BRPI0515289B8 - dispositivos de liberação nasal - Google Patents

dispositivos de liberação nasal

Info

Publication number
BRPI0515289B8
BRPI0515289B8 BRPI0515289A BRPI0515289A BRPI0515289B8 BR PI0515289 B8 BRPI0515289 B8 BR PI0515289B8 BR PI0515289 A BRPI0515289 A BR PI0515289A BR PI0515289 A BRPI0515289 A BR PI0515289A BR PI0515289 B8 BRPI0515289 B8 BR PI0515289B8
Authority
BR
Brazil
Prior art keywords
container
subject
substance
container chamber
mouthpiece
Prior art date
Application number
BRPI0515289A
Other languages
English (en)
Inventor
David Sheldrake Colin
Gisle Djupesland Per
Peter Hafner Roderick
Original Assignee
Optinose As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optinose As filed Critical Optinose As
Publication of BRPI0515289A publication Critical patent/BRPI0515289A/pt
Publication of BRPI0515289B1 publication Critical patent/BRPI0515289B1/pt
Publication of BRPI0515289B8 publication Critical patent/BRPI0515289B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • A61M15/0098Activated by exhalation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/105Filters
    • A61M16/1055Filters bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/105Filters
    • A61M16/106Filters in a path
    • A61M16/1065Filters in a path in the expiratory path
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1075Preparation of respiratory gases or vapours by influencing the temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Massaging Devices (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

dispositivos de liberação nasal um dispositivo de liberação nasal e método de liberação de substância a uma cavidade nasal de um sujeito, o dispositivo de liberação compreendendo: uma unidade de recebimento de recipiente compreendendo uma câmara de recipiente para receber um recipiente contendo substância que contém substância a ser liberada à cavidade nasal do sujeito, a câmara de recipiente incluindo uma entrada e uma saída; uma unidade de peça que se adapta ao nariz incluindo uma peça que se adapta ao nariz para se ajustar a uma cavidade nasal do sujeito e estando em comunicação de fluido com a saída da câmara de recipiente; uma unidade de boquim incluindo um boquim em comunicação de fluido com a entrada da câmara de recipiente e através da qual o sujeito em uso exala, tal como para inserir substância a partir do recipiente e liberar a mesma através da peça que se adapta ao nariz; e dispositivo de suavização de umidade para suavizar um efeito de umidade em uma respiração exalada na entrada de substância a partir do recipiente, que dispositivos são fornecidos, por exemplo, através de fornecer o recipiente em um membro contendo recipiente substituível, através de uma válvula sensível a pressão que normalmente fecha a conexão de fluido entre a câmara de recipiente e a boquim, e um regulador de temperatura fluxo acima da câmara de recipiente.
BRPI0515289A 2004-09-15 2005-09-15 dispositivos de liberação nasal BRPI0515289B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0420513A GB0420513D0 (en) 2004-09-15 2004-09-15 Powder delivery devices
GB0420513.4 2004-09-15
PCT/GB2005/003549 WO2006030210A2 (en) 2004-09-15 2005-09-15 Nasal delivery devices

Publications (3)

Publication Number Publication Date
BRPI0515289A BRPI0515289A (pt) 2008-07-15
BRPI0515289B1 BRPI0515289B1 (pt) 2017-10-10
BRPI0515289B8 true BRPI0515289B8 (pt) 2021-06-22

Family

ID=33306617

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0515289A BRPI0515289B8 (pt) 2004-09-15 2005-09-15 dispositivos de liberação nasal

Country Status (19)

