BRPI0617493B8 - hidroxiapatita multisubstituída e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos - Google Patents

hidroxiapatita multisubstituída e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos

Info

Publication number
BRPI0617493B8
BRPI0617493B8 BRPI0617493A BRPI0617493A BRPI0617493B8 BR PI0617493 B8 BRPI0617493 B8 BR PI0617493B8 BR PI0617493 A BRPI0617493 A BR PI0617493A BR PI0617493 A BRPI0617493 A BR PI0617493A BR PI0617493 B8 BRPI0617493 B8 BR PI0617493B8
Authority
BR
Brazil
Prior art keywords
preparation
multisubstituted
hydroxyapatite
composite
natural
Prior art date
Application number
BRPI0617493A
Other languages
English (en)
Inventor
Tampieri Anna
De Luca Claudio
Pressato Daniele
Landi Elena
Celotti Giancarlo
Sprio Simone
Original Assignee
C N R Consiglio Naz Delle Ricerche
Fin Ceram Faenza S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C N R Consiglio Naz Delle Ricerche, Fin Ceram Faenza S P A filed Critical C N R Consiglio Naz Delle Ricerche
Publication of BRPI0617493A2 publication Critical patent/BRPI0617493A2/pt
Publication of BRPI0617493B1 publication Critical patent/BRPI0617493B1/pt
Publication of BRPI0617493B8 publication Critical patent/BRPI0617493B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/322—Preparation by neutralisation of orthophosphoric acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

<b>hidroxiapatita multisubstituídá e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos<d>a presente invenção refere-se a uma hidroxiapatita multisubstituída por espécies iônicas fisiologicamente compatíveis e a seu compósito biohíbrido com um polímero natural e/ou sintético, que são úteis na preparação de um substituto ásseo biomimético para o tratamento de defeitos em tecidos ósseos. além do mais, a presente invenção refere-se a um método para sua preparação e a seus usos.
BRPI0617493A 2005-10-18 2006-10-12 hidroxiapatita multisubstituída e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos BRPI0617493B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2005A001966 2005-10-18
IT001966A ITMI20051966A1 (it) 2005-10-18 2005-10-18 Una idrossiapatite plurisostituita ed il relativo composito con un polimero naturale e-o sintetico loro preparazione e usi
PCT/IB2006/002844 WO2007045954A1 (en) 2005-10-18 2006-10-12 A plurisubstituted hydroxyapatite and the composite thereof with a natural and/or synthetic polymer, their preparation and uses thereof

Publications (3)

Publication Number Publication Date
BRPI0617493A2 BRPI0617493A2 (pt) 2011-07-26
BRPI0617493B1 BRPI0617493B1 (pt) 2018-05-02
BRPI0617493B8 true BRPI0617493B8 (pt) 2021-07-27

Family

ID=37745866

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0617493A BRPI0617493B8 (pt) 2005-10-18 2006-10-12 hidroxiapatita multisubstituída e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos

Country Status (12)

Country Link
US (1) US9327976B2 (pt)
EP (1) EP1948561B1 (pt)
JP (1) JP5524485B2 (pt)
AU (1) AU2006305677B2 (pt)
BR (1) BRPI0617493B8 (pt)
CA (1) CA2625173C (pt)
DK (1) DK1948561T3 (pt)
ES (1) ES2606466T3 (pt)
IT (1) ITMI20051966A1 (pt)
PL (1) PL1948561T3 (pt)
SI (1) SI1948561T1 (pt)
WO (1) WO2007045954A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051967A1 (it) * 2005-10-18 2007-04-19 C N R Consiglio Naz Delle Ri C Un composito a base di apatite e di un polisaccaride metodo per la sua preparazione e suoi usi
GB2448489A (en) * 2007-04-11 2008-10-22 Univ Aberdeen Substituted calcium phosphate materials
SE535536C2 (sv) * 2009-04-27 2012-09-11 Biomatcell Ab Jonsubstituerade hydroxiapatitytbeläggningar
CN102639159B (zh) * 2009-08-04 2015-04-01 皮斯洛克斯有限公司 离子取代的磷酸钙颗粒
IT1396934B1 (it) * 2009-11-25 2012-12-20 Fin Ceramica Faenza Spa Materiali bio-mimetici compositi, relativo processo di preparazione e loro uso per la realizzazione di strutture mono-, bi- o multi-strato per la rigenerazione di tessuto osseo, cartilagineo o osteocartilagineo
GB201010761D0 (en) 2010-06-25 2010-08-11 Univ Aberdeen Bone graft system
ITMI20102070A1 (it) * 2010-11-08 2012-05-09 Consiglio Nazionale Ricerche Impianti per sostituzioni ossee "load bearing" ad architettura gerarchicamente organizzata derivante dalla trasformazione di strutture vegetali
WO2015193836A1 (en) 2014-06-19 2015-12-23 Consiglio Nazionale Delle Ricerche (Cnr) Injectable apatitic cement ionically multi-substituted for regenerative vertebroplasty and kyphoplasty
CN104725673A (zh) * 2015-03-20 2015-06-24 东华大学 一种原位生成改性纳米羟基磷灰石/壳聚糖复合膜的方法
ITUB20156918A1 (it) * 2015-12-10 2017-06-10 Curasept A D S S R L Apatiti multi sostituite e loro uso nella rimineralizzazione e riduzione della sensibilita? dentale
JP6864360B2 (ja) * 2016-10-29 2021-04-28 公立大学法人奈良県立医科大学 ケイ酸ストロンチウムアパタイトおよびこれを含む細胞培養基材と生体活性インプラント
CN107865980A (zh) * 2017-10-10 2018-04-03 唐林元 一种仿生人工骨的制备方法
EP3786109A4 (en) * 2018-04-27 2022-01-19 Bioapatite, Inc. HYDROXYAPATITE
CN108529580B (zh) * 2018-05-18 2021-06-11 南京农业大学 一种富集碳酸根的羟基磷灰石、制备其的设备、制备方法和应用
JP7281796B2 (ja) * 2019-01-09 2023-05-26 国立研究開発法人日本原子力研究開発機構 炭酸基高含有炭酸アパタイト
KR102100961B1 (ko) * 2019-08-30 2020-04-14 김범수 유공충 유래의 골 이식재
CN112870450A (zh) * 2021-01-28 2021-06-01 中南大学湘雅医院 载二甲双胍人工骨材料以及制备人工骨的方法
WO2023140549A1 (ko) * 2022-01-18 2023-07-27 한국과학기술연구원 필러용 아파타이트 및 이를 포함하는 필러 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970004592B1 (ko) 1994-04-04 1997-03-29 이연제약 주식회사 자연골치환형 인공골과 그 제조방법
GB2316940A (en) * 1996-08-30 1998-03-11 Queen Mary & Westfield College Silicon-substituted hydroxyapatite
FR2772746B1 (fr) * 1997-12-23 2000-01-28 Commissariat Energie Atomique Procede de fabrication d'une ceramique apatitique, en particulier pour usage biologique
JP4638979B2 (ja) 2000-10-26 2011-02-23 宇部マテリアルズ株式会社 ケイ酸含有アパタイト
JP4790917B2 (ja) * 2001-02-23 2011-10-12 独立行政法人科学技術振興機構 人工椎体
FR2823992B1 (fr) * 2001-04-27 2003-06-20 Rhodia Chimie Sa Dispersions d'hydroxyapatite comprenant un acide amine en tant qu'agent stabilisant, et leur procede de preparation
KR100475828B1 (ko) * 2002-08-30 2005-03-10 요업기술원 산호 유래 인산칼슘계 다공체 및 그 제조방법
GB2395713A (en) 2002-11-13 2004-06-02 Univ Cambridge Tech A synthetic bone material
US6905723B2 (en) * 2003-05-30 2005-06-14 Depuy Products, Inc. Strontium-substituted apatite coating
DE10339953B3 (de) * 2003-08-27 2005-04-21 Coripharm Medizinprodukte Gmbh & Co. Kg. Implantatmaterial für den Knochen-Knorpel-Ersatz und seine Verwendung
KR101226811B1 (ko) * 2003-09-05 2013-01-28 신세스 게엠바하 섬유-강화 및/또는 증가된 유동성을 가지는 골 시멘트조성물
ITFI20040048A1 (it) * 2004-02-27 2004-05-27 Menarini Farma Ind Composti biomimetici contenenti idrossiapatiti sostituite con magnesio e carbonato e processi per ottenerli

Also Published As

Publication number Publication date
US20080262121A1 (en) 2008-10-23
WO2007045954A1 (en) 2007-04-26
CA2625173C (en) 2015-01-13
PL1948561T3 (pl) 2017-02-28
EP1948561A1 (en) 2008-07-30
ITMI20051966A1 (it) 2007-04-19
AU2006305677B2 (en) 2012-08-02
ES2606466T3 (es) 2017-03-24
AU2006305677A1 (en) 2007-04-26
BRPI0617493B1 (pt) 2018-05-02
JP2009511420A (ja) 2009-03-19
EP1948561B1 (en) 2016-09-07
JP5524485B2 (ja) 2014-06-18
DK1948561T3 (da) 2017-01-02
SI1948561T1 (sl) 2017-01-31
US9327976B2 (en) 2016-05-03
BRPI0617493A2 (pt) 2011-07-26
CA2625173A1 (en) 2007-04-26

Similar Documents

Publication Publication Date Title
BRPI0617493B8 (pt) hidroxiapatita multisubstituída e seu compósito com um polímero natural e/ou sintético, preparo e usos dos mesmos
BRPI0920261A8 (pt) Composto, composição farmacêutica, uso do composto, e, método para inibir ou modular atividade de proteína quinase em uma amostra biológica
WO2008130989A3 (en) Prosthetic implants
BR112012030537A2 (pt) marcador ósseo avançado e implantes personalizados
BR112015028482A2 (pt) implante cirúrgico que compreende uma camada que tem aberturas
BR112013002081A2 (pt) sistema para estabilização sacro-ilíaca
EP4275618A3 (en) Fenestrated implant
BRPI0506537A (pt) compostos que se ligam a membranas perturbadas e métodos de uso dos mesmos
CA2872799C (en) Porous spacers, instruments, and methods for foot and ankle fusion
DE112007003309A5 (de) Knochenimplantat sowie Set zur Herstellung von Knochenimplantaten
BRPI0906750B8 (pt) material polimérico biocompatível poroso e métodos
CL2008001171A1 (es) Composicion farmaceutica que comprende fibrinogeno, trombina y un compuesto que contiene estroncio; y su uso en el tratamiento de un hueso enfermo, dañado, deficiente o defectuoso.
BRPI1104008A8 (pt) Adição de porosidade microscópica à superfície de uma micromola para ser usada em implante médico
BR112013025048A2 (pt) sistemas de fixação de fratura tendo apoio intramedular
CL2009001076A1 (es) Nanoparticulas que comprende una sustancia formadora de particulas y una proteina; composicion que comprende dichas nanoparticulas; procedimiento para suministrar una proteina a traves de la membrana hematoencefalica; uso de la composicion para profilaxis o tratar enfermedades del sistema nervioso central.
BRPI0419111B8 (pt) parafuso de implante ósseo, processo para preparação do mesmo e uso do ácido hialurônico
WO2012068376A3 (en) Keratin compositions for treatment of bone deficiency or injury
BR112015016264A2 (pt) composições de crescimento ósseo termo-sensível
BR112017011315A2 (pt) ?cerâmica de vidro cristalizado de alta resistência que compreende wollastonita, hidroxiapatita e akermanita?.
BR112022022781A2 (pt) Uso de oligossacarídeos de leite humano em composições nutricionais para melhorar desenvolvimento ósseo e/ou resistência óssea
BRPI0714755B8 (pt) substituto salivar e receptáculo para substituto salivar
WO2011163398A3 (en) Biomimetic peptides for bone augmentation
CO6290611A2 (es) Clavo o tornillo de trasmision para asegurar una protesis al hueso y la instrumentacion y metodos asociados
BRPI0606898A2 (pt) uso de agonista de 5-ht4 na preparação de medicamentos e método útil no esvaziamento gástrico retardado
BRPI0607882A2 (pt) método e composição para tratamento de diabetes

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C01B 25/32 (2006.01), C01B 25/16 (2006.01), A61L 2

B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted
B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/10/2006, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO