BRPI0820300A2 - Processo de preparo de compostos morfínicos - Google Patents
Processo de preparo de compostos morfínicosInfo
- Publication number
- BRPI0820300A2 BRPI0820300A2 BRPI0820300-8A BRPI0820300A BRPI0820300A2 BR PI0820300 A2 BRPI0820300 A2 BR PI0820300A2 BR PI0820300 A BRPI0820300 A BR PI0820300A BR PI0820300 A2 BRPI0820300 A2 BR PI0820300A2
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- morphine compounds
- morphine
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
- C07B63/02—Purification; Separation; Stabilisation; Use of additives by treatment giving rise to a chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0758923A FR2923484B1 (fr) | 2007-11-09 | 2007-11-09 | Procede de preparation de composes morphiniques |
US2194908P | 2008-01-18 | 2008-01-18 | |
PCT/FR2008/001558 WO2009092912A1 (fr) | 2007-11-09 | 2008-11-06 | Procede de preparation de composes morphiniques |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0820300A2 true BRPI0820300A2 (pt) | 2015-05-19 |
Family
ID=39099817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0820300-8A BRPI0820300A2 (pt) | 2007-11-09 | 2008-11-06 | Processo de preparo de compostos morfínicos |
Country Status (21)
Country | Link |
---|---|
US (1) | US8455509B2 (pt) |
EP (1) | EP2231673A1 (pt) |
JP (1) | JP2011503040A (pt) |
KR (1) | KR20100083815A (pt) |
CN (1) | CN101868462A (pt) |
AR (1) | AR069225A1 (pt) |
AU (1) | AU2008348675A1 (pt) |
BR (1) | BRPI0820300A2 (pt) |
CA (1) | CA2705251A1 (pt) |
CL (1) | CL2008003333A1 (pt) |
EA (1) | EA017287B1 (pt) |
FR (1) | FR2923484B1 (pt) |
IL (1) | IL205601A0 (pt) |
MA (1) | MA31982B1 (pt) |
MX (1) | MX2010005124A (pt) |
NZ (1) | NZ585218A (pt) |
SG (1) | SG186591A1 (pt) |
TW (1) | TW200936592A (pt) |
UY (1) | UY31460A1 (pt) |
WO (1) | WO2009092912A1 (pt) |
ZA (1) | ZA201003241B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8829020B2 (en) | 2009-07-16 | 2014-09-09 | Mallinckrodt Llc | Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers |
CN102174049A (zh) * | 2011-03-11 | 2011-09-07 | 山东新华制药股份有限公司 | 一种盐酸纳洛酮成盐的制备工艺 |
ES2622342T3 (es) * | 2012-02-08 | 2017-07-06 | Mallinckrodt Llc | Proceso en un solo recipiente para producir 6-hidroxilo nal-opiáceos |
ES2846735T3 (es) | 2013-03-15 | 2021-07-29 | Johnson Matthey Plc | Solvato metanólico de sulfato de morfina, procedimientos para hacer el mismo y las composiciones relacionadas y métodos de tratamiento del dolor |
CN103408553B (zh) * | 2013-08-20 | 2016-02-03 | 宜昌人福药业有限责任公司 | 一种氢吗啡酮酸式盐的精制工艺 |
CN104230945B (zh) * | 2014-08-23 | 2016-05-18 | 成都天台山制药有限公司 | 盐酸纳洛酮的合成方法 |
US10807995B2 (en) | 2018-07-13 | 2020-10-20 | Alkermes Pharma Ireland Limited | Thienothiophene compounds for long-acting injectable compositions and related methods |
US10799496B2 (en) | 2018-07-13 | 2020-10-13 | Alkermes Pharma Ireland Limited | Naphthylenyl compounds for long-acting injectable compositions and related methods |
US10975099B2 (en) | 2018-11-05 | 2021-04-13 | Alkermes Pharma Ireland Limited | Thiophene compounds for long-acting injectable compositions and related methods |
CN110724155A (zh) * | 2019-11-11 | 2020-01-24 | 北京华素制药股份有限公司 | 一种羟考酮羟醛二聚体的制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0421149D0 (en) | 2004-09-23 | 2004-10-27 | Johnson Matthey Plc | Preparation of oxycodone |
