BRPI0810522B8 - compostos miméticos diazo bicíclicos de smac, composição farmacêutica e kit compreendendo ditos compostos e uso dos mesmos para o tratamento de câncer - Google Patents

compostos miméticos diazo bicíclicos de smac, composição farmacêutica e kit compreendendo ditos compostos e uso dos mesmos para o tratamento de câncer

Info

Publication number
BRPI0810522B8
BRPI0810522B8 BRPI0810522A BRPI0810522A BRPI0810522B8 BR PI0810522 B8 BRPI0810522 B8 BR PI0810522B8 BR PI0810522 A BRPI0810522 A BR PI0810522A BR PI0810522 A BRPI0810522 A BR PI0810522A BR PI0810522 B8 BRPI0810522 B8 BR PI0810522B8
Authority
BR
Brazil
Prior art keywords
compounds
diazo
bicyclic
smac
mimetic
Prior art date
Application number
BRPI0810522A
Other languages
English (en)
Portuguese (pt)
Inventor
Sun Haiying
Lu Jianfeng
Cai Qian
Wang Shaomeng
Qiu Su
Peng Yuefeng
Nikolovska-Coleska Zaneta
Original Assignee
Univ Michigan Regents
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39864640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0810522(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Michigan Regents filed Critical Univ Michigan Regents
Publication of BRPI0810522A2 publication Critical patent/BRPI0810522A2/pt
Publication of BRPI0810522B1 publication Critical patent/BRPI0810522B1/pt
Publication of BRPI0810522B8 publication Critical patent/BRPI0810522B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
BRPI0810522A 2007-04-13 2008-04-14 compostos miméticos diazo bicíclicos de smac, composição farmacêutica e kit compreendendo ditos compostos e uso dos mesmos para o tratamento de câncer BRPI0810522B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92334807P 2007-04-13 2007-04-13
PCT/US2008/060215 WO2008128171A2 (en) 2007-04-13 2008-04-14 Diazo bicyclic smac mimetics and the uses thereof

Publications (3)

Publication Number Publication Date
BRPI0810522A2 BRPI0810522A2 (pt) 2014-10-21
BRPI0810522B1 BRPI0810522B1 (pt) 2020-02-04
BRPI0810522B8 true BRPI0810522B8 (pt) 2021-05-25

Family

ID=39864640

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810522A BRPI0810522B8 (pt) 2007-04-13 2008-04-14 compostos miméticos diazo bicíclicos de smac, composição farmacêutica e kit compreendendo ditos compostos e uso dos mesmos para o tratamento de câncer

Country Status (22)

Country Link
US (2) US8278293B2 (Direct)
EP (1) EP2139490B1 (Direct)
JP (1) JP5416089B2 (Direct)
KR (1) KR101081685B1 (Direct)
CN (1) CN101686981B (Direct)
AU (1) AU2008240119B2 (Direct)
BR (1) BRPI0810522B8 (Direct)
CA (1) CA2683318C (Direct)
CY (1) CY1115735T1 (Direct)
DK (1) DK2139490T3 (Direct)
EA (1) EA017797B1 (Direct)
ES (1) ES2504216T3 (Direct)
HR (1) HRP20140885T1 (Direct)
HU (1) HUE024142T2 (Direct)
IL (1) IL201474A (Direct)
MX (1) MX2009011069A (Direct)
NZ (1) NZ580468A (Direct)
PL (1) PL2139490T3 (Direct)
PT (1) PT2139490E (Direct)
SI (1) SI2139490T1 (Direct)
WO (1) WO2008128171A2 (Direct)
ZA (1) ZA200907055B (Direct)

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Also Published As

Publication number Publication date
NZ580468A (en) 2012-02-24
HRP20140885T1 (hr) 2014-11-21
US20120309961A1 (en) 2012-12-06
DK2139490T3 (da) 2014-09-08
CN101686981A (zh) 2010-03-31
WO2008128171A3 (en) 2008-12-11
JP5416089B2 (ja) 2014-02-12
BRPI0810522B1 (pt) 2020-02-04
AU2008240119B2 (en) 2012-04-05
US20100273812A1 (en) 2010-10-28
PT2139490E (pt) 2014-10-08
EP2139490B1 (en) 2014-07-02
HUE024142T2 (en) 2016-02-29
CA2683318A1 (en) 2008-10-23
BRPI0810522A2 (pt) 2014-10-21
US8664212B2 (en) 2014-03-04
KR101081685B1 (ko) 2011-11-09
EP2139490A4 (en) 2010-10-27
AU2008240119A1 (en) 2008-10-23
HK1141456A1 (en) 2010-11-12
JP2010523722A (ja) 2010-07-15
IL201474A0 (en) 2010-05-31
CY1115735T1 (el) 2017-01-25
MX2009011069A (es) 2009-12-03
WO2008128171A2 (en) 2008-10-23
CA2683318C (en) 2012-10-30
EP2139490A2 (en) 2010-01-06
ES2504216T3 (es) 2014-10-08
IL201474A (en) 2015-11-30
KR20100005213A (ko) 2010-01-14
US8278293B2 (en) 2012-10-02
CN101686981B (zh) 2013-04-10
ZA200907055B (en) 2011-03-30
PL2139490T3 (pl) 2014-11-28
EA200901400A1 (ru) 2010-04-30
EA017797B1 (ru) 2013-03-29
SI2139490T1 (sl) 2014-11-28

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