BRPI0708251A2 - compostos orgánicos - Google Patents

Info

Publication number

BRPI0708251A2

BRPI0708251A2 BRPI0708251-7A BRPI0708251A BRPI0708251A2 BR PI0708251 A2 BRPI0708251 A2 BR PI0708251A2 BR PI0708251 A BRPI0708251 A BR PI0708251A BR PI0708251 A2 BRPI0708251 A2 BR PI0708251A2

Authority

BR

Brazil

Prior art keywords

formula

compound

aza

benzo

ylidene

Prior art date

2006-02-23

Links

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• 150000002894 organic compounds Chemical class 0.000 title abstract description 3
• 150000001875 compounds Chemical class 0.000 claims abstract description 178
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• 206010061218 Inflammation Diseases 0.000 claims abstract description 16
• -1 alkyl C1-C6 alkoxy Chemical group 0.000 claims description 59
• 150000003839 salts Chemical class 0.000 claims description 36
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• 239000002253 acid Substances 0.000 claims description 15
• 150000002367 halogens Chemical class 0.000 claims description 15
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 14
• 229910052736 halogen Inorganic materials 0.000 claims description 14
• 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 13
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• 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims description 9
• 125000004432 carbon atom Chemical group C* 0.000 claims description 9
• 239000000969 carrier Substances 0.000 claims description 8
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• 230000003110 anti-inflammatory effect Effects 0.000 claims description 7
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
• 229910052757 nitrogen Inorganic materials 0.000 claims description 7
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• 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims description 6
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• 125000001424 substituent group Chemical group 0.000 claims description 6
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• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 2
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• ASEWOQKMDZAFII-UHFFFAOYSA-N 2-(2,7-difluoro-4-methoxythieno[3,2-c][1]benzazepin-10-ylidene)acetic acid Chemical compound COC1=NC2=CC(F)=CC=C2C(=CC(O)=O)C2=C1C=C(F)S2 ASEWOQKMDZAFII-UHFFFAOYSA-N 0.000 claims 1
• UHQGCNJXTQOKLU-UHFFFAOYSA-N 2-(2-chloro-4-methoxythieno[3,2-c][1]benzazepin-10-ylidene)acetic acid Chemical compound COC1=NC2=CC=CC=C2C(=CC(O)=O)C2=C1C=C(Cl)S2 UHQGCNJXTQOKLU-UHFFFAOYSA-N 0.000 claims 1
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