EA200501363A1 - Состав для ингалятора, выдающего мерную дозу препарата, с использованием гидрофторалканов в качестве пропеллентов - Google Patents

Состав для ингалятора, выдающего мерную дозу препарата, с использованием гидрофторалканов в качестве пропеллентов

Info

Publication number
EA200501363A1
EA200501363A1 EA200501363A EA200501363A EA200501363A1 EA 200501363 A1 EA200501363 A1 EA 200501363A1 EA 200501363 A EA200501363 A EA 200501363A EA 200501363 A EA200501363 A EA 200501363A EA 200501363 A1 EA200501363 A1 EA 200501363A1
Authority
EA
Eurasian Patent Office
Prior art keywords
inhaler
dose
mergene
hydrofluoralkanes
propellants
Prior art date
Application number
EA200501363A
Other languages
English (en)
Other versions
EA009087B1 (ru
Inventor
Джордж Дестефано
Линда Джин Келаш - Каннаво
Original Assignee
Бёрингер Ингельхайм Фармасьютиклз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Фармасьютиклз, Инк. filed Critical Бёрингер Ингельхайм Фармасьютиклз, Инк.
Publication of EA200501363A1 publication Critical patent/EA200501363A1/ru
Publication of EA009087B1 publication Critical patent/EA009087B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

В заявке описан улучшенный суспензионный состав, предназначенный для использования в ингаляторе, выдающем мерную дозу препарата, причем состав содержит гидрофторалкан в качестве пропеллента, а улучшение свойств состава достигается при добавлении контролируемого небольшого количества воды.
EA200501363A 2003-03-20 2004-03-19 Состав для ингалятора, выдающего мерную дозу препарата, с использованием гидрофторалканов в качестве пропеллентов EA009087B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45611303P 2003-03-20 2003-03-20
PCT/US2004/008375 WO2004084858A2 (en) 2003-03-20 2004-03-19 Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants

Publications (2)

Publication Number Publication Date
EA200501363A1 true EA200501363A1 (ru) 2006-04-28
EA009087B1 EA009087B1 (ru) 2007-10-26

Family

ID=33098086

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501363A EA009087B1 (ru) 2003-03-20 2004-03-19 Состав для ингалятора, выдающего мерную дозу препарата, с использованием гидрофторалканов в качестве пропеллентов

Country Status (28)

Country Link
US (1) US7914770B2 (ru)
EP (1) EP1608336B1 (ru)
JP (1) JP4708332B2 (ru)
KR (1) KR101113003B1 (ru)
CN (1) CN1761455A (ru)
AT (1) ATE390125T1 (ru)
AU (1) AU2004224367B2 (ru)
BR (1) BRPI0408547A (ru)
CA (1) CA2519523C (ru)
CO (1) CO5640070A2 (ru)
CY (1) CY1108137T1 (ru)
DE (1) DE602004012718T2 (ru)
DK (1) DK1608336T3 (ru)
EA (1) EA009087B1 (ru)
EC (1) ECSP056029A (ru)
ES (1) ES2304616T3 (ru)
HR (1) HRP20050822B1 (ru)
ME (1) ME00420B (ru)
MX (1) MXPA05009920A (ru)
NO (1) NO336457B1 (ru)
NZ (1) NZ542957A (ru)
PL (1) PL1608336T3 (ru)
PT (1) PT1608336E (ru)
RS (1) RS51663B (ru)
SI (1) SI1608336T1 (ru)
UA (1) UA89751C2 (ru)
WO (1) WO2004084858A2 (ru)
ZA (1) ZA200506463B (ru)

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NZ552869A (en) 2004-07-02 2010-06-25 Boehringer Ingelheim Int Aerosol suspension formulations containing TG 227 ea as a propellant, an ipratropium or tiotropium salt and a small amount of free water to stabilise the composition
US20060140873A1 (en) * 2004-12-27 2006-06-29 Chang Heng W Aerosol pharmaceutical compositions
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006014433A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
WO2009026178A2 (en) * 2007-08-17 2009-02-26 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
WO2010019953A1 (en) 2008-08-15 2010-02-18 Arcion Therapeutics, Inc. High concentration local anesthetic formulations for treating non-neuropathic pain
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
NZ599295A (en) 2009-11-25 2014-06-27 Boehringer Ingelheim Int Nebulizer
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN102798044B (zh) * 2012-08-02 2014-09-10 深圳市华星光电技术有限公司 侧入式背光模组
US9744313B2 (en) 2013-08-09 2017-08-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
US10195374B2 (en) 2014-05-07 2019-02-05 Boehringer Ingelheim International Gmbh Container, nebulizer and use
WO2015169430A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Nebulizer
US10716906B2 (en) 2014-05-07 2020-07-21 Boehringer Ingelheim International Gmbh Nebulizer and container
US20180071231A1 (en) * 2015-04-10 2018-03-15 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2021216779A1 (en) * 2020-04-21 2021-10-28 Amphastar Pharmaceuticals, Inc. Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery

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PL177078B1 (pl) * 1992-12-09 1999-09-30 Boehringer Ingelheim Pharma Preparaty roztworów aerozolowych
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Also Published As

Publication number Publication date
DK1608336T3 (da) 2008-06-02
AU2004224367A1 (en) 2004-10-07
PT1608336E (pt) 2008-04-21
DE602004012718T2 (de) 2009-05-07
EP1608336A2 (en) 2005-12-28
WO2004084858A3 (en) 2004-11-04
ECSP056029A (es) 2006-01-27
KR101113003B1 (ko) 2012-02-24
AU2004224367B2 (en) 2009-10-08
HRP20050822A2 (en) 2006-10-31
CO5640070A2 (es) 2006-05-31
MXPA05009920A (es) 2005-11-04
WO2004084858A2 (en) 2004-10-07
UA89751C2 (ru) 2010-03-10
SI1608336T1 (sl) 2008-08-31
ATE390125T1 (de) 2008-04-15
NO20054839L (no) 2005-10-19
RS20050705A (en) 2008-04-04
RS51663B (en) 2011-10-31
CA2519523A1 (en) 2004-10-07
KR20050111382A (ko) 2005-11-24
JP4708332B2 (ja) 2011-06-22
ZA200506463B (en) 2006-04-26
JP2006520797A (ja) 2006-09-14
US7914770B2 (en) 2011-03-29
DE602004012718D1 (de) 2008-05-08
ES2304616T3 (es) 2008-10-16
CN1761455A (zh) 2006-04-19
HRP20050822B1 (hr) 2013-09-30
ME00420B (me) 2011-12-20
BRPI0408547A (pt) 2006-03-07
US20040184994A1 (en) 2004-09-23
NZ542957A (en) 2008-09-26
EP1608336B1 (en) 2008-03-26
NO336457B1 (no) 2015-08-31
CA2519523C (en) 2012-03-13
EA009087B1 (ru) 2007-10-26
PL1608336T3 (pl) 2008-09-30
CY1108137T1 (el) 2014-02-12

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