BRPI0509419A - método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio - Google Patents

método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio

Info

Publication number
BRPI0509419A
BRPI0509419A BRPI0509419-4A BRPI0509419A BRPI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A
Authority
BR
Brazil
Prior art keywords
antibodies
hybridoma
assay method
immunosorbent assay
immunoassay kit
Prior art date
Application number
BRPI0509419-4A
Other languages
English (en)
Inventor
Anan Chuntharapai
Yu-Ju G Meng
Kyu Hee Hong
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI0509419A publication Critical patent/BRPI0509419A/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/686Anti-idiotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70532B7 molecules, e.g. CD80, CD86
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/715Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"MéTODO DE ENSAIO IMUNOSSORVENTE LIGADO POR ENZIMAS, ANTICORPOS, HIBRIDOMA E KIT DE IMUNOENSAIO". A presença e a quantidade de anticorpo de interesse no fluxo Sangüíneo de paciente ou outra amostra biológica podem servir de ferramenta clínica ou outra analítica ou de diagnóstico importante. Métodos ELISA e kits para esses testes, bem como anticorpos antiidiotípicos e hibridomas que os produzem, são desenvolvidos para detectar níveis do anticorpo em amostras biológicas, que são, por exemplo, de modelos animais e pacientes humanos.
BRPI0509419-4A 2004-04-16 2005-04-15 método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio BRPI0509419A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56319304P 2004-04-16 2004-04-16
PCT/US2005/012881 WO2005108989A2 (en) 2004-04-16 2005-04-15 Assay for antibodies

Publications (1)

Publication Number Publication Date
BRPI0509419A true BRPI0509419A (pt) 2007-09-04

Family

ID=35320844

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509419-4A BRPI0509419A (pt) 2004-04-16 2005-04-15 método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio

Country Status (12)

Country Link
US (2) US20060099662A1 (pt)
EP (1) EP1745288A2 (pt)
KR (1) KR20070012826A (pt)
CN (1) CN1997893A (pt)
AU (1) AU2005241431A1 (pt)
BR (1) BRPI0509419A (pt)
CA (1) CA2563334A1 (pt)
IL (1) IL178509A0 (pt)
MX (1) MXPA06011824A (pt)
RU (1) RU2006145450A (pt)
WO (1) WO2005108989A2 (pt)
ZA (1) ZA200608572B (pt)

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SI2380911T1 (en) 2003-11-05 2018-07-31 Roche Glycart Ag ANTIGEN-RELATED PATIENTS WITH INCREASED ATTENTION ON THE RECEPTOR FC AND EFFECTORAL FUNCTION
AU2005285347A1 (en) * 2004-08-19 2006-03-23 Genentech, Inc. Polypeptide variants with altered effector function
JP2008527332A (ja) * 2004-12-31 2008-07-24 ジェネンテック・インコーポレーテッド 非ヒト血清中におけるヒト抗体の検出
DOP2006000029A (es) * 2005-02-07 2006-08-15 Genentech Inc Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
US20100015638A1 (en) * 2005-03-31 2010-01-21 Susumu Uchiyama Method for production of antibody directed against cell membrane surface antigen epitope and assaying method
RU2007143302A (ru) * 2005-04-22 2009-05-27 Дженентек, Инк. (Us) Способ лечения деменции или болезни альцгеймера антителами к cd20
WO2007056411A2 (en) * 2005-11-08 2007-05-18 Genentech, Inc. Method of producing pan-specific antibodies
CN101802005B (zh) * 2007-08-28 2015-09-16 艾伯维生物技术有限公司 包括关于阿达木单抗的结合蛋白质的组合物和方法
TW201014605A (en) 2008-09-16 2010-04-16 Genentech Inc Methods for treating progressive multiple sclerosis
JP5634405B2 (ja) * 2008-10-07 2014-12-03 ユィロス・パテント・アクチボラグGyros Patent AB 試料中のアナライトの検出のための半逐次アッセイ
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
CN102686237B (zh) 2009-07-28 2018-10-19 夏尔人类遗传性治疗公司 用于治疗戈谢病的组合物
AR078161A1 (es) 2009-09-11 2011-10-19 Hoffmann La Roche Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
CN102933231B (zh) 2010-02-10 2015-07-29 伊缪诺金公司 Cd20抗体及其用途
CN101936991B (zh) * 2010-08-03 2013-01-09 河北科技大学 微孔板洗板机双排吸液头
CN101912854B (zh) * 2010-08-03 2013-01-09 河北科技大学 微孔板洗板机双排加液头
MX360347B (es) 2010-08-17 2018-10-30 F Hoffmann La Roche Ag Star Anticuerpo anti-inmunoglobulina g1 humana.
WO2012149320A1 (en) 2011-04-29 2012-11-01 Bristol-Myers Squibb Company Ip-10 antibody dosage escalation regimens
US10590202B2 (en) * 2012-11-19 2020-03-17 Baliopharm Ag Recombinant bispecific antibody binding to CD20 and CD95
JP6446044B2 (ja) 2013-11-05 2018-12-26 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用
JP7402247B2 (ja) * 2019-03-08 2023-12-20 ジェネンテック, インコーポレイテッド 細胞外小胞の膜結合タンパク質を検出及び定量化するための方法
CN114935654B (zh) * 2022-05-26 2023-09-01 四川大学华西医院 检测样本cd72蛋白的试剂或诊断装置在制备检测脓毒症的试剂或试剂盒中的应用

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Also Published As

Publication number Publication date
RU2006145450A (ru) 2008-06-27
US20080176257A9 (en) 2008-07-24
ZA200608572B (en) 2008-06-25
IL178509A0 (en) 2007-02-11
EP1745288A2 (en) 2007-01-24
WO2005108989A3 (en) 2006-06-01
US20060099662A1 (en) 2006-05-11
KR20070012826A (ko) 2007-01-29
CN1997893A (zh) 2007-07-11
US20070015228A1 (en) 2007-01-18
WO2005108989A2 (en) 2005-11-17
MXPA06011824A (es) 2006-12-15
CA2563334A1 (en) 2005-11-17
AU2005241431A1 (en) 2005-11-17

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