Country Link
US (5) US20080289629A1 (pt)
EP (3) EP2462973B1 (pt)
JP (5) JP5032323B2 (pt)
KR (2) KR101324023B1 (pt)
CN (2) CN102000374B (pt)
AU (1) AU2005283922A1 (pt)
BR (1) BRPI0515289B8 (pt)
CA (3) CA2580217C (pt)
DK (2) DK2462972T3 (pt)
ES (2) ES2546934T3 (pt)
GB (4) GB0420513D0 (pt)
IL (1) IL181940A0 (pt)
IN (1) IN2014DN10605A (pt)
MX (2) MX2007003052A (pt)
NO (1) NO337577B1 (pt)
PL (2) PL1799290T3 (pt)
RU (1) RU2428217C2 (pt)
SG (1) SG155889A1 (pt)
WO (1) WO2006030210A2 (pt)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0121568D0 (en) 2001-09-06 2001-10-24 Optinose As Nasal delivery device
CA2364009C (en) * 1999-03-03 2007-02-27 Per Gisle Djupesland Nasal delivery device
GB0114272D0 (en) 2001-06-12 2001-08-01 Optinose As Nasal delivery device
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
GB0209494D0 (en) * 2002-04-25 2002-06-05 Optinose As Nasal devices
GB0215270D0 (en) 2002-07-02 2002-08-14 Optinose As Nasal devices
GB0215904D0 (en) * 2002-07-09 2002-08-21 Team Holdings Uk Ltd Drug delivery system and method
GB0311570D0 (en) 2003-05-20 2003-06-25 Optinose As Delivery device and method
GB0319119D0 (en) 2003-08-14 2003-09-17 Optinose As Delivery devices
GB0320171D0 (en) 2003-08-28 2003-10-01 Optinose As Delivery devices
GB0420513D0 (en) 2004-09-15 2004-10-20 Optinose As Powder delivery devices
GB0503738D0 (en) * 2005-02-23 2005-03-30 Optinose As Powder delivery devices
CA2642608C (en) 2006-01-19 2018-05-29 Optinose As Nasal administration
WO2007093784A1 (en) * 2006-02-14 2007-08-23 Optinose As Delivery device and method
GB0602980D0 (en) * 2006-02-14 2006-03-29 Optinose As Delivery device and method
GB0604319D0 (en) * 2006-03-03 2006-04-12 Optinose As Nasal delivery
GB0604444D0 (en) * 2006-03-06 2006-04-12 Optinose As Nasal devices
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
EP1844805A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co.KG Inhalator
GB2437488A (en) * 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
GB2438834A (en) 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
GB2440316A (en) 2006-07-25 2008-01-30 Optinose As Nasal inhaler with scrubber
GB0623728D0 (en) * 2006-11-28 2007-01-10 Optinose As Delivery devices
GB2468794B (en) * 2006-11-28 2011-07-13 Optinose As Delivery devices
GB2477225B (en) * 2006-11-28 2012-04-04 Optinose As Nasal delivery devices
GB0623732D0 (en) * 2006-11-28 2007-01-10 Optinose As Powder delivery devices
GB0623731D0 (en) * 2006-11-28 2007-01-10 Optinose As Delivery device
US8196576B2 (en) * 2007-02-28 2012-06-12 Microdose Therapeutx, Inc. Inhaler
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
GB2448193A (en) * 2007-04-05 2008-10-08 Optinose As Nasal delivery device
GB0719299D0 (en) 2007-10-03 2007-11-14 Optinose As Nasal delivery devices
CN101459908B (zh) * 2007-12-13 2012-04-25 华为技术有限公司 一种业务订阅方法、系统、服务器
WO2011013003A2 (en) 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
DE102009037840B4 (de) * 2009-08-18 2012-08-16 Gamptec Gmbh Inhalationsvorrichtung und Verfahren zur Inhalation eines Wirkstoffs aus einer Kapsel
US8746244B2 (en) * 2009-10-02 2014-06-10 Boehringer Ingelheim International Gmbh Powder inhaler
GB201015371D0 (en) 2010-09-14 2010-10-27 Optinose As Nasal delivery
AU2012212866B2 (en) * 2011-01-31 2016-09-15 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2012123819A1 (en) 2011-03-15 2012-09-20 Optinose As Et Al Nasal delivery
RU2741249C2 (ru) 2011-05-09 2021-01-22 Импел Ньюрофарма Инк. Наконечники для назальной доставки лекарственных средств
WO2013009874A1 (en) * 2011-07-13 2013-01-17 The Foundry, Llc Delivery devices for nasopharyngeal mucosa targets
MX358061B (es) 2012-02-24 2018-08-03 Optinose As Dispositivos de suministro nasal.
JP6243360B2 (ja) 2012-02-24 2017-12-06 オプティノーズ アズ 経鼻配送装置
MX358062B (es) 2012-02-24 2018-08-03 Optinose As Dispositivos de suministro nasal.
EP2858701A2 (en) * 2012-06-06 2015-04-15 AeroDesigns, Inc Aerosol dispenser with replaceable cartridge
WO2014004400A2 (en) * 2012-06-28 2014-01-03 The Governt. Of The Usa As Represented By The Secretary Of The Department Of Health & Human Services Nasal dry powder delivery system for vaccines and other treatment agents
EP2903608B1 (en) 2012-10-03 2019-08-28 Proponent Biotech GmbH Pharmaceutical composition comprising propionic acid for use in the treatment of viral infections
US9884157B2 (en) * 2013-03-15 2018-02-06 Microdose Therapeutx, Inc. Inhalation device, control method and computer program
US11554229B2 (en) 2013-03-26 2023-01-17 OptiNose Inc. Nasal administration
USD761951S1 (en) 2013-05-23 2016-07-19 Optinose As Nosepiece unit
EP2868334B1 (de) 2013-11-05 2017-01-11 Benedict Gerber Nasendusche
CN103611213A (zh) * 2013-12-16 2014-03-05 梁卓 一种鼻炎烟熏装置
CN103611207A (zh) * 2013-12-16 2014-03-05 梁卓 一种鼻炎烟熏治疗仪
AU2015348301B2 (en) * 2014-11-19 2020-09-03 Optinose, Inc. Intranasal administration
EP3349831A4 (en) * 2015-09-16 2019-06-05 1355540 Ontario Inc. SYSTEM AND METHOD FOR DRY POWDER DISPENSING
US11432993B2 (en) 2016-09-14 2022-09-06 Healthy Humming, LLC Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat
WO2018053079A1 (en) 2016-09-14 2018-03-22 Bogan Consulting Services, P.A. Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat
US11305077B2 (en) 2016-09-14 2022-04-19 Healthy Humming, LLC Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat
US11213641B2 (en) 2016-09-14 2022-01-04 Healthy Humming, LLC Therapeutic device for treatment of conditions relating to the sinuses, nasal cavities, ear, nose and throat
GB201700727D0 (en) * 2017-01-16 2017-03-01 Teva Pharma Inhalers and airflow adaptors therefor
CN111050828B (zh) 2017-09-15 2022-09-20 株式会社新日本科学 药剂保存用带喷嘴药筒及其喷射器、以及鼻腔用粉状药剂给药装置
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN109821118A (zh) * 2017-11-23 2019-05-31 正大天晴药业集团股份有限公司 新型肺部药物输送系统
KR102138725B1 (ko) * 2018-04-19 2020-07-28 조민수 구강 및 비강 내에 약액을 도포하기 위한 분무 장치
KR102140739B1 (ko) * 2018-04-23 2020-08-04 충남대학교산학협력단 상기도 분무 장치
AU2019355852A1 (en) * 2018-10-02 2021-04-01 Boston Scientific Scimed, Inc. Devices for fluidization and delivering a powdered agent
WO2020070321A2 (en) 2018-10-04 2020-04-09 Optinose As Exhalation delivery system for and method of treating sinus disease
CN109939326B (zh) * 2019-04-18 2023-10-31 首都医科大学附属北京安贞医院 基于呼气压力的嗅觉训练装置
CN111514418B (zh) * 2019-06-12 2022-01-14 中南大学湘雅二医院 一种自吸式经鼻粉末材料给送装置
US11717621B2 (en) 2019-06-24 2023-08-08 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device
US11793951B2 (en) 2019-06-24 2023-10-24 De Motu Cordis Pty Ltd Automatic dispenser for respiratory delivery device and method
US10828432B1 (en) * 2019-06-24 2020-11-10 De Motu Cordis Pty Ltd Respiratory delivery device and method
US11883582B2 (en) * 2019-10-17 2024-01-30 Astrazeneca Ab Inhaler
AU2021210405A1 (en) 2020-01-22 2022-08-25 Seelos Therapeutics, Inc. Reducing side effects of NMDA antagonists
FR3115996A1 (fr) * 2020-11-06 2022-05-13 Nemera La Verpilliere Système d’assistance à la distribution de produit
TW202310825A (zh) 2021-05-14 2023-03-16 美商西羅斯醫療公司 減少nmda受體拮抗劑之副作用
WO2022241214A1 (en) 2021-05-14 2022-11-17 Seelos Therapeutics, Inc. Methods of using nmda receptor antagonists
CN113616886B (zh) * 2021-08-19 2023-04-28 艾特申博(苏州)医药科技有限公司 一种鼻腔给药干粉递送装置
CN113546290A (zh) * 2021-08-19 2021-10-26 南京澳博工业智能科技研究院有限公司 一种鼻腔给药装置
WO2023069126A1 (en) * 2021-10-19 2023-04-27 Odyssey Health, Inc. Breath-powered nasal devices for treatment of traumatic brain injury (tbi), including concussion, and methods and methods
CN113941077A (zh) * 2021-12-21 2022-01-18 时新(上海)产品设计有限公司 高压空气胶囊及包含其的喷剂装置、喷剂组件

