BRPI0915714A2 - forma cristalina de posaconazol - Google Patents
forma cristalina de posaconazolInfo
- Publication number
- BRPI0915714A2 BRPI0915714A2 BRPI0915714A BRPI0915714A BRPI0915714A2 BR PI0915714 A2 BRPI0915714 A2 BR PI0915714A2 BR PI0915714 A BRPI0915714 A BR PI0915714A BR PI0915714 A BRPI0915714 A BR PI0915714A BR PI0915714 A2 BRPI0915714 A2 BR PI0915714A2
- Authority
- BR
- Brazil
- Prior art keywords
- posaconazole
- crystalline form
- crystalline
- Prior art date
Links
- RAGOYPUPXAKGKH-XAKZXMRKSA-N posaconazole Chemical compound O=C1N([C@H]([C@H](C)O)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@H]3C[C@@](CN4N=CN=C4)(OC3)C=3C(=CC(F)=CC=3)F)=CC=2)C=C1 RAGOYPUPXAKGKH-XAKZXMRKSA-N 0.000 title 1
- 229960001589 posaconazole Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13385208P | 2008-07-03 | 2008-07-03 | |
| EP08159600A EP2141159A1 (en) | 2008-07-03 | 2008-07-03 | A Crystalline form of posaconazole |
| PCT/EP2009/057975 WO2010000668A1 (en) | 2008-07-03 | 2009-06-25 | A crystalline form of posaconazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0915714A2 true BRPI0915714A2 (pt) | 2015-10-27 |
Family
ID=39951578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0915714A BRPI0915714A2 (pt) | 2008-07-03 | 2009-06-25 | forma cristalina de posaconazol |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8435998B2 (pt) |
| EP (2) | EP2141159A1 (pt) |
| KR (1) | KR101639456B1 (pt) |
| CN (1) | CN102066363B (pt) |
| AU (1) | AU2009265848B2 (pt) |
| BR (1) | BRPI0915714A2 (pt) |
| CA (1) | CA2728170C (pt) |
| DK (1) | DK2318396T5 (pt) |
| ES (1) | ES2397592T3 (pt) |
| HR (1) | HRP20130026T2 (pt) |
| IL (1) | IL209196A (pt) |
| MX (1) | MX2010014041A (pt) |
| PL (1) | PL2318396T3 (pt) |
| RS (1) | RS52673B (pt) |
| SI (1) | SI2318396T1 (pt) |
| WO (1) | WO2010000668A1 (pt) |
| ZA (1) | ZA201008019B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| WO2011003992A1 (en) * | 2009-07-09 | 2011-01-13 | Sandoz Ag | A crystalline form of posaconazole |
| RU2585760C2 (ru) * | 2010-05-19 | 2016-06-10 | Сандоз Аг | Способ получения хиральных триазолонов |
| MX337804B (es) * | 2010-05-19 | 2016-03-18 | Sandoz Ag | Proceso para la preparacion de hidrazinas quirales. |
| BR112012029226A2 (pt) | 2010-05-19 | 2015-10-20 | Sandoz Ag | processo para a preparação de um composto quiral, composto quiral cristalino, sal de hcl do composto quiral cristalino, composto quiral e uso do composto |
| MX2012013331A (es) | 2010-05-19 | 2013-02-01 | Sandoz Ag | Purificacion de posaconazol y de intermediarios de posaconazol. |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| CN104379132A (zh) * | 2012-06-14 | 2015-02-25 | 桑多斯股份公司 | 包含结晶泊沙康唑的药物组合物 |
| CN105579448B (zh) * | 2013-07-25 | 2018-12-21 | 桑多斯股份公司 | 制备泊沙康唑的晶型iv的改进方法 |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132114A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| DE102014203040A1 (de) | 2014-02-19 | 2015-08-20 | Carl Zeiss Smt Gmbh | Beleuchtungssystem einer mikrolithographischen Projektionsbelichtungsanlage und Verfahren zum Betreiben eines solchen |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| CN105622590B (zh) * | 2014-10-30 | 2019-08-20 | 上海美悦生物科技发展有限公司 | 一种泊沙康唑的晶型vi及其制备方法 |
| WO2017025292A1 (en) | 2015-08-08 | 2017-02-16 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant formulation containing posaconazole |
| EP4424308A2 (en) | 2016-02-26 | 2024-09-04 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| SG10202105118WA (en) * | 2016-11-28 | 2021-06-29 | Cellix Bio Private Ltd | Compositions and methods for the treatment of fungal infections |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| CN106883221A (zh) * | 2017-04-17 | 2017-06-23 | 兰州大学 | 一种无定形泊沙康唑及其制备方法 |
| CN107625729A (zh) * | 2017-09-29 | 2018-01-26 | 重庆华邦制药有限公司 | 泊沙康唑口服混悬液及其制备方法 |
| JP2022542403A (ja) * | 2019-07-31 | 2022-10-03 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン | ポサコナゾールの共結晶、それを作製および使用する方法 |
| GB201917867D0 (en) * | 2019-12-06 | 2020-01-22 | Pulmocide Ltd | Polymorphs |
| WO2022034232A1 (en) | 2020-08-13 | 2022-02-17 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| AU2022324717A1 (en) | 2021-11-25 | 2024-06-13 | Alfred E. Tiefenbacher (Gmbh Und Co. Kg) | Granules containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4533254A (en) * | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
| DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| ES2159623T3 (es) * | 1993-12-21 | 2001-10-16 | Schering Corp | Antifungicos de tetrahidrofurano. |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| CA2197672C (en) | 1995-06-02 | 2011-05-17 | Anil K. Saksena | Tetrahydrofuran antifungals |
| US5834472A (en) | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US5972381A (en) | 1996-06-28 | 1999-10-26 | Schering Corporation | Solid solution of an antifungal agent with enhanced bioavailability |
| DE69822859T2 (de) * | 1997-10-07 | 2005-01-27 | Schering Corp. | Krytallinischer fungizider polymorph |
| US6713481B1 (en) | 1997-10-17 | 2004-03-30 | David R. Andrews | Crystalline antifungal polymorph |
| HUP0400856A3 (en) | 2001-04-03 | 2012-09-28 | Merck Sharp & Dohme | Antifungal composition |
| US7563748B2 (en) | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
| US20060009469A1 (en) | 2004-05-28 | 2006-01-12 | Leonore Witchey-Lakshmanan | Particulate-stabilized injectable pharmacutical compositions of posaconazole |
| AR049063A1 (es) | 2004-05-28 | 2006-06-21 | Schering Corp | Composiciones farmaceuticas inyectables de posaconazol con particulas estabilizadas |
| WO2006000020A1 (en) | 2004-06-29 | 2006-01-05 | European Nickel Plc | Improved leaching of base metals |
| CN101227857B (zh) | 2005-06-29 | 2011-10-19 | 电脑医师有限公司 | 具有导电桥的传感器组件 |
| US20070281011A1 (en) | 2006-05-30 | 2007-12-06 | Elan Pharma International Ltd. | Nanoparticulate posaconazole formulations |
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| WO2011000020A1 (en) | 2009-06-12 | 2011-01-06 | Sbc Research Pty Ltd | Enhanced method of detection |
| WO2011003992A1 (en) | 2009-07-09 | 2011-01-13 | Sandoz Ag | A crystalline form of posaconazole |
-
2008
- 2008-07-03 EP EP08159600A patent/EP2141159A1/en not_active Withdrawn
-
2009
- 2009-06-25 CA CA2728170A patent/CA2728170C/en not_active Expired - Fee Related
- 2009-06-25 DK DK09772368.8T patent/DK2318396T5/da active
- 2009-06-25 BR BRPI0915714A patent/BRPI0915714A2/pt not_active Application Discontinuation
- 2009-06-25 WO PCT/EP2009/057975 patent/WO2010000668A1/en active Application Filing
- 2009-06-25 PL PL09772368T patent/PL2318396T3/pl unknown
- 2009-06-25 ES ES09772368T patent/ES2397592T3/es active Active
- 2009-06-25 RS RS20130006A patent/RS52673B/en unknown
- 2009-06-25 SI SI200930468T patent/SI2318396T1/sl unknown
- 2009-06-25 MX MX2010014041A patent/MX2010014041A/es active IP Right Grant
- 2009-06-25 CN CN200980123512.4A patent/CN102066363B/zh not_active Expired - Fee Related
- 2009-06-25 EP EP09772368.8A patent/EP2318396B9/en active Active
- 2009-06-25 US US12/993,351 patent/US8435998B2/en active Active
- 2009-06-25 AU AU2009265848A patent/AU2009265848B2/en not_active Ceased
- 2009-06-25 KR KR1020107028674A patent/KR101639456B1/ko active IP Right Grant
-
2010
- 2010-11-08 IL IL209196A patent/IL209196A/en active IP Right Grant
- 2010-11-09 ZA ZA2010/08019A patent/ZA201008019B/en unknown
-
2013
- 2013-01-15 HR HRP20130026AT patent/HRP20130026T2/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2397592T9 (es) | 2013-08-30 |
| ES2397592T3 (es) | 2013-03-08 |
| US20110065722A1 (en) | 2011-03-17 |
| ZA201008019B (en) | 2012-02-29 |
| EP2318396B1 (en) | 2012-10-24 |
| CN102066363A (zh) | 2011-05-18 |
| IL209196A (en) | 2015-08-31 |
| EP2318396A1 (en) | 2011-05-11 |
| RS52673B (en) | 2013-06-28 |
| CA2728170C (en) | 2017-02-14 |
| PL2318396T3 (pl) | 2013-03-29 |
| CN102066363B (zh) | 2014-11-05 |
| WO2010000668A1 (en) | 2010-01-07 |
| IL209196A0 (en) | 2011-01-31 |
| EP2318396B9 (en) | 2013-05-29 |
| EP2141159A1 (en) | 2010-01-06 |
| DK2318396T5 (da) | 2013-09-02 |
| CA2728170A1 (en) | 2010-01-07 |
| MX2010014041A (es) | 2011-03-03 |
| AU2009265848B2 (en) | 2014-02-20 |
| DK2318396T3 (da) | 2013-02-04 |
| HRP20130026T1 (hr) | 2013-02-28 |
| SI2318396T1 (sl) | 2013-02-28 |
| KR101639456B1 (ko) | 2016-07-13 |
| KR20110025763A (ko) | 2011-03-11 |
| US8435998B2 (en) | 2013-05-07 |
| HRP20130026T2 (en) | 2013-10-11 |
| AU2009265848A1 (en) | 2010-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |