BRPI0706575B8 - uso colágeno de tipo v ou um componente antigênico do mesmo, e, método para identificar um paciente em espera de transplante de pulmão para um risco aumentado de rejeição de tecido de órgão transplantado. - Google Patents
uso colágeno de tipo v ou um componente antigênico do mesmo, e, método para identificar um paciente em espera de transplante de pulmão para um risco aumentado de rejeição de tecido de órgão transplantado.Info
- Publication number
- BRPI0706575B8 BRPI0706575B8 BRPI0706575A BRPI0706575A BRPI0706575B8 BR PI0706575 B8 BRPI0706575 B8 BR PI0706575B8 BR PI0706575 A BRPI0706575 A BR PI0706575A BR PI0706575 A BRPI0706575 A BR PI0706575A BR PI0706575 B8 BRPI0706575 B8 BR PI0706575B8
- Authority
- BR
- Brazil
- Prior art keywords
- collagen
- type
- autoimmune response
- sample
- lung
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000012432 Collagen Type V Human genes 0.000 title abstract 3
- 108010022514 Collagen Type V Proteins 0.000 title abstract 3
- 210000000056 organ Anatomy 0.000 title abstract 3
- 210000004072 lung Anatomy 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title 1
- 238000002054 transplantation Methods 0.000 title 1
- 208000019693 Lung disease Diseases 0.000 abstract 5
- 230000006472 autoimmune response Effects 0.000 abstract 5
- 102000008186 Collagen Human genes 0.000 abstract 4
- 108010035532 Collagen Proteins 0.000 abstract 4
- 229920001436 collagen Polymers 0.000 abstract 4
- 210000001519 tissue Anatomy 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012530 fluid Substances 0.000 abstract 2
- 241000486679 Antitype Species 0.000 abstract 1
- 201000009794 Idiopathic Pulmonary Fibrosis Diseases 0.000 abstract 1
- 206010029888 Obliterative bronchiolitis Diseases 0.000 abstract 1
- 230000003367 anti-collagen effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 201000003848 bronchiolitis obliterans Diseases 0.000 abstract 1
- 208000023367 bronchiolitis obliterans with obstructive pulmonary disease Diseases 0.000 abstract 1
- 210000002808 connective tissue Anatomy 0.000 abstract 1
- 208000036971 interstitial lung disease 2 Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/12—Pulmonary diseases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Rehabilitation Therapy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75919506P | 2006-01-13 | 2006-01-13 | |
| US60/759195 | 2006-01-13 | ||
| PCT/US2007/060533 WO2007120947A1 (en) | 2006-01-13 | 2007-01-13 | Molecules for the treatment of lung disease involving an immune reaction to connective tissue found in the lung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0706575A2 BRPI0706575A2 (pt) | 2011-04-05 |
| BRPI0706575B1 BRPI0706575B1 (pt) | 2018-12-11 |
| BRPI0706575B8 true BRPI0706575B8 (pt) | 2021-05-25 |
Family
ID=38609836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0706575A BRPI0706575B8 (pt) | 2006-01-13 | 2007-01-13 | uso colágeno de tipo v ou um componente antigênico do mesmo, e, método para identificar um paciente em espera de transplante de pulmão para um risco aumentado de rejeição de tecido de órgão transplantado. |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7759075B2 (enExample) |
| EP (2) | EP1977234B1 (enExample) |
| JP (2) | JP5030973B2 (enExample) |
| CN (1) | CN101375157B (enExample) |
| AU (1) | AU2007238533C1 (enExample) |
| BR (1) | BRPI0706575B8 (enExample) |
| CA (2) | CA2641318C (enExample) |
| WO (1) | WO2007120947A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1977234B1 (en) * | 2006-01-13 | 2015-11-04 | Indiana University Research & Technology Corporation | Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis |
| EP2120967B1 (en) * | 2006-11-28 | 2015-10-21 | University Of Southern California | Method for promoting wound healing |
| JP2012518001A (ja) * | 2009-02-13 | 2012-08-09 | インディアナ ユニバーシティ リサーチ アンド テクノロジー コーポレイション | Mmp2およびmmp9を阻害する化合物および方法 |
| KR101815716B1 (ko) * | 2009-04-22 | 2018-01-05 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 | 만성 폐쇄성 폐 질환 및 천식의 치료에 사용하기 위한 조성물 |
| GB2488289A (en) | 2009-11-06 | 2012-08-22 | Univ Leland Stanford Junior | Non-invasive diagnosis of graft rejection in organ transplant patients |