WO2006084389A1 (de) * | 2005-02-11 | 2006-08-17 | Cilag Ltd. | Verfahren zur reinigung von noroxymorphon-verbindungen |
WO2006094672A1 (en) * | 2005-03-04 | 2006-09-14 | Euro-Celtique S.A. | Method of reducing alpha, beta unsaturated ketones in opioid compositions |
CN101346384B (zh) * | 2005-11-22 | 2012-07-04 | 控制化学品公司 | 用于降低羟考酮和其它组分中杂质迈克尔受体水平的方法 |
EP1994034B1 (en) * | 2006-03-02 | 2009-11-11 | Mallinckrodt, Inc. | Processes for preparing morphinan-6-one products with low levels of alpha, beta-unsaturated ketone compounds |
CN104761561A (zh) * | 2006-12-04 | 2015-07-08 | 诺拉姆科有限公司 | 减少羟考酮碱中杂质的方法 |
US7906647B2 (en) * | 2006-12-04 | 2011-03-15 | Noramco, Inc. | Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone |
GB0624880D0 (en) * | 2006-12-14 | 2007-01-24 | Johnson Matthey Plc | Improved method for making analgesics |
-
2007
- 2007-11-09 FR FR0758923A patent/FR2923484B1/fr not_active Expired - Fee Related
-
2008
- 2008-11-06 EP EP08871482A patent/EP2231673A1/fr not_active Withdrawn
- 2008-11-06 BR BRPI0820300-8A patent/BRPI0820300A2/pt not_active IP Right Cessation
- 2008-11-06 CN CN200880115278A patent/CN101868462A/zh active Pending
- 2008-11-06 NZ NZ585218A patent/NZ585218A/xx not_active IP Right Cessation
- 2008-11-06 CA CA2705251A patent/CA2705251A1/fr not_active Abandoned
- 2008-11-06 WO PCT/FR2008/001558 patent/WO2009092912A1/fr active Application Filing
- 2008-11-06 JP JP2010532634A patent/JP2011503040A/ja active Pending
- 2008-11-06 SG SG2012079125A patent/SG186591A1/en unknown
- 2008-11-06 AU AU2008348675A patent/AU2008348675A1/en not_active Abandoned
- 2008-11-06 MX MX2010005124A patent/MX2010005124A/es active IP Right Grant
- 2008-11-06 EA EA201070589A patent/EA017287B1/ru not_active IP Right Cessation
- 2008-11-06 KR KR1020107010076A patent/KR20100083815A/ko not_active Application Discontinuation
- 2008-11-07 UY UY31460A patent/UY31460A1/es not_active Application Discontinuation
- 2008-11-07 TW TW097143241A patent/TW200936592A/zh unknown
- 2008-11-07 CL CL2008003333A patent/CL2008003333A1/es unknown
- 2008-11-07 AR ARP080104878A patent/AR069225A1/es not_active Application Discontinuation
-
2010
- 2010-05-05 US US12/774,156 patent/US8455509B2/en active Active
- 2010-05-06 IL IL205601A patent/IL205601A0/en unknown
- 2010-05-07 ZA ZA2010/03241A patent/ZA201003241B/en unknown
- 2010-06-07 MA MA32893A patent/MA31982B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
MX2010005124A (es) | 2010-05-27 |
JP2011503040A (ja) | 2011-01-27 |
KR20100083815A (ko) | 2010-07-22 |
NZ585218A (en) | 2012-08-31 |
MA31982B1 (fr) | 2011-01-03 |
IL205601A0 (en) | 2010-11-30 |
US8455509B2 (en) | 2013-06-04 |
EP2231673A1 (fr) | 2010-09-29 |
ZA201003241B (en) | 2011-08-31 |
EA017287B1 (ru) | 2012-11-30 |
TW200936592A (en) | 2009-09-01 |
UY31460A1 (es) | 2009-07-17 |
FR2923484A1 (fr) | 2009-05-15 |
US20100256176A1 (en) | 2010-10-07 |
CA2705251A1 (fr) | 2009-07-30 |
FR2923484B1 (fr) | 2012-11-09 |
SG186591A1 (en) | 2013-01-30 |
WO2009092912A1 (fr) | 2009-07-30 |
EA201070589A1 (ru) | 2010-10-29 |
CN101868462A (zh) | 2010-10-20 |
AU2008348675A1 (en) | 2009-07-30 |
AR069225A1 (es) | 2010-01-06 |
CL2008003333A1 (es) | 2010-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |