CA2641318C - Molecules for the treatment of lung disease involving an autoimmune reaction to connective tissue found in the lung - Google Patents

Molecules for the treatment of lung disease involving an autoimmune reaction to connective tissue found in the lung Download PDF

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Publication number
CA2641318C
CA2641318C CA2641318A CA2641318A CA2641318C CA 2641318 C CA2641318 C CA 2641318C CA 2641318 A CA2641318 A CA 2641318A CA 2641318 A CA2641318 A CA 2641318A CA 2641318 C CA2641318 C CA 2641318C
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Canada
Prior art keywords
collagen
col
lung
type
transplantation
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Active
Application number
CA2641318A
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English (en)
French (fr)
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CA2641318A1 (en
Inventor
David S. Wilkes
Michael J. Klemsz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University Research and Technology Corp
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Indiana University Research and Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Indiana University Research and Technology Corp filed Critical Indiana University Research and Technology Corp
Priority to CA2965211A priority Critical patent/CA2965211C/en
Publication of CA2641318A1 publication Critical patent/CA2641318A1/en
Application granted granted Critical
Publication of CA2641318C publication Critical patent/CA2641318C/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rehabilitation Therapy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA2641318A 2006-01-13 2007-01-13 Molecules for the treatment of lung disease involving an autoimmune reaction to connective tissue found in the lung Active CA2641318C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2965211A CA2965211C (en) 2006-01-13 2007-01-13 Type v collagen-related molecules for the treatment of lung disease involving autoimmunity to type v collagen _________________________________________

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75919506P 2006-01-13 2006-01-13
US60/759,195 2006-01-13
PCT/US2007/060533 WO2007120947A1 (en) 2006-01-13 2007-01-13 Molecules for the treatment of lung disease involving an immune reaction to connective tissue found in the lung

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2965211A Division CA2965211C (en) 2006-01-13 2007-01-13 Type v collagen-related molecules for the treatment of lung disease involving autoimmunity to type v collagen _________________________________________

Publications (2)

Publication Number Publication Date
CA2641318A1 CA2641318A1 (en) 2007-10-25
CA2641318C true CA2641318C (en) 2017-06-20

Family

ID=38609836

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2641318A Active CA2641318C (en) 2006-01-13 2007-01-13 Molecules for the treatment of lung disease involving an autoimmune reaction to connective tissue found in the lung
CA2965211A Active CA2965211C (en) 2006-01-13 2007-01-13 Type v collagen-related molecules for the treatment of lung disease involving autoimmunity to type v collagen _________________________________________

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2965211A Active CA2965211C (en) 2006-01-13 2007-01-13 Type v collagen-related molecules for the treatment of lung disease involving autoimmunity to type v collagen _________________________________________

Country Status (8)

Country Link
US (3) US7759075B2 (enExample)
EP (2) EP1977234B1 (enExample)
JP (2) JP5030973B2 (enExample)
CN (1) CN101375157B (enExample)
AU (1) AU2007238533C1 (enExample)
BR (1) BRPI0706575B8 (enExample)
CA (2) CA2641318C (enExample)
WO (1) WO2007120947A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1977234B1 (en) * 2006-01-13 2015-11-04 Indiana University Research & Technology Corporation Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis
EP2120967B1 (en) * 2006-11-28 2015-10-21 University Of Southern California Method for promoting wound healing
JP2012518001A (ja) * 2009-02-13 2012-08-09 インディアナ ユニバーシティ リサーチ アンド テクノロジー コーポレイション Mmp2およびmmp9を阻害する化合物および方法
KR101815716B1 (ko) * 2009-04-22 2018-01-05 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 만성 폐쇄성 폐 질환 및 천식의 치료에 사용하기 위한 조성물
GB2488289A (en) 2009-11-06 2012-08-22 Univ Leland Stanford Junior Non-invasive diagnosis of graft rejection in organ transplant patients
CA2856798A1 (en) * 2011-05-31 2012-12-06 Idexx Laboratories, Inc. Detection of degradation products of feline nt-probnp
RU2014139546A (ru) * 2012-03-27 2016-05-20 Дженентек, Инк. Методы прогнозирования, диагностики и лечения идиопатического легочного фиброза
JP6058354B2 (ja) * 2012-11-02 2017-01-11 東芝メディカルシステムズ株式会社 画像処理装置及び画像処理方法
JP6312054B2 (ja) * 2013-11-06 2018-04-18 学校法人日本大学 間質性肺炎のバイオマーカー
US20170082619A1 (en) 2015-09-23 2017-03-23 One Lambda, Inc. Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
EP0487289B1 (en) 1990-11-20 1996-09-04 BEHRINGWERKE Aktiengesellschaft Cyclosporin immunoassay
US6911220B1 (en) 1992-02-19 2005-06-28 The General Hospital Corporation Allogeneic and xenogeneic transplantation
JP2702354B2 (ja) * 1992-05-11 1998-01-21 帝人株式会社 血中の肺組織障害マーカー
US5778875A (en) * 1996-05-06 1998-07-14 U.S. Divers Co., Inc. First stage regulator and rotatable in-line valve
AUPO026596A0 (en) * 1996-06-05 1996-06-27 Biomolecular Research Institute Limited Viral peptide
US5962025A (en) 1996-07-16 1999-10-05 The University Of Tennessee Research Corporation Method for treatment of systemic sclerosis and related fibrotic diseases
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
UA74141C2 (uk) * 1998-12-09 2005-11-15 Дж.Д. Сірл Енд Ко. Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти)
AU2001230531A1 (en) * 2000-01-31 2001-08-14 Asahi Kasei Kabushiki Kaisha Antibody for detecting chlamydia pneumoniae
US7348005B2 (en) 2000-03-15 2008-03-25 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection
BR0109455A (pt) * 2000-03-23 2003-06-03 Akzo Nobel Nv Uso de mia e/ou seus fragmentos, método para tratar mamìferos sofrendo de, ou susceptìvel a, uma doença inflamatória, peptìdeo, composição farmacêutica, e, uso dos peptìdeos
JP2002220343A (ja) * 2001-01-26 2002-08-09 Toray Ind Inc びまん性肺疾患延命剤
US20050227297A1 (en) * 2004-04-08 2005-10-13 D Andrea Michael R Method for immunohistochemical detection of collagen in a tissue sample
KR20080073747A (ko) 2005-11-16 2008-08-11 유니버시티 오브 테네시 리서치 파운데이션 면역내성의 유도에 의한 섬유화 질환의 치료방법
EP1977234B1 (en) * 2006-01-13 2015-11-04 Indiana University Research & Technology Corporation Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis

Also Published As

Publication number Publication date
US8039225B2 (en) 2011-10-18
EP2672266A3 (en) 2014-02-05
CA2965211C (en) 2020-06-30
EP2672266A2 (en) 2013-12-11
AU2007238533B2 (en) 2012-09-20
JP5030973B2 (ja) 2012-09-19
CN101375157B (zh) 2015-06-17
CA2641318A1 (en) 2007-10-25
EP1977234A1 (en) 2008-10-08
EP1977234B1 (en) 2015-11-04
HK1126861A1 (en) 2009-09-11
JP2012108137A (ja) 2012-06-07
CA2965211A1 (en) 2007-10-25
US20110183356A1 (en) 2011-07-28
BRPI0706575B8 (pt) 2021-05-25
US20110020838A1 (en) 2011-01-27
EP1977234A4 (en) 2009-06-03
BRPI0706575A2 (pt) 2011-04-05
AU2007238533C1 (en) 2013-08-15
BRPI0706575B1 (pt) 2018-12-11
JP5936349B2 (ja) 2016-06-22
US20090017013A1 (en) 2009-01-15
US7939281B2 (en) 2011-05-10
CN101375157A (zh) 2009-02-25
WO2007120947A1 (en) 2007-10-25
AU2007238533A1 (en) 2007-10-25
JP2009524023A (ja) 2009-06-25
EP2672266B1 (en) 2018-08-01
US7759075B2 (en) 2010-07-20

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