BRPI0820888A2 - Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos. - Google Patents

Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos.

Info

Publication number
BRPI0820888A2
BRPI0820888A2 BRPI0820888-3A BRPI0820888A BRPI0820888A2 BR PI0820888 A2 BRPI0820888 A2 BR PI0820888A2 BR PI0820888 A BRPI0820888 A BR PI0820888A BR PI0820888 A2 BRPI0820888 A2 BR PI0820888A2
Authority
BR
Brazil
Prior art keywords
quaternization
pharmaceuticals
permeability
solubility
improve
Prior art date
Application number
BRPI0820888-3A
Other languages
English (en)
Inventor
Peter Langguth
Stefan Grube
Holger Frey
Boris Obermeier
Original Assignee
Evonik Roehm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh filed Critical Evonik Roehm Gmbh
Publication of BRPI0820888A2 publication Critical patent/BRPI0820888A2/pt
Publication of BRPI0820888B1 publication Critical patent/BRPI0820888B1/pt
Publication of BRPI0820888B8 publication Critical patent/BRPI0820888B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/34Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F26/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F26/02Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0820888A 2007-12-13 2008-12-12 Copolímero de metacrilato de aminoalquila e, seu uso e seu método de produção, e formulação farmacêutica BRPI0820888B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007060175A DE102007060175A1 (de) 2007-12-13 2007-12-13 Quartärnisierung des Zusatzstoffs Aminoalkyl Methacrylat Copolymer E zur Verbesserung der Permeabilität und Löslichkeit von Arzneistoffen
DE102007060175.3 2007-12-13
PCT/EP2008/010585 WO2009074336A1 (de) 2007-12-13 2008-12-12 Quartärnisierung des zusatzstoffs aminoalkyl methacrylat copolymer e zur verbesserung der permeabilität und löslichkeit von arzneistoffen

Publications (3)

Publication Number Publication Date
BRPI0820888A2 true BRPI0820888A2 (pt) 2015-06-16
BRPI0820888B1 BRPI0820888B1 (pt) 2019-03-26
BRPI0820888B8 BRPI0820888B8 (pt) 2022-07-05

Family

ID=40339608

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0820888A BRPI0820888B8 (pt) 2007-12-13 2008-12-12 Copolímero de metacrilato de aminoalquila e, seu uso e seu método de produção, e formulação farmacêutica

Country Status (15)

Country Link
US (1) US8399523B2 (pt)
EP (1) EP2219676B1 (pt)
JP (1) JP5645668B2 (pt)
KR (1) KR101573554B1 (pt)
CN (2) CN101896207A (pt)
BR (1) BRPI0820888B8 (pt)
CA (1) CA2708431C (pt)
DE (1) DE102007060175A1 (pt)
ES (1) ES2562444T3 (pt)
HU (1) HUE026739T2 (pt)
IL (1) IL206016A (pt)
MX (1) MX2010006354A (pt)
PL (1) PL2219676T3 (pt)
SI (1) SI2219676T1 (pt)
WO (1) WO2009074336A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102470175B (zh) * 2009-07-30 2014-06-18 赢创罗姆有限公司 含氨基(甲基)丙烯酸酯聚合物或共聚物的水性碳酸化介质
EP3916029A1 (en) 2020-05-28 2021-12-01 Evonik Operations GmbH Novel methacrylate copolymer and compositions comprising it
EP3915543A1 (en) 2020-05-28 2021-12-01 Evonik Operations GmbH Solid self-nanoemulsifying drug delivery system (s-snedds)
EP4320233A1 (en) 2021-04-07 2024-02-14 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179549A (en) * 1974-11-14 1979-12-18 Petrolite Corporation Quaternary ammonium adducts of polymerizable tertiary ammonium salts and acrylamide
JPS61174202A (ja) * 1985-01-29 1986-08-05 Mitsubishi Yuka Fine Chem Co Ltd 水溶性の感光性樹脂の製造方法
JPH075683B2 (ja) * 1986-09-09 1995-01-25 三菱レイヨン株式会社 帯電防止性に優れたメタクリル樹脂キヤスト板の製造方法
JP2520659B2 (ja) * 1987-09-10 1996-07-31 東京瓦斯株式会社 センサ―架台の海底着座方法及び装置
RU2155605C2 (ru) * 1994-04-22 2000-09-10 Яманоути Фармасьютикал Ко., Лтд. Система, выделяющая лекарство, специфичное в отношении толстой кишки
CN1237199A (zh) * 1996-09-19 1999-12-01 普罗格特-甘布尔公司 具有增强性能的织物柔软剂
IT1294748B1 (it) * 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
FR2804122B1 (fr) * 2000-01-24 2002-02-22 Atofina Dispersions aqueuses sans sel de (co)polymeres hydrosolubles a base de monomeres cationiques, leur procede de fabrication et leurs applications
DE10013029A1 (de) * 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
MXPA03000520A (es) 2000-07-17 2003-10-06 Yamanouchi Pharma Co Ltd Composicion farmaceutica mejorada en absorbabilidad peroral..
US20050019381A1 (en) * 2001-01-29 2005-01-27 Hans-Ulrich Petereit Binding agent which is stable in storage and used for pharmaceutical applications
GB0114197D0 (en) 2001-06-11 2001-08-01 Syngenta Ltd Reactive polymeric surfactants
ES2280582T3 (es) * 2001-09-19 2007-09-16 Elan Pharma International Limited Formulaciones de insulina en nanoparticulas.
US6838078B2 (en) * 2002-01-16 2005-01-04 3M Innovative Properties Company Film-forming compositions and methods
GB0228537D0 (en) * 2002-12-06 2003-01-15 Syngenta Ltd Particulate suspensions
GB0229147D0 (en) * 2002-12-13 2003-01-15 Unilever Plc Polymers and laundry detergent compositions containing them
US7087174B2 (en) * 2004-04-08 2006-08-08 Nalco Company Enhanced recovery of useful coal, potassium chloride and borax from screen bowl centrifuge
JP4362093B2 (ja) * 2004-08-06 2009-11-11 大日本印刷株式会社 帯電防止膜形成用の電離放射線硬化性組成物と帯電防止膜および帯電防止膜を備えた構造体
JP2006161259A (ja) * 2004-11-12 2006-06-22 Harima Chem Inc カチオン性表面サイズ剤、及び当該サイズ剤を塗工した紙
EP1810668A1 (en) * 2006-01-23 2007-07-25 LEK Pharmaceuticals D.D. Coated formulations containing tolterodine tartrate

Also Published As

Publication number Publication date
PL2219676T3 (pl) 2016-05-31
ES2562444T3 (es) 2016-03-04
HUE026739T2 (en) 2016-07-28
WO2009074336A1 (de) 2009-06-18
IL206016A (en) 2015-11-30
KR20100106380A (ko) 2010-10-01
KR101573554B1 (ko) 2015-12-01
CN101896207A (zh) 2010-11-24
SI2219676T1 (sl) 2016-03-31
CN103897079B (zh) 2017-08-18
CA2708431A1 (en) 2009-06-18
BRPI0820888B1 (pt) 2019-03-26
EP2219676B1 (de) 2015-12-09
US20100286288A1 (en) 2010-11-11
IL206016A0 (en) 2010-11-30
CA2708431C (en) 2016-01-26
EP2219676A1 (de) 2010-08-25
US8399523B2 (en) 2013-03-19
BRPI0820888B8 (pt) 2022-07-05
JP5645668B2 (ja) 2014-12-24
DE102007060175A1 (de) 2009-06-18
JP2011506370A (ja) 2011-03-03
CN103897079A (zh) 2014-07-02
MX2010006354A (es) 2010-12-20

Similar Documents

Publication Publication Date Title
NL300891I2 (nl) Lotilaner en zouten daarvan
DE602006008264D1 (de) Turbo-Auflader
DE602008001431D1 (de) Lösliche Polythiophenderivate
BRPI1013023A2 (pt) "bolsa solúvel em água"
BRPI0716253A2 (pt) glioxalaÇço de polÍmero de vinilamida
BRPI0814314A2 (pt) Microbiocidas
BRPI0907064A2 (pt) "métodos e sistemas"
DK1973775T3 (da) Bølgeenergi
DE602007011183D1 (de) Hydrazinfunktionalisiertes Polymer
BRPI0717235A2 (pt) Dispositivo para pig
DK2215308T3 (da) Højvandsklap
DE502007001779D1 (de) Anhängekupplung
BRPI1014821A2 (pt) "inibidores de replicação de hiv"
DK2193795T3 (da) Latanoprostholdig vandig farmaceutisk sammensætning
FR22C1045I2 (fr) Conjugués protéine-polymère
BRPI0813781A2 (pt) microbiocidas
BRPI0820888A2 (pt) Quaternização do copolímero aditivo metacrilato de aminoalquila e para melhorar a permeabilidade e a solubilidade de produtos farmacêuticos.
FI20065612A0 (fi) Sivurajoitin
IT1398018B1 (it) Obice rimorchiato
BRPI0815252A2 (pt) "aparato marcador"
FI20075579A (fi) Pitolaite
DE502007000195D1 (de) Absicherungsvorrichtung
FR2947064B1 (fr) Dispositif d'holographie
FR2899452B1 (fr) Gondole contreventee
ITCZ20070007A1 (it) Apparecchiouniversal intelligent reader uir - evidenziatore intelligente

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/03/2019, OBSERVADAS AS CONDICOES LEGAIS.

B25D Requested change of name of applicant approved

Owner name: ROEHM GMBH (DE)

B25G Requested change of headquarter approved

Owner name: ROEHM GMBH (DE)

B25A Requested transfer of rights approved

Owner name: EVONIK DEGUSSA GMBH (DE)

B25D Requested change of name of applicant approved

Owner name: EVONIK OPERATIONS GMBH (DE)