CN101375157B - 用于治疗涉及对肺中存在的结缔组织自身免疫反应的肺病的分子 - Google Patents

用于治疗涉及对肺中存在的结缔组织自身免疫反应的肺病的分子 Download PDF

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Publication number
CN101375157B
CN101375157B CN200780003133.2A CN200780003133A CN101375157B CN 101375157 B CN101375157 B CN 101375157B CN 200780003133 A CN200780003133 A CN 200780003133A CN 101375157 B CN101375157 B CN 101375157B
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col
lung
collagen
transplantation
allograft
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Chinese (zh)
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CN101375157A (zh
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D·S·威尔克斯
M·J·克莱门兹
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Indiana University Research and Technology Corp
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Indiana University Research and Technology Corp
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rehabilitation Therapy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CN200780003133.2A 2006-01-13 2007-01-13 用于治疗涉及对肺中存在的结缔组织自身免疫反应的肺病的分子 Expired - Fee Related CN101375157B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75919506P 2006-01-13 2006-01-13
US60/759,195 2006-01-13
PCT/US2007/060533 WO2007120947A1 (en) 2006-01-13 2007-01-13 Molecules for the treatment of lung disease involving an immune reaction to connective tissue found in the lung

Publications (2)

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CN101375157A CN101375157A (zh) 2009-02-25
CN101375157B true CN101375157B (zh) 2015-06-17

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CN200780003133.2A Expired - Fee Related CN101375157B (zh) 2006-01-13 2007-01-13 用于治疗涉及对肺中存在的结缔组织自身免疫反应的肺病的分子

Country Status (8)

Country Link
US (3) US7759075B2 (enExample)
EP (2) EP1977234B1 (enExample)
JP (2) JP5030973B2 (enExample)
CN (1) CN101375157B (enExample)
AU (1) AU2007238533C1 (enExample)
BR (1) BRPI0706575B8 (enExample)
CA (2) CA2641318C (enExample)
WO (1) WO2007120947A1 (enExample)

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EP1977234B1 (en) * 2006-01-13 2015-11-04 Indiana University Research & Technology Corporation Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis
EP2120967B1 (en) * 2006-11-28 2015-10-21 University Of Southern California Method for promoting wound healing
JP2012518001A (ja) * 2009-02-13 2012-08-09 インディアナ ユニバーシティ リサーチ アンド テクノロジー コーポレイション Mmp2およびmmp9を阻害する化合物および方法
KR101815716B1 (ko) * 2009-04-22 2018-01-05 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 만성 폐쇄성 폐 질환 및 천식의 치료에 사용하기 위한 조성물
GB2488289A (en) 2009-11-06 2012-08-22 Univ Leland Stanford Junior Non-invasive diagnosis of graft rejection in organ transplant patients
CA2856798A1 (en) * 2011-05-31 2012-12-06 Idexx Laboratories, Inc. Detection of degradation products of feline nt-probnp
RU2014139546A (ru) * 2012-03-27 2016-05-20 Дженентек, Инк. Методы прогнозирования, диагностики и лечения идиопатического легочного фиброза
JP6058354B2 (ja) * 2012-11-02 2017-01-11 東芝メディカルシステムズ株式会社 画像処理装置及び画像処理方法
JP6312054B2 (ja) * 2013-11-06 2018-04-18 学校法人日本大学 間質性肺炎のバイオマーカー
US20170082619A1 (en) 2015-09-23 2017-03-23 One Lambda, Inc. Methods of Detecting Alloantibodies Using HLA and Non-HLA Antigens

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
CN1227565A (zh) * 1996-06-05 1999-09-01 生物分子研究所有限公司 结构与呼吸道合胞体病毒的g蛋白同源的病毒肽
CN1406248A (zh) * 2000-01-31 2003-03-26 旭化成株式会社 肺炎衣原体检测用抗体

Family Cites Families (13)

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EP0487289B1 (en) 1990-11-20 1996-09-04 BEHRINGWERKE Aktiengesellschaft Cyclosporin immunoassay
US6911220B1 (en) 1992-02-19 2005-06-28 The General Hospital Corporation Allogeneic and xenogeneic transplantation
JP2702354B2 (ja) * 1992-05-11 1998-01-21 帝人株式会社 血中の肺組織障害マーカー
US5778875A (en) * 1996-05-06 1998-07-14 U.S. Divers Co., Inc. First stage regulator and rotatable in-line valve
US5962025A (en) 1996-07-16 1999-10-05 The University Of Tennessee Research Corporation Method for treatment of systemic sclerosis and related fibrotic diseases
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
UA74141C2 (uk) * 1998-12-09 2005-11-15 Дж.Д. Сірл Енд Ко. Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти)
US7348005B2 (en) 2000-03-15 2008-03-25 Advanced Research And Technology Institute Oral tolerance induction by collagen to prevent allograft rejection
BR0109455A (pt) * 2000-03-23 2003-06-03 Akzo Nobel Nv Uso de mia e/ou seus fragmentos, método para tratar mamìferos sofrendo de, ou susceptìvel a, uma doença inflamatória, peptìdeo, composição farmacêutica, e, uso dos peptìdeos
JP2002220343A (ja) * 2001-01-26 2002-08-09 Toray Ind Inc びまん性肺疾患延命剤
US20050227297A1 (en) * 2004-04-08 2005-10-13 D Andrea Michael R Method for immunohistochemical detection of collagen in a tissue sample
KR20080073747A (ko) 2005-11-16 2008-08-11 유니버시티 오브 테네시 리서치 파운데이션 면역내성의 유도에 의한 섬유화 질환의 치료방법
EP1977234B1 (en) * 2006-01-13 2015-11-04 Indiana University Research & Technology Corporation Type V collagen for use in a method of treatment of idiopathic pulmonary fibrosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
CN1227565A (zh) * 1996-06-05 1999-09-01 生物分子研究所有限公司 结构与呼吸道合胞体病毒的g蛋白同源的病毒肽
CN1406248A (zh) * 2000-01-31 2003-03-26 旭化成株式会社 肺炎衣原体检测用抗体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
felix fernandez-madrid et al..Autoimmunity to collagen in human lung cancer.《cancer research》.1996,第56卷第121页-第126页. *

Also Published As

Publication number Publication date
US8039225B2 (en) 2011-10-18
EP2672266A3 (en) 2014-02-05
CA2965211C (en) 2020-06-30
EP2672266A2 (en) 2013-12-11
AU2007238533B2 (en) 2012-09-20
JP5030973B2 (ja) 2012-09-19
CA2641318A1 (en) 2007-10-25
EP1977234A1 (en) 2008-10-08
EP1977234B1 (en) 2015-11-04
HK1126861A1 (en) 2009-09-11
JP2012108137A (ja) 2012-06-07
CA2965211A1 (en) 2007-10-25
US20110183356A1 (en) 2011-07-28
BRPI0706575B8 (pt) 2021-05-25
US20110020838A1 (en) 2011-01-27
EP1977234A4 (en) 2009-06-03
BRPI0706575A2 (pt) 2011-04-05
AU2007238533C1 (en) 2013-08-15
BRPI0706575B1 (pt) 2018-12-11
JP5936349B2 (ja) 2016-06-22
US20090017013A1 (en) 2009-01-15
US7939281B2 (en) 2011-05-10
CN101375157A (zh) 2009-02-25
CA2641318C (en) 2017-06-20
WO2007120947A1 (en) 2007-10-25
AU2007238533A1 (en) 2007-10-25
JP2009524023A (ja) 2009-06-25
EP2672266B1 (en) 2018-08-01
US7759075B2 (en) 2010-07-20

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