BRPI0809330B8 - uso de um ou mais oligômeros de ácido láctico, e, composição farmacêutica - Google Patents

uso de um ou mais oligômeros de ácido láctico, e, composição farmacêutica

Info

Publication number
BRPI0809330B8
BRPI0809330B8 BRPI0809330A BRPI0809330A BRPI0809330B8 BR PI0809330 B8 BRPI0809330 B8 BR PI0809330B8 BR PI0809330 A BRPI0809330 A BR PI0809330A BR PI0809330 A BRPI0809330 A BR PI0809330A BR PI0809330 B8 BRPI0809330 B8 BR PI0809330B8
Authority
BR
Brazil
Prior art keywords
lactic acid
acid oligomers
infection
pharmaceutical composition
hpv
Prior art date
Application number
BRPI0809330A
Other languages
English (en)
Portuguese (pt)
Inventor
Sjögren Christer
Batcheller Greg
Johnsson Jörgen
Sznitowska Malgorzat
Sterner Olov
Hedner Thomas
Schubert Werner
Original Assignee
Laccure Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laccure Ab filed Critical Laccure Ab
Publication of BRPI0809330A2 publication Critical patent/BRPI0809330A2/pt
Publication of BRPI0809330B1 publication Critical patent/BRPI0809330B1/pt
Publication of BRPI0809330B8 publication Critical patent/BRPI0809330B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0809330A 2007-03-30 2008-03-28 uso de um ou mais oligômeros de ácido láctico, e, composição farmacêutica BRPI0809330B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200700508 2007-03-30
DKPA200700508 2007-03-30
PCT/EP2008/002505 WO2008119518A1 (en) 2007-03-30 2008-03-28 Use of oligomers of lactic acid in the treatment of gynaecological disorders

Publications (3)

Publication Number Publication Date
BRPI0809330A2 BRPI0809330A2 (pt) 2014-09-09
BRPI0809330B1 BRPI0809330B1 (pt) 2019-12-17
BRPI0809330B8 true BRPI0809330B8 (pt) 2021-05-25

Family

ID=39494560

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0809330A BRPI0809330B8 (pt) 2007-03-30 2008-03-28 uso de um ou mais oligômeros de ácido láctico, e, composição farmacêutica

Country Status (19)

Country Link
US (3) US8425894B2 (enExample)
EP (2) EP2679222A1 (enExample)
JP (2) JP5409596B2 (enExample)
KR (1) KR101518014B1 (enExample)
CN (2) CN103830216B (enExample)
AU (1) AU2008234064B2 (enExample)
BR (1) BRPI0809330B8 (enExample)
CA (1) CA2681803C (enExample)
CY (1) CY1115310T1 (enExample)
DK (1) DK2142186T3 (enExample)
ES (1) ES2482190T3 (enExample)
HR (1) HRP20140559T1 (enExample)
MX (1) MX2009010445A (enExample)
PL (1) PL2142186T3 (enExample)
PT (1) PT2142186E (enExample)
RU (1) RU2459620C2 (enExample)
SI (1) SI2142186T1 (enExample)
WO (1) WO2008119518A1 (enExample)
ZA (1) ZA200907215B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2459620C2 (ru) 2007-03-30 2012-08-27 Лаккуре Аб Применение олигомеров молочной кислоты в лечении гинекологических расстройств
CN101797269B (zh) * 2010-03-23 2012-01-04 杨霞 一种调节女性阴道微生态的生理平衡液
RU2422147C1 (ru) * 2010-03-29 2011-06-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию" Способ лечения неспецифического аэробного вагинита
WO2012158779A1 (en) 2011-05-17 2012-11-22 Reprotect, Inc. Reusable intravaginal delivery device, system, and method
CN102274333A (zh) * 2011-08-22 2011-12-14 谢英华 一种治疗阴道炎的外洗中药
CN102579829B (zh) * 2012-03-06 2013-09-18 康莉 一种治疗牛放线菌病的中药组合物及其制备方法
WO2013187984A1 (en) 2012-06-13 2013-12-19 Evofem, Inc. Compositions and methods for enhancing the efficacy of contraceptive microbicides
BR112015001006B1 (pt) * 2012-07-16 2022-05-17 Laccure Ab Composição que compreende ácido lático oligomérico, e método para a preparação da composição
CN102885850B (zh) * 2012-10-15 2013-08-07 山东省医疗器械研究所 一种治疗阴道炎的多孔凝胶颗粒剂
NZ722215A (en) 2013-12-19 2019-02-22 Evofem Inc Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
US9895311B2 (en) * 2014-09-25 2018-02-20 Pharmiva Ab Foam-forming compositions and methods for delivering an active to a body cavity
DK3439633T3 (da) 2016-04-06 2021-12-20 Gedea Biotech Ab Glucono delta-lacton til behandling af vaginale svampeinfektioner
US10249017B2 (en) * 2016-08-11 2019-04-02 Intel Corporation Apparatus and method for shared resource partitioning through credit management
US20190209502A1 (en) * 2016-09-12 2019-07-11 Evofem, Inc. Combination gel for sexually transmitted infections
AU2017338748A1 (en) 2016-10-04 2019-05-02 Evofem Inc. Method of treatment and prevention of bacterial vaginosis
JP7219712B2 (ja) * 2016-10-13 2023-02-08 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド 膣送達のための凍結乾燥医薬組成物
LT3773501T (lt) * 2018-03-29 2024-01-10 The Materia Company Limited Intravaginalinis preparatas
US20220096349A1 (en) * 2019-02-13 2022-03-31 Miyoshi Oil & Fat Co., Ltd. Cosmetic compounding agent, cosmetic and production method thereof
WO2023165971A1 (en) 2022-03-01 2023-09-07 Laccure Ab Process for preparation of compositions of oligomers of lactic acid
EP4590289A4 (en) * 2023-07-07 2025-11-26 Changchun Sinobiomaterials Co Ltd MUSCLE ATROPHY

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431427A (en) * 1981-10-05 1984-02-14 University Of Delaware Tampons and their manufacture
US5274127A (en) * 1990-09-18 1993-12-28 Biopak Technology, Ltd. Lactide production from dehydration of aqueous lactic acid feed
JP2919912B2 (ja) 1990-05-23 1999-07-19 鐘紡株式会社 修飾プロテアーゼ及びその製造法
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
JPH07132127A (ja) 1993-06-17 1995-05-23 Mitsui Toatsu Chem Inc 生理用ナプキン
DE19506395A1 (de) 1994-02-24 1995-08-31 Ecological Chem Prod Zusammensetzung und Verfahren zum Verpacken feuchtigkeitshaltiger Lebensmittel
US5521278A (en) * 1994-08-18 1996-05-28 Ecological Chemical Products Integrated process for the manufacture of lactide
JP2864218B2 (ja) 1994-12-06 1999-03-03 株式会社日本製鋼所 ポリ乳酸共重合体の製造方法
US6369116B1 (en) 1995-06-02 2002-04-09 Oculex Pharmaceuticals, Inc. Composition and method for treating glaucoma
JPH09227388A (ja) * 1996-02-15 1997-09-02 Naganushi Tetsuaki 大腸癌、食道癌及び乳癌より選ばれた癌に用いる抗悪性腫瘍剤
AU2459497A (en) 1996-05-31 1998-01-05 Research And Development Institute, Inc. Urinary medical devices
US6229046B1 (en) 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
JP2000072680A (ja) * 1998-08-25 2000-03-07 Shiyumeidou:Kk 免疫機能調節剤
JP2001139476A (ja) * 1999-11-15 2001-05-22 Youichirou Naganushi 癌を含めた悪性新生物に用いる抗悪性腫瘍剤
RU2163810C1 (ru) * 2000-05-18 2001-03-10 Майорова Нина Федоровна Состав для удаления доброкачественных новообразований на коже и слизистых и способ его получения
WO2002055090A1 (fr) * 2001-01-12 2002-07-18 Amato Pharmaceutical Products,Ltd. Agents preventifs d'infections microbiennes
EP1362594A1 (en) 2001-01-24 2003-11-19 Amato Pharmaceutical Products, Ltd. Anti-stress agents
US20020177624A1 (en) 2001-03-16 2002-11-28 Calvin Hanna Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis
JP2002275256A (ja) * 2001-03-19 2002-09-25 Tendou Seiyaku Kk 乳酸オリゴマーの製造方法
WO2003016259A2 (de) 2001-08-16 2003-02-27 Pharmacon-Forschung Und Beratung Gmbh Milchsäureelemente enthaltende verbindungen, deren herstellung sowie deren verwendung als pharmazeutische wirkstoffe
WO2003039560A1 (en) * 2001-11-06 2003-05-15 Amato Pharmaceutical Products, Ltd. Antitumor agent containing lactic acid oligomer mixture
JP2004307561A (ja) * 2003-04-02 2004-11-04 Tendou Seiyaku Kk 環状乳酸オリゴマーの製造方法
CA2523740C (en) 2003-05-01 2012-05-15 Innogene Kalbiotech Pte Ltd Lactate containing pharmaceutical composition and uses thereof
JP4316299B2 (ja) * 2003-06-03 2009-08-19 学校法人東海大学 鎖状乳酸オリゴマー誘導体およびその製造方法
JP2005126361A (ja) * 2003-10-23 2005-05-19 Tendou Seiyaku Kk ポリ乳酸混合物を含むマトリックスメタロプロテアーゼ抑制剤
CN1562049A (zh) * 2004-04-02 2005-01-12 聂四平 低聚果糖在制备治疗及预防阴道炎药中的应用
US20050271726A1 (en) * 2004-06-02 2005-12-08 Albert Crum Immune enhancing compositions and methods of use thereof
SE528337C2 (sv) 2004-06-23 2006-10-24 Nestor Medical Ab Sammansättning innefattande mjölksyra och laktoferrin, eller ett peptidfragment därav, och användning av denna sammansättning för behandling av tillstånd i urogenitalsystemet
JP2006232909A (ja) * 2005-02-23 2006-09-07 Tokai Univ 環状オリゴ乳酸
JP4431102B2 (ja) 2005-11-11 2010-03-10 キャタピラージャパン株式会社 カウンタウエイト及びカウンタウエイトの製造方法並びに作業機械
RU2308970C1 (ru) * 2006-03-10 2007-10-27 Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") Антибактериальное средство для лечения внутриклеточных инфекций
JP2007258526A (ja) 2006-03-24 2007-10-04 Konica Minolta Holdings Inc 有機エレクトロルミネッセンス素子、及び有機エレクトロルミネッセンスディスプレイ
JP2008157576A (ja) 2006-12-26 2008-07-10 Sharp Corp 加湿機
RU2459620C2 (ru) 2007-03-30 2012-08-27 Лаккуре Аб Применение олигомеров молочной кислоты в лечении гинекологических расстройств

Also Published As

Publication number Publication date
KR101518014B1 (ko) 2015-05-06
US8425894B2 (en) 2013-04-23
MX2009010445A (es) 2010-01-29
JP2010523480A (ja) 2010-07-15
US9315444B2 (en) 2016-04-19
PL2142186T3 (pl) 2014-09-30
AU2008234064A1 (en) 2008-10-09
PT2142186E (pt) 2014-07-17
EP2142186B1 (en) 2014-04-30
CN103830216A (zh) 2014-06-04
HRP20140559T1 (hr) 2014-08-01
CN101677980B (zh) 2013-10-23
CY1115310T1 (el) 2017-01-04
KR20100016060A (ko) 2010-02-12
JP5793542B2 (ja) 2015-10-14
ZA200907215B (en) 2014-03-26
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DK2142186T3 (da) 2014-08-04
BRPI0809330B1 (pt) 2019-12-17
RU2009140141A (ru) 2011-05-10
CN103830216B (zh) 2016-08-17
CA2681803C (en) 2014-08-05
EP2142186A1 (en) 2010-01-13
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JP2014012675A (ja) 2014-01-23
US20130317104A1 (en) 2013-11-28
CN101677980A (zh) 2010-03-24
WO2008119518A1 (en) 2008-10-09
US20110020265A1 (en) 2011-01-27
CA2681803A1 (en) 2008-10-09
RU2459620C2 (ru) 2012-08-27
BRPI0809330A2 (pt) 2014-09-09
AU2008234064B2 (en) 2013-02-07
JP5409596B2 (ja) 2014-02-05
US20150025142A1 (en) 2015-01-22
SI2142186T1 (sl) 2014-08-29
US8912232B2 (en) 2014-12-16

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