02-12

Family

ID=42005178

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918134-2A BRPI0918134B1 (pt) 2008-09-10 2009-09-08 Derivado de prostaglandina i2

Country Status (15)

Country Link
US (4) US8394844B2 (pt)
EP (1) EP2343292B1 (pt)
JP (1) JP5468007B2 (pt)
KR (1) KR101645752B1 (pt)
CN (1) CN102209719B (pt)
AU (1) AU2009292555B2 (pt)
BR (1) BRPI0918134B1 (pt)
CA (1) CA2736039C (pt)
DK (1) DK2343292T3 (pt)
ES (1) ES2522971T3 (pt)
MX (1) MX2011002573A (pt)
PL (1) PL2343292T3 (pt)
PT (1) PT2343292E (pt)
RU (1) RU2509768C2 (pt)
WO (1) WO2010029925A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2343292B1 (en) 2008-09-10 2014-08-06 Asahi Glass Company, Limited Novel prostaglandin i2 derivative
US8791122B2 (en) 2009-06-26 2014-07-29 Nippon Shinyaku Co., Ltd. Form-I crystal of 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide and method for producing the same
AU2011225259B2 (en) * 2010-03-08 2015-07-23 AGC Inc. Novel EP4 agonist
ES2637286T3 (es) 2011-07-08 2017-10-11 Defensin Therapeutics Aps Tratamiento oral de la enfermedad inflamatoria intestinal
WO2014065382A1 (ja) * 2012-10-26 2014-05-01 旭硝子株式会社 ジフルオロエステル化合物の製造方法
JP6694385B2 (ja) 2013-08-09 2020-05-13 アーデリクス,インコーポレーテッド リン酸塩輸送阻害のための化合物及び方法
WO2016168090A1 (en) * 2015-04-14 2016-10-20 Nueon, Inc. Method and apparatus for determining markers of health by analysis of blood
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス, インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ
CN114341098B (zh) * 2019-10-11 2024-03-12 国立大学法人东北大学 环戊烷化合物的制备方法、内酯化合物的制备方法、二醇化合物的制备方法和化合物
HU231350B1 (hu) * 2019-12-18 2023-01-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt Eljárás királis prosztaglandin-enol intermedier előállítására, és az eljárásban hasznos köztitermék vegyületek

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788209A (fr) 1971-09-01 1973-02-28 Pfizer Derives tetrazoyliques des prostaglandines naturelles
DE2405255A1 (de) 1973-02-08 1974-08-15 Sandoz Ag Neue tetrazolderivate und verfahren zu ihrer herstellung
US4705806A (en) * 1978-02-13 1987-11-10 Morton Jr Douglas R Prostacyclin analogs
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
JPH0655730B2 (ja) 1987-07-17 1994-07-27 ザ ヌトラスウィート カンパニー 強力甘味剤
KR900701177A (ko) * 1988-07-12 1990-12-01 원본미기재 고농도 감미제
US4881288A (en) * 1988-07-13 1989-11-21 Tennant Trend Inc. Center feed dispenser for cleaning solution
JP2500371B2 (ja) 1993-11-08 1996-05-29 工業技術院長 半導体薄膜の成長方法
JP3719524B2 (ja) 1994-03-17 2005-11-24 旭硝子株式会社 ジハロゲン化プロスタサイクリン類の製造方法
ES2116630T3 (es) * 1994-02-17 1998-07-16 Asahi Glass Co Ltd Difluorprostaciclinas; productos intermediarios y procedimientos para su preparacion.
JP3769738B2 (ja) 1994-04-11 2006-04-26 旭硝子株式会社 ジフルオロプロスタサイクリン類
JPH08217772A (ja) 1995-02-13 1996-08-27 Asahi Glass Co Ltd ジフルオロ置換ビニルエーテル類の製造方法
TW401408B (en) * 1995-07-21 2000-08-11 Fujisawa Pharmaceutical Co Heterocyclic compounds having prostaglandin I2 agonism
JP3598611B2 (ja) 1995-10-17 2004-12-08 旭硝子株式会社 ジフルオロ化合物の製造方法
WO1997017974A1 (fr) 1995-11-14 1997-05-22 Toray Industries, Inc. Depresseur oculaire
TW416953B (en) 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
AUPO440696A0 (en) 1996-12-30 1997-01-23 Fujisawa Pharmaceutical Co., Ltd. New use
WO1998041209A1 (en) 1997-03-14 1998-09-24 Toray Industries, Inc. Protective agents for cells constituting nervous system
IT1299191B1 (it) * 1998-06-23 2000-02-29 Sigma Tau Healthscience Spa Composizione atta a prevenire e trattare l'osteoporosi e le alterazioni legate alla menopausa
WO2000024727A1 (fr) 1998-10-23 2000-05-04 Toray Industries, Inc. DERIVE PGI2 DE 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE ET MEDICAMENTS CONTENANT LEDIT DERIVE
EP1409455B1 (en) * 2001-07-16 2006-01-04 F. Hoffmann-La Roche Ag Prostaglandin analogues-as ep4 receptor agonists
BR0308166A (pt) * 2002-03-05 2005-01-18 Ono Pharmaceutical Co Compostos de derivados de 8-azaprostaglandina e drogas contendo os compostos como o ingrediente ativo
WO2003103664A1 (en) 2002-06-06 2003-12-18 Merck Frosst Canada & Co. 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases
JP5007169B2 (ja) 2007-02-20 2012-08-22 カルソニックカンセイ株式会社 電動コンプレッサ
EP1988087A1 (en) 2007-03-28 2008-11-05 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of autoimmune diseases
JP2009168193A (ja) 2008-01-18 2009-07-30 Nachi Fujikoshi Corp 遊星歯車減速機
EP2343292B1 (en) * 2008-09-10 2014-08-06 Asahi Glass Company, Limited Novel prostaglandin i2 derivative

Also Published As

Publication number Publication date
JP5468007B2 (ja) 2014-04-09
CA2736039A1 (en) 2010-03-18
KR101645752B1 (ko) 2016-08-04
MX2011002573A (es) 2011-07-28
CA2736039C (en) 2016-06-07
US20110098481A1 (en) 2011-04-28
RU2011113967A (ru) 2012-10-27
ES2522971T3 (es) 2014-11-19
BRPI0918134B1 (pt) 2019-02-12
US20150018401A1 (en) 2015-01-15
AU2009292555B2 (en) 2014-05-29
US20140128441A1 (en) 2014-05-08
EP2343292B1 (en) 2014-08-06
RU2509768C2 (ru) 2014-03-20
US9034906B2 (en) 2015-05-19
EP2343292A1 (en) 2011-07-13
PT2343292E (pt) 2014-11-04
PL2343292T3 (pl) 2015-01-30
AU2009292555A1 (en) 2010-03-18
US20130072530A1 (en) 2013-03-21
KR20110051286A (ko) 2011-05-17
US8394844B2 (en) 2013-03-12
CN102209719A (zh) 2011-10-05
WO2010029925A1 (ja) 2010-03-18
DK2343292T3 (da) 2014-11-03
CN102209719B (zh) 2014-05-14
US8877787B2 (en) 2014-11-04
EP2343292A4 (en) 2012-03-21
US8691857B2 (en) 2014-04-08
JPWO2010029925A1 (ja) 2012-02-02

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B07E Notice of approval relating to section 229 industrial property law
B07A Technical examination (opinion): publication of technical examination (opinion)
B25D Requested change of name of applicant approved

Owner name: KAKEN PHARMACEUTICAL CO., LTD (JP) ; AGC INC. (JP)

B09A Decision: intention to grant
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/09/2009, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/09/2009, OBSERVADAS AS CONDICOES LEGAIS

B25A Requested transfer of rights approved

Owner name: AGC INC. (JP)

B25G Requested change of headquarter approved

Owner name: AGC INC. (JP)