BRPI0516951A2 - isolados da sÍndrome respiratària e reprodutora suÍna e mÉtodos de uso - Google Patents

isolados da sÍndrome respiratària e reprodutora suÍna e mÉtodos de uso

Info

Publication number
BRPI0516951A2
BRPI0516951A2 BRPI0516951-8A BRPI0516951A BRPI0516951A2 BR PI0516951 A2 BRPI0516951 A2 BR PI0516951A2 BR PI0516951 A BRPI0516951 A BR PI0516951A BR PI0516951 A2 BRPI0516951 A2 BR PI0516951A2
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BR
Brazil
Prior art keywords
isolate
virulence
methods
isolated
swine respiratory
Prior art date
Application number
BRPI0516951-8A
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English (en)
Inventor
Michael Roof
Eric Vaughn
Wesley Johnson
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of BRPI0516951A2 publication Critical patent/BRPI0516951A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10031—Uses of virus other than therapeutic or vaccine, e.g. disinfectant
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

ISOLADOS DA SÍNDROME RESPIRATàRIA E REPRODUTORA SUÍNA E METODOS DE USO. A presente invenção refere-se a um método de predizer a virulência de um isolado de vírus PRRS novo ou descaracterizado, em que o isolado é injetado no suíno e permitido replicar por um período de cerca de 3 a 15 dias. Durante este período, a taxa de crescimento de vírus e/ou magnitude de viremia é determinada, e estes dados são comparados com a taxa de crescimento e/ou magnitude de viremia correspondentes de um isolado de vírus PRRS de virulência desconhecida, como uma medição da virulência de um isolado novo ou descaracterizado. Adicionalmente, também é provido um método de seleção de um isolado para inclusão em uma composição imunogênica, junto com composições incorporando formas atenuadas de vírus preditas como virulentas.
BRPI0516951-8A 2004-09-21 2005-09-21 isolados da sÍndrome respiratària e reprodutora suÍna e mÉtodos de uso BRPI0516951A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61182404P 2004-09-21 2004-09-21
US11/022,262 US7632636B2 (en) 2004-09-21 2004-12-23 Porcine reproductive and respiratory syndrome isolates and methods of use
PCT/US2005/033760 WO2006034319A2 (en) 2004-09-21 2005-09-21 Porcine reproductive and respiratory syndrome isolates and methods of use

Publications (1)

Publication Number Publication Date
BRPI0516951A2 true BRPI0516951A2 (pt) 2009-03-10

Family

ID=36074481

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0516951-8A BRPI0516951A2 (pt) 2004-09-21 2005-09-21 isolados da sÍndrome respiratària e reprodutora suÍna e mÉtodos de uso

Country Status (11)

Country Link
US (3) US7632636B2 (pt)
EP (3) EP2298938A1 (pt)
JP (1) JP2008513501A (pt)
KR (1) KR20070105965A (pt)
AT (1) ATE518012T1 (pt)
AU (1) AU2005286797A1 (pt)
BR (1) BRPI0516951A2 (pt)
CA (1) CA2577801A1 (pt)
MX (1) MX2007002771A (pt)
RU (1) RU2407802C2 (pt)
WO (1) WO2006034319A2 (pt)

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BRPI0510928A (pt) 2004-06-18 2007-11-13 Univ Minnesota identificação de organismos viralmente infectados e vacinados
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
UA95778C2 (ru) 2005-06-24 2011-09-12 Риджентс Оф Зе Юниверсити Оф Миннесота Вирусы репродуктивно-респираторного синдрома свиней, их инфекционные клоны и мутанты и способы применения
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
MY186535A (en) 2011-02-17 2021-07-26 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
WO2012110490A1 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of prrsv
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EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
CN103487582A (zh) * 2013-10-11 2014-01-01 重庆出入境检验检疫局检验检疫技术中心 猪繁殖与呼吸综合征病毒抗体竞争 AlphaLISA检测试剂盒及其方法
CN103499689A (zh) * 2013-10-11 2014-01-08 重庆出入境检验检疫局检验检疫技术中心 猪圆环病毒2型病毒抗体竞争 AlphaLISA检测试剂盒及检测方法
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US20100028860A1 (en) 2010-02-04
KR20070105965A (ko) 2007-10-31
WO2006034319A2 (en) 2006-03-30
RU2007114957A (ru) 2008-10-27
MX2007002771A (es) 2008-03-07
EP2298938A1 (en) 2011-03-23
AU2005286797A1 (en) 2006-03-30
US7632636B2 (en) 2009-12-15
ATE518012T1 (de) 2011-08-15
JP2008513501A (ja) 2008-05-01
EP2314721A1 (en) 2011-04-27
EP1794329A2 (en) 2007-06-13
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WO2006034319A3 (en) 2006-07-27

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