BRPI0509419A - método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio - Google Patents
método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaioInfo
- Publication number
- BRPI0509419A BRPI0509419A BRPI0509419-4A BRPI0509419A BRPI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A BR PI0509419 A BRPI0509419 A BR PI0509419A
- Authority
- BR
- Brazil
- Prior art keywords
- antibodies
- hybridoma
- assay method
- immunosorbent assay
- immunoassay kit
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/686—Anti-idiotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
"MéTODO DE ENSAIO IMUNOSSORVENTE LIGADO POR ENZIMAS, ANTICORPOS, HIBRIDOMA E KIT DE IMUNOENSAIO". A presença e a quantidade de anticorpo de interesse no fluxo Sangüíneo de paciente ou outra amostra biológica podem servir de ferramenta clínica ou outra analítica ou de diagnóstico importante. Métodos ELISA e kits para esses testes, bem como anticorpos antiidiotípicos e hibridomas que os produzem, são desenvolvidos para detectar níveis do anticorpo em amostras biológicas, que são, por exemplo, de modelos animais e pacientes humanos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56319304P | 2004-04-16 | 2004-04-16 | |
PCT/US2005/012881 WO2005108989A2 (en) | 2004-04-16 | 2005-04-15 | Assay for antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509419A true BRPI0509419A (pt) | 2007-09-04 |
Family
ID=35320844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509419-4A BRPI0509419A (pt) | 2004-04-16 | 2005-04-15 | método de ensaio imunossorvente ligado por enzimas, anticorpos, hibridoma e kit de imunoensaio |
Country Status (12)
Country | Link |
---|---|
US (2) | US20060099662A1 (pt) |
EP (1) | EP1745288A2 (pt) |
KR (1) | KR20070012826A (pt) |
CN (1) | CN1997893A (pt) |
AU (1) | AU2005241431A1 (pt) |
BR (1) | BRPI0509419A (pt) |
CA (1) | CA2563334A1 (pt) |
IL (1) | IL178509A0 (pt) |
MX (1) | MXPA06011824A (pt) |
RU (1) | RU2006145450A (pt) |
WO (1) | WO2005108989A2 (pt) |
ZA (1) | ZA200608572B (pt) |
Families Citing this family (24)
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EP1642596A3 (en) * | 1999-05-07 | 2006-04-12 | Genentech, Inc. | Treatment of autoimmune diseases with antagonists which bind to B cell surface markers |
KR20040023565A (ko) * | 2000-09-18 | 2004-03-18 | 아이덱 파마슈티칼즈 코포레이션 | B 세포 고갈/면역조절 항체 조합을 이용한 자가면역질환의 치료를 위한 조합 요법 |
SI2380911T1 (en) | 2003-11-05 | 2018-07-31 | Roche Glycart Ag | ANTIGEN-RELATED PATIENTS WITH INCREASED ATTENTION ON THE RECEPTOR FC AND EFFECTORAL FUNCTION |
AU2005285347A1 (en) * | 2004-08-19 | 2006-03-23 | Genentech, Inc. | Polypeptide variants with altered effector function |
JP2008527332A (ja) * | 2004-12-31 | 2008-07-24 | ジェネンテック・インコーポレーテッド | 非ヒト血清中におけるヒト抗体の検出 |
DOP2006000029A (es) * | 2005-02-07 | 2006-08-15 | Genentech Inc | Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas) |
US20100015638A1 (en) * | 2005-03-31 | 2010-01-21 | Susumu Uchiyama | Method for production of antibody directed against cell membrane surface antigen epitope and assaying method |
RU2007143302A (ru) * | 2005-04-22 | 2009-05-27 | Дженентек, Инк. (Us) | Способ лечения деменции или болезни альцгеймера антителами к cd20 |
WO2007056411A2 (en) * | 2005-11-08 | 2007-05-18 | Genentech, Inc. | Method of producing pan-specific antibodies |
CN101802005B (zh) * | 2007-08-28 | 2015-09-16 | 艾伯维生物技术有限公司 | 包括关于阿达木单抗的结合蛋白质的组合物和方法 |
TW201014605A (en) | 2008-09-16 | 2010-04-16 | Genentech Inc | Methods for treating progressive multiple sclerosis |
JP5634405B2 (ja) * | 2008-10-07 | 2014-12-03 | ユィロス・パテント・アクチボラグGyros Patent AB | 試料中のアナライトの検出のための半逐次アッセイ |
WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
CN102686237B (zh) | 2009-07-28 | 2018-10-19 | 夏尔人类遗传性治疗公司 | 用于治疗戈谢病的组合物 |
AR078161A1 (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
CN102933231B (zh) | 2010-02-10 | 2015-07-29 | 伊缪诺金公司 | Cd20抗体及其用途 |
CN101936991B (zh) * | 2010-08-03 | 2013-01-09 | 河北科技大学 | 微孔板洗板机双排吸液头 |
CN101912854B (zh) * | 2010-08-03 | 2013-01-09 | 河北科技大学 | 微孔板洗板机双排加液头 |
MX360347B (es) | 2010-08-17 | 2018-10-30 | F Hoffmann La Roche Ag Star | Anticuerpo anti-inmunoglobulina g1 humana. |
WO2012149320A1 (en) | 2011-04-29 | 2012-11-01 | Bristol-Myers Squibb Company | Ip-10 antibody dosage escalation regimens |
US10590202B2 (en) * | 2012-11-19 | 2020-03-17 | Baliopharm Ag | Recombinant bispecific antibody binding to CD20 and CD95 |
JP6446044B2 (ja) | 2013-11-05 | 2018-12-26 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 結合分子の存在下で被検体の総量および/または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 |
JP7402247B2 (ja) * | 2019-03-08 | 2023-12-20 | ジェネンテック, インコーポレイテッド | 細胞外小胞の膜結合タンパク質を検出及び定量化するための方法 |
CN114935654B (zh) * | 2022-05-26 | 2023-09-01 | 四川大学华西医院 | 检测样本cd72蛋白的试剂或诊断装置在制备检测脓毒症的试剂或试剂盒中的应用 |
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US6528625B1 (en) * | 1996-10-28 | 2003-03-04 | Millennium Pharmaceuticals, Inc. | Anti-CCR5 antibodies and kits comprising same |
US6528624B1 (en) * | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
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-
2005
- 2005-04-15 CA CA002563334A patent/CA2563334A1/en not_active Abandoned
- 2005-04-15 WO PCT/US2005/012881 patent/WO2005108989A2/en active Application Filing
- 2005-04-15 US US11/106,762 patent/US20060099662A1/en not_active Abandoned
- 2005-04-15 MX MXPA06011824A patent/MXPA06011824A/es not_active Application Discontinuation
- 2005-04-15 ZA ZA200608572A patent/ZA200608572B/en unknown
- 2005-04-15 EP EP05778053A patent/EP1745288A2/en not_active Withdrawn
- 2005-04-15 KR KR1020067023946A patent/KR20070012826A/ko not_active Application Discontinuation
- 2005-04-15 RU RU2006145450/15A patent/RU2006145450A/ru not_active Application Discontinuation
- 2005-04-15 BR BRPI0509419-4A patent/BRPI0509419A/pt not_active IP Right Cessation
- 2005-04-15 AU AU2005241431A patent/AU2005241431A1/en not_active Abandoned
- 2005-04-15 CN CNA2005800194928A patent/CN1997893A/zh active Pending
-
2006
- 2006-09-26 US US11/535,422 patent/US20080176257A9/en not_active Abandoned
- 2006-10-05 IL IL178509A patent/IL178509A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
RU2006145450A (ru) | 2008-06-27 |
US20080176257A9 (en) | 2008-07-24 |
ZA200608572B (en) | 2008-06-25 |
IL178509A0 (en) | 2007-02-11 |
EP1745288A2 (en) | 2007-01-24 |
WO2005108989A3 (en) | 2006-06-01 |
US20060099662A1 (en) | 2006-05-11 |
KR20070012826A (ko) | 2007-01-29 |
CN1997893A (zh) | 2007-07-11 |
US20070015228A1 (en) | 2007-01-18 |
WO2005108989A2 (en) | 2005-11-17 |
MXPA06011824A (es) | 2006-12-15 |
CA2563334A1 (en) | 2005-11-17 |
AU2005241431A1 (en) | 2005-11-17 |
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