| CA2856798A1 (en) * | 2011-05-31 | 2012-12-06 | Idexx Laboratories, Inc. | Detection of degradation products of feline nt-probnp |
| RU2014139546A (ru) * | 2012-03-27 | 2016-05-20 | Дженентек, Инк. | Методы прогнозирования, диагностики и лечения идиопатического легочного фиброза |
| JP6058354B2 (ja) * | 2012-11-02 | 2017-01-11 | 東芝メディカルシステムズ株式会社 | 画像処理装置及び画像処理方法 |
| JP6312054B2 (ja) * | 2013-11-06 | 2018-04-18 | 学校法人日本大学 | 間質性肺炎のバイオマーカー |
| US20170082619A1 (en) | 2015-09-23 | 2017-03-23 | One Lambda, Inc. | Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| EP0487289B1 (en) | 1990-11-20 | 1996-09-04 | BEHRINGWERKE Aktiengesellschaft | Cyclosporin immunoassay |
| US6911220B1 (en) | 1992-02-19 | 2005-06-28 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
| JP2702354B2 (ja) * | 1992-05-11 | 1998-01-21 | 帝人株式会社 | 血中の肺組織障害マーカー |
| US5778875A (en) * | 1996-05-06 | 1998-07-14 | U.S. Divers Co., Inc. | First stage regulator and rotatable in-line valve |
| AUPO026596A0 (en) * | 1996-06-05 | 1996-06-27 | Biomolecular Research Institute Limited | Viral peptide |
| US5962025A (en) | 1996-07-16 | 1999-10-05 | The University Of Tennessee Research Corporation | Method for treatment of systemic sclerosis and related fibrotic diseases |
| US5990274A (en) | 1997-11-25 | 1999-11-23 | Dade Behring Inc. | Cyclosporine derivatives and uses thereof |
| UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
| AU2001230531A1 (en) * | 2000-01-31 | 2001-08-14 | Asahi Kasei Kabushiki Kaisha | Antibody for detecting chlamydia pneumoniae |
| US7348005B2 (en) | 2000-03-15 | 2008-03-25 | Advanced Research And Technology Institute | Oral tolerance induction by collagen to prevent allograft rejection |
| BR0109455A (pt) * | 2000-03-23 | 2003-06-03 | Akzo Nobel Nv | Uso de mia e/ou seus fragmentos, método para tratar mamìferos sofrendo de, ou susceptìvel a, uma doença inflamatória, peptìdeo, composição farmacêutica, e, uso dos peptìdeos |
| JP2002220343A (ja) * | 2001-01-26 | 2002-08-09 | Toray Ind Inc | びまん性肺疾患延命剤 |
| US20050227297A1 (en) * | 2004-04-08 | 2005-10-13 | D Andrea Michael R | Method for immunohistochemical detection of collagen in a tissue sample |
| KR20080073747A (ko) | 2005-11-16 | 2008-08-11 | 유니버시티 오브 테네시 리서치 파운데이션 | 면역내성의 유도에 의한 섬유화 질환의 치료방법 |
| EP1977234B1 (en) * | 2006-01-13 | 2015-11-04 | Indiana University Research & Technology Corporation | Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis |
-
2007
- 2007-01-13 EP EP07756361.7A patent/EP1977234B1/en not_active Not-in-force
- 2007-01-13 EP EP13175642.1A patent/EP2672266B1/en not_active Not-in-force
- 2007-01-13 CA CA2641318A patent/CA2641318C/en active Active
- 2007-01-13 CN CN200780003133.2A patent/CN101375157B/zh not_active Expired - Fee Related
- 2007-01-13 BR BRPI0706575A patent/BRPI0706575B8/pt not_active IP Right Cessation
- 2007-01-13 AU AU2007238533A patent/AU2007238533C1/en not_active Ceased
- 2007-01-13 CA CA2965211A patent/CA2965211C/en active Active
- 2007-01-13 JP JP2008550549A patent/JP5030973B2/ja not_active Expired - Fee Related
- 2007-01-13 WO PCT/US2007/060533 patent/WO2007120947A1/en not_active Ceased
-
2008
- 2008-07-11 US US12/171,661 patent/US7759075B2/en active Active
-
2010
- 2010-06-25 US US12/823,570 patent/US7939281B2/en active Active
-
2011
- 2011-04-07 US US13/082,203 patent/US8039225B2/en active Active
- 2011-12-27 JP JP2011285617A patent/JP5936349B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8039225B2 (en) | 2011-10-18 |
| EP2672266A3 (en) | 2014-02-05 |
| CA2965211C (en) | 2020-06-30 |
| EP2672266A2 (en) | 2013-12-11 |
| AU2007238533B2 (en) | 2012-09-20 |
| JP5030973B2 (ja) | 2012-09-19 |
| CN101375157B (zh) | 2015-06-17 |
| CA2641318A1 (en) | 2007-10-25 |
| EP1977234A1 (en) | 2008-10-08 |
| EP1977234B1 (en) | 2015-11-04 |
| HK1126861A1 (en) | 2009-09-11 |
| JP2012108137A (ja) | 2012-06-07 |
| CA2965211A1 (en) | 2007-10-25 |
| US20110183356A1 (en) | 2011-07-28 |
| US20110020838A1 (en) | 2011-01-27 |
| EP1977234A4 (en) | 2009-06-03 |
| BRPI0706575A2 (pt) | 2011-04-05 |
| AU2007238533C1 (en) | 2013-08-15 |
| BRPI0706575B1 (pt) | 2018-12-11 |
| JP5936349B2 (ja) | 2016-06-22 |
| US20090017013A1 (en) | 2009-01-15 |
| US7939281B2 (en) | 2011-05-10 |
| CN101375157A (zh) | 2009-02-25 |
| CA2641318C (en) | 2017-06-20 |
| WO2007120947A1 (en) | 2007-10-25 |
| AU2007238533A1 (en) | 2007-10-25 |
| JP2009524023A (ja) | 2009-06-25 |
| EP2672266B1 (en) | 2018-08-01 |
| US7759075B2 (en) | 2010-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0706575B8 (pt) | uso colágeno de tipo v ou um componente antigênico do mesmo, e, método para identificar um paciente em espera de transplante de pulmão para um risco aumentado de rejeição de tecido de órgão transplantado. | |
| Jaffar et al. | Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis | |
| Humblet et al. | Acute phase proteins assessment for an early selection of treatments in growing calves suffering from bronchopneumonia under field conditions | |
| BRPI0619748B8 (pt) | anticorpo monoclonal, polinucleotídeo, composição, mistura, uso de um anticorpo monoclonal ou uma parte funcional do mesmo, método para preparar uma composição farmacêutica, linhagem celular de hibridoma isolado, método de diagnóstico de uma doença ou condição associada a amilóide em um paciente, método para diagnosticar uma predisposição para uma doença ou condição, método para monitorar doença residual mínima, método para prever a responsividade de um paciente e kits de teste | |
| Ludvigsen et al. | Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals | |
| BRPI0509419A (pt) | método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio | |
| CN106164675B (zh) | 检测人类骨膜蛋白的新型测定 | |
| Wood et al. | Accelerated onset of chronic wasting disease in elk (Cervus canadensis) vaccinated with a PrPSc-specific vaccine and housed in a prion contaminated environment | |
| Lemberger et al. | Comparison of urine protein profiles in cats without urinary tract disease and cats with idiopathic cystitis, bacterial urinary tract infection, or urolithiasis | |
| Larsen et al. | Specific haptoglobin expression in bronchoalveolar lavage during differentiation of circulating fibroblast progenitor cells in mild asthma | |
| Kushima et al. | Two cases of pleuroparenchymal fibroelastosis diagnosed with transbronchial lung biopsy | |
| US20190041407A1 (en) | Devices, systems and methods for quantifying hemoglobin s concentration | |
| Ghosh et al. | The appearance of dermcidin isoform 2, a novel platelet aggregating agent in the circulation in acute myocardial infarction that inhibits insulin synthesis and the restoration by acetyl salicylic acid of its effects | |
| WO2012165926A3 (ko) | 항-atic 자가면역항체를 포함하는 간암 진단 마커 및 이의 항원을 포함하는 간암 진단용 조성물 | |
| Glinska-Suchocka et al. | Serum concentrations of PIIINP aminopeptide in dogs with liver fibrosis | |
| CN118973710A (zh) | 用于测定血液样品中的uch-l1、gfap和其他生物标志物的系统和方法 | |
| Soltani et al. | Reticular basement membrane vessels are increased in COPD bronchial mucosa by both factor VIII and collagen IV immunostaining and are hyperpermeable | |
| Bishop et al. | Reference intervals for equine fecal calprotectin and calprotectin: protein ratio and preliminary clinical evaluation in horses with colic and colitis | |
| Clarke | Exploring the Role of Extracellular Vesicles in Equine Musculoskeletal Pathologies and Associated Regenerative Therapies | |
| Bartsch et al. | A novel approach to studying infective endocarditis: Ultrasound-guided wire injury and bacterial challenge in mice | |
| US20240067717A1 (en) | Diagnosis and treatment of primary graft dysfunction following lung transplant | |
| Hvidtfeldt et al. | Bronchoscopic mucosal cryobiopsies as a method for studying airway disease | |
| JP2008107275A (ja) | アレルギー性皮膚炎の診断法 | |
| BRPI0610267B8 (pt) | métodos de detecção de um estado doentio ou de uma suscetibilidade à doença em um indivíduo mamífero, e, uso do método | |
| Ramirez-ortiz | Role of SCARF1 in Efferocytosis and Prevention of Lupus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORA |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 11/12/2018, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/01/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B15V | Prolongation of time limit allowed | ||
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2809 DE 05-11-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |