BRPI0616894B8 - polipeptídeo de seda recombinante, polinucleotídeo exógeno, vetor de expressão, célula hospedeira bacteriana ou de levedura, processo para preparar um polipeptídeo de seda, produto, composição, uso e kit - Google Patents

polipeptídeo de seda recombinante, polinucleotídeo exógeno, vetor de expressão, célula hospedeira bacteriana ou de levedura, processo para preparar um polipeptídeo de seda, produto, composição, uso e kit

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Publication number
BRPI0616894B8
BRPI0616894B8 BRPI0616894A BRPI0616894A BRPI0616894B8 BR PI0616894 B8 BRPI0616894 B8 BR PI0616894B8 BR PI0616894 A BRPI0616894 A BR PI0616894A BR PI0616894 A BRPI0616894 A BR PI0616894A BR PI0616894 B8 BRPI0616894 B8 BR PI0616894B8
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BR
Brazil
Prior art keywords
silk polypeptide
bacterial
kit
preparing
composition
Prior art date
Application number
BRPI0616894A
Other languages
English (en)
Inventor
Sriskantha Alagacone
Trueman Holly
M Campbell Peter
Weisman Sarah
D Sutherland Tara
S Haritos Victoria
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Commw Scient Ind Res Org
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Publication date
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Publication of BRPI0616894A2 publication Critical patent/BRPI0616894A2/pt
Publication of BRPI0616894B1 publication Critical patent/BRPI0616894B1/pt
Publication of BRPI0616894B8 publication Critical patent/BRPI0616894B8/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43572Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from bees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Insects & Arthropods (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)

Abstract

proteínas da seda. a presente invenção provê proteínas da seda, bem como ácidos nucléicos que codificam essas proteínas. a presente invenção também provê células recombinantes e/ou organismos que sintetizam proteínas da seda. proteínas da seda da invenção podem ser utilizadas para uma variedade de finalidades como na fabricação de produtos de higiene pessoal, plásticos, artigos têxteis e produtos biomédicos.
BRPI0616894A 2005-10-05 2006-10-04 polipeptídeo de seda recombinante, polinucleotídeo exógeno, vetor de expressão, célula hospedeira bacteriana ou de levedura, processo para preparar um polipeptídeo de seda, produto, composição, uso e kit BRPI0616894B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72376605P 2005-10-05 2005-10-05
US60/723.766 2005-10-05
PCT/AU2006/001453 WO2007038837A1 (en) 2005-10-05 2006-10-04 Silk proteins

Publications (3)

Publication Number Publication Date
BRPI0616894A2 BRPI0616894A2 (pt) 2011-07-05
BRPI0616894B1 BRPI0616894B1 (pt) 2017-05-23
BRPI0616894B8 true BRPI0616894B8 (pt) 2021-07-27

Family

ID=37905912

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0616894A BRPI0616894B8 (pt) 2005-10-05 2006-10-04 polipeptídeo de seda recombinante, polinucleotídeo exógeno, vetor de expressão, célula hospedeira bacteriana ou de levedura, processo para preparar um polipeptídeo de seda, produto, composição, uso e kit

Country Status (15)

Country Link
US (4) US9409959B2 (pt)
EP (2) EP1931702B1 (pt)
JP (2) JP5748392B2 (pt)
KR (1) KR20080056255A (pt)
CN (1) CN101321777B (pt)
AU (1) AU2006299740B2 (pt)
BR (1) BRPI0616894B8 (pt)
CA (1) CA2624667C (pt)
DK (1) DK1931702T3 (pt)
ES (1) ES2403733T3 (pt)
HK (1) HK1119718A1 (pt)
NZ (1) NZ567202A (pt)
RU (1) RU2467015C2 (pt)
WO (1) WO2007038837A1 (pt)
ZA (1) ZA200803178B (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6358101A (ja) * 1986-08-29 1988-03-12 Hitachi Ltd 位置検出装置
JP5340593B2 (ja) 2004-05-14 2013-11-13 エシコン・エルエルシー 縫合方法および装置
CA2624667C (en) 2005-10-05 2018-01-09 Commonwealth Scientific And Industrial Research Organisation Silk proteins containing coiled coil region
CA2704769C (en) 2006-11-03 2016-01-12 Trustees Of Tufts College Nanopatterned biopolymer optical device and method of manufacturing the same
JP2010509593A (ja) * 2006-11-03 2010-03-25 トラスティーズ オブ タフツ カレッジ バイオポリマーセンサーおよびその製造方法
US8195021B2 (en) 2006-11-03 2012-06-05 Tufts University/Trustees Of Tufts College Biopolymer optical waveguide and method of manufacturing the same
US8915943B2 (en) 2007-04-13 2014-12-23 Ethicon, Inc. Self-retaining systems for surgical procedures
WO2009018610A1 (en) * 2007-08-06 2009-02-12 Commonwealth Scientific Industrial Research Organisation Cross-beta silk genes
ES2479290T3 (es) 2007-09-27 2014-07-23 Ethicon Llc Un sistema para cortar un elemento de retención en una sutura
WO2009070233A1 (en) * 2007-11-26 2009-06-04 Waters Technologies Corporation Internal standards and methods for use in quantitatively measuring analytes in a sample
US8916077B1 (en) 2007-12-19 2014-12-23 Ethicon, Inc. Self-retaining sutures with retainers formed from molten material
WO2009086172A2 (en) 2007-12-19 2009-07-09 Angiotech Pharmaceuticals, Inc. Self-retaining sutures with heat-contact mediated retainers
US8118834B1 (en) 2007-12-20 2012-02-21 Angiotech Pharmaceuticals, Inc. Composite self-retaining sutures and method
WO2009097556A2 (en) 2008-01-30 2009-08-06 Angiotech Pharmaceuticals, Inc. Appartaus and method for forming self-retaining sutures
BRPI0907787B8 (pt) 2008-02-21 2021-06-22 Angiotech Pharm Inc método para formar uma sutura de autorretenção e aparelho para elevar os retentores em um fio de sutura a um ângulo desejado
US8641732B1 (en) 2008-02-26 2014-02-04 Ethicon, Inc. Self-retaining suture with variable dimension filament and method
AU2009236330B2 (en) 2008-04-15 2014-11-27 Ethicon Llc Self-retaining sutures with bi-directional retainers or uni-directional retainers
ES2717373T3 (es) 2008-11-03 2019-06-20 Ethicon Llc Longitud de sutura de auto-retención y dispositivo para usar la misma
EP2451953A4 (en) * 2009-07-10 2013-07-03 Tufts College GEN-MANIPULATED SILK PROTEIN-BASED NUCLEIC ACID DELIVERY SYSTEMS
SG178870A1 (en) * 2009-08-26 2012-04-27 Commw Scient Ind Res Org Processes for producing silk dope
EP2509994B1 (en) * 2009-12-08 2018-09-26 AMSilk GmbH Silk Protein Coatings
WO2011090628A2 (en) 2009-12-29 2011-07-28 Angiotech Pharmaceuticals, Inc. Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods
BR112012028331B1 (pt) 2010-05-04 2020-04-28 Ethicon Endo Surgery Llc sutura de autorretenção
CN103068323B (zh) 2010-06-11 2015-07-22 伊西康有限责任公司 用于内窥镜式和机器人辅助式外科手术的缝合线递送工具
CN103747746B (zh) 2010-11-03 2017-05-10 伊西康有限责任公司 药物洗脱自固位缝合线及其相关方法
ES2612757T3 (es) 2010-11-09 2017-05-18 Ethicon Llc Suturas de autorretención de emergencia
RU2746457C2 (ru) 2011-03-23 2021-04-14 ЭТИКОН ЭлЭлСи Самоудерживающиеся нити с регулируемой петлей
US20130172931A1 (en) 2011-06-06 2013-07-04 Jeffrey M. Gross Methods and devices for soft palate tissue elevation procedures
BR112014011811A8 (pt) * 2011-11-16 2018-01-16 Commw Scient Ind Res Org genes de seda semelhantes a colágeno
EP2850191A4 (en) * 2012-03-26 2016-03-23 Commw Scient Ind Res Org SILK POLYPEPTIDES
WO2016029034A1 (en) 2014-08-20 2016-02-25 Silk Technologies, Ltd. Fibroin-derived protein composition
EP3221345B1 (en) * 2014-11-17 2020-12-23 Commonwealth Scientific and Industrial Research Organisation Metalloprotein compositions
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
CA2992462A1 (en) 2015-07-14 2017-01-19 Silk Therapeutics, Inc. Silk performance apparel and products and methods of preparing the same
WO2017075761A1 (en) 2015-11-03 2017-05-11 Colgate-Palmolive Company Bristle and toothbrush incorporating the same
AU2017267370B2 (en) 2016-04-08 2021-07-08 Cornell University A method to enhance wound healing using silk-derived protein
EP3496662A4 (en) 2016-08-12 2019-10-30 Silk Technologies Ltd. PROTEIN DERIVED FROM SILK FOR THE TREATMENT OF INFLAMMATION
CN110087691B (zh) 2016-10-17 2023-02-03 辉瑞公司 抗-edb抗体和抗体-药物缀合物
EP3688018A4 (en) 2017-09-27 2021-07-07 Evolved by Nature, Inc. SILK COVERED FABRICS, RELATED PRODUCTS AND PREPARATION PROCESSES
WO2020071208A1 (ja) * 2018-10-05 2020-04-09 国立大学法人広島大学 半月板再生用材料
CN110016438B (zh) * 2019-01-29 2021-04-13 西北大学 一种真菌菌株及其菌丝体的液体培养方法
US11976196B2 (en) * 2021-04-14 2024-05-07 Cambridge Crops, Inc. Silk packaging applications

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4720312U (pt) 1971-01-21 1972-11-07
DE3121241C2 (de) 1980-05-28 1984-07-19 Dainippon Ink And Chemicals, Inc., Tokio/Tokyo Verfahren zum Herstellen eines Verbundkunststoffrohres aus thermoplastischem Harz
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
JPH0723585B2 (ja) 1989-11-06 1995-03-15 信越化学工業株式会社 ウール処理剤
US5989894A (en) 1990-04-20 1999-11-23 University Of Wyoming Isolated DNA coding for spider silk protein, a replicable vector and a transformed cell containing the DNA
DE69131969T2 (de) * 1990-04-20 2000-06-15 Univ Wyoming Laramie Für Spinnenseideprotein kodierende DNS, DNS enthaltender Vektor, transformierte Zelle und Produkte davon
FR2695558B1 (fr) 1992-09-11 1994-10-21 Oreal Composition cosmétique contenant des particules solides revêtues avec un polymère amphotère.
DE69433299T2 (de) 1993-06-15 2004-09-09 E.I. Du Pont De Nemours And Co., Wilmington Rekombinante spinnerseide analoge
AU697440B2 (en) 1994-12-07 1998-10-08 Novozymes A/S Polypeptide with reduced allergenicity
US5939288A (en) 1995-06-07 1999-08-17 Iowa State University Research Foundation, Inc. Plant secretory signal peptides and nectarins
JPH11508542A (ja) 1995-06-26 1999-07-27 ハンス・シュヴァルツコプフ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディットゲゼルシャフト ヘアケア剤を少なくとも1種含有する染毛剤
US6013250A (en) 1995-06-28 2000-01-11 L'oreal S. A. Composition for treating hair against chemical and photo damage
IL123398A0 (en) * 1995-08-22 1998-09-24 Agricola Tech Inc Cloning methods for high strength spider silk proteins
US5792294A (en) 1995-11-16 1998-08-11 Otis Elevator Company Method of replacing sheave liner
US6398821B1 (en) 1996-12-23 2002-06-04 The Procter & Gamble Company Hair coloring compositions
JP3545588B2 (ja) 1997-03-24 2004-07-21 株式会社資生堂 毛髪化粧料
WO1998057676A1 (fr) 1997-06-18 1998-12-23 Japan As Represented By Director General Of National Institute Of Sericultural And Entomological Science Ministry Of Agriculture, Forestry And Fisheries Matiere de recouvrement de plaie contenant de la fibroine de soie et de la sericine de soie comme composants principaux et son procede de production
ES2296336T3 (es) 1997-06-25 2008-04-16 Novozymes A/S Polipeptido modificado.
US6284246B1 (en) 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
DE19848002A1 (de) 1998-10-17 2000-04-20 Goldschmidt Ag Th Polypeptid-Polysiloxan-Copolymere
JP2000139755A (ja) 1998-11-12 2000-05-23 Miki Tokushu Seishi Kk あぶらとり紙及びその製造方法
JP2000328460A (ja) 1999-05-24 2000-11-28 Dow Corning Toray Silicone Co Ltd 水系繊維処理剤および繊維の処理方法
EP1074617A3 (en) * 1999-07-29 2004-04-21 Research Association for Biotechnology Primers for synthesising full-length cDNA and their use
JP4570188B2 (ja) * 1999-11-24 2010-10-27 独立行政法人 日本原子力研究開発機構 絹繊維を微粉末化及び水溶化する方法
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
GB0108181D0 (en) 2001-04-02 2001-05-23 Xiros Plc Silk-based fibre
AU2002312426A1 (en) 2001-06-06 2002-12-16 University Of Wyoming Expression of spider silk proteins in higher plants
WO2003020916A2 (en) * 2001-08-29 2003-03-13 University Of Wyoming Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof
ITVR20010098A1 (it) 2001-09-11 2003-03-11 Consorzio Per Gli Studi Uni Procedimento per l'ottenimento di idrogeli di fibroina di seta.
US20050055051A1 (en) 2001-09-13 2005-03-10 Grafton R. Donald High strength suture with silk trace
US6902932B2 (en) 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
JP2005515309A (ja) 2002-01-09 2005-05-26 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー ポリペプチド繊維およびそれらの製造方法
AU2003202949A1 (en) 2002-01-11 2003-07-30 Ali Alwattari Methods and apparatus for spinning spider silk protein
JPWO2003100065A1 (ja) * 2002-05-23 2005-09-22 国立大学法人東京農工大学 絹タンパク質、及び、機能性を付与した遺伝子組換え絹様タンパク質の大量生産方法
US7516525B2 (en) 2002-06-13 2009-04-14 Texas Tech University Process for making chemical protective wipes and such wipes
JP3772207B2 (ja) 2002-06-19 2006-05-10 独立行政法人農業生物資源研究所 生分解性生体高分子材料、その製造方法、およびこの高分子材料からなる機能性素材
GB0218977D0 (en) * 2002-08-15 2002-09-25 Univ York Polypeptide
US20040132978A1 (en) 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
JP2006516202A (ja) 2002-12-30 2006-06-29 アンジオテック インターナショナル アクツィエン ゲゼルシャフト シルクステントグラフト
NO20030643A (no) 2003-02-07 2004-01-12 Hiform As Laminat og framgangsmåte for framstilling av et fiberarmert laminert motstandselement
US7060260B2 (en) 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
US7115388B2 (en) 2003-03-14 2006-10-03 National Institute Of Agrobiological Sciences Production of functional polypeptides originating from silk protein and use thereof
JP4357859B2 (ja) 2003-03-24 2009-11-04 トヨタ自動車株式会社 繊維複合樹脂品及びその製造方法
RU2236843C1 (ru) * 2003-08-05 2004-09-27 Злобин Виктор Сергеевич Лечебно-косметическое средство
DE10336509A1 (de) 2003-08-08 2005-03-03 Ledertech Gmbh Verbundmaterial für thermisch formbare Schuhkomponenten auf organischer Faserbasis
US20070082197A1 (en) 2003-11-04 2007-04-12 Ko Frank K Electrospun carbon nanotube reinforced silk fibers
US7314851B2 (en) 2003-12-11 2008-01-01 The Foundation for the Promotion of Supplementary Occupations and Related Techniques of her Majesty Queen Sirikit Silk soap comprising sericin protein
JP4815108B2 (ja) 2003-12-26 2011-11-16 イビデン株式会社 ハニカム構造体
US20050161058A1 (en) 2004-01-26 2005-07-28 Israel Yerushalmy Spider silk dental floss
CA2624667C (en) * 2005-10-05 2018-01-09 Commonwealth Scientific And Industrial Research Organisation Silk proteins containing coiled coil region

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CA2624667A1 (en) 2007-04-12
KR20080056255A (ko) 2008-06-20
US20170051025A1 (en) 2017-02-23
DK1931702T3 (da) 2013-04-15
US20100100975A1 (en) 2010-04-22
CA2624667C (en) 2018-01-09
JP2009509550A (ja) 2009-03-12
ZA200803178B (en) 2009-08-26
EP2395014A3 (en) 2012-07-11
RU2467015C2 (ru) 2012-11-20
US20120245103A1 (en) 2012-09-27
BRPI0616894B1 (pt) 2017-05-23
AU2006299740B2 (en) 2012-07-05
EP2395014A2 (en) 2011-12-14
US8481681B2 (en) 2013-07-09
CN101321777B (zh) 2015-10-21
ES2403733T3 (es) 2013-05-21
JP6339459B2 (ja) 2018-06-06
HK1119718A1 (en) 2009-03-13
US9409959B2 (en) 2016-08-09
AU2006299740A1 (en) 2007-04-12
EP1931702A1 (en) 2008-06-18
EP1931702A4 (en) 2009-01-21
JP5748392B2 (ja) 2015-07-15
BRPI0616894A2 (pt) 2011-07-05
WO2007038837A1 (en) 2007-04-12
NZ567202A (en) 2012-02-24
CN101321777A (zh) 2008-12-10
JP2015002746A (ja) 2015-01-08
RU2008117631A (ru) 2009-11-10
US20210094989A1 (en) 2021-04-01
EP1931702B1 (en) 2013-01-02

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