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US605436A (en) 1898-06-07 Inhaler
US642748A (en) 1899-02-23 1900-02-06 Arthur Manners Inhaler.
US658436A (en) 1900-05-28 1900-09-25 Hans Hennerich Groth Insufflator.
US746749A (en) 1903-03-18 1903-12-15 George E Seidel Nasal medicator.
US794641A (en) 1905-03-06 1905-07-11 Alfred H Ramey Inhaler.
US902832A (en) 1907-09-20 1908-11-03 Edward F Philbrook Inhaler.
FR2224175B1 (pt) * 1973-04-04 1978-04-14 Isf Spa
IT982765B (it) * 1973-04-13 1974-10-21 Farmaceutici Italia Apparecchio inalatore
US3888252A (en) 1974-01-23 1975-06-10 Anthony J Side Powder inhaler
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
US5038769A (en) * 1983-06-29 1991-08-13 Krauser Robert S Method and apparatus for treating ailments
US4796614A (en) * 1987-02-26 1989-01-10 Trutek Research, Inc. Collapsible inhalation valve
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
WO1992003175A1 (en) * 1990-08-11 1992-03-05 Fisons Plc Inhalation device
JP2856909B2 (ja) * 1991-04-15 1999-02-10 レイラス・オサケユキデュア 吸入用粉末状薬剤の用量を計測する装置
JPH0614973B2 (ja) 1992-03-31 1994-03-02 テクノ・バイタル工業株式会社 蒸気吸入式治療器
JPH08506504A (ja) 1993-02-12 1996-07-16 ミネソタ マイニング アンド マニュファクチャリング カンパニー エアゾール導入器具
JP3372105B2 (ja) 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP3748890B2 (ja) * 1994-10-28 2006-02-22 アラダイム コーポレーション 呼吸器薬物のエアロゾル化噴霧に使用するための使い捨て容器、使い捨てパッケージ、薬物輸送装置、及びエアロゾルを生成する方法
DE69607143T2 (de) 1995-01-23 2000-11-16 Direct Haler As Odense Inhalator
JPH08238318A (ja) * 1995-03-03 1996-09-17 Unisia Jecs Corp 鼻腔用投薬器
JP3308425B2 (ja) * 1995-03-10 2002-07-29 株式会社ユニシアジェックス 鼻腔用投薬器
JP3320261B2 (ja) 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
JP3315031B2 (ja) * 1995-11-27 2002-08-19 株式会社ユニシアジェックス 投薬器
US5797392C1 (en) 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5797390A (en) * 1996-03-06 1998-08-25 Mcsoley; Thomas E. Nasal inhaler having a directed spray pattern
AUPN976496A0 (en) 1996-05-10 1996-05-30 Glaxo Wellcome Australia Ltd Unit dose dispensing device
FR2751553B1 (fr) * 1996-07-23 1999-06-11 Pedrali Franck Procede pour l'amelioration de la diffusion d'un produit bronchodilatateur en spray et appareils le mettant en oeuvre
DE19647947A1 (de) * 1996-11-20 1998-05-28 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
SE9700424D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Powder inhaler
JP3011898B2 (ja) 1997-02-20 2000-02-21 フォルテ グロウ メディカル株式会社 吸引器
SE9701750D0 (sv) * 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
US6648848B1 (en) * 1997-05-27 2003-11-18 Direct-Haler A/S Inhaler for powdered medicaments
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
CA2364009C (en) * 1999-03-03 2007-02-27 Per Gisle Djupesland Nasal delivery device
GB9904906D0 (en) 1999-03-03 1999-04-28 Djupesland Per G Device
GB0121568D0 (en) * 2001-09-06 2001-10-24 Optinose As Nasal delivery device
GB0114272D0 (en) * 2001-06-12 2001-08-01 Optinose As Nasal delivery device
JP3678955B2 (ja) 1999-09-28 2005-08-03 株式会社日立製作所 鼻腔用投薬器
GB0015309D0 (en) * 2000-06-21 2000-08-16 Djupesland Per G Apparatus
ZA200306564B (en) 2001-02-26 2004-10-15 Optinose As Nasal devices.
ES2363333T3 (es) * 2001-11-14 2011-08-01 Novartis Ag Aparato de pulverización de aerosol que comprende un cuerpo y una pieza terminal conectables.
GB0207422D0 (en) * 2002-03-28 2002-05-08 Optinose As Nasal devices
GB0207817D0 (en) 2002-04-04 2002-05-15 Optinose As Nasal devices
SE0201213D0 (sv) * 2002-04-23 2002-04-23 Siemens Elema Ab Anaesthetic Filter Arrangement
GB0209494D0 (en) 2002-04-25 2002-06-05 Optinose As Nasal devices
GB0215270D0 (en) * 2002-07-02 2002-08-14 Optinose As Nasal devices
GB0215904D0 (en) * 2002-07-09 2002-08-21 Team Holdings Uk Ltd Drug delivery system and method
GB0300008D0 (en) 2003-01-02 2003-02-05 Optinose As Delivery devices
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
US20060254583A1 (en) 2003-03-20 2006-11-16 Arthur Deboeck Dry powder inhaler system
GB0311570D0 (en) 2003-05-20 2003-06-25 Optinose As Delivery device and method
GB0319119D0 (en) 2003-08-14 2003-09-17 Optinose As Delivery devices
GB0320171D0 (en) 2003-08-28 2003-10-01 Optinose As Delivery devices
DE10352277A1 (de) 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
USD530815S1 (en) 2004-03-19 2006-10-24 Optinose As Nasal delivery device
GB0420513D0 (en) 2004-09-15 2004-10-20 Optinose As Powder delivery devices
GB0503738D0 (en) 2005-02-23 2005-03-30 Optinose As Powder delivery devices
CA2642608C (en) 2006-01-19 2018-05-29 Optinose As Nasal administration
GB0602980D0 (en) 2006-02-14 2006-03-29 Optinose As Delivery device and method
WO2007093784A1 (en) 2006-02-14 2007-08-23 Optinose As Delivery device and method
GB0604319D0 (en) * 2006-03-03 2006-04-12 Optinose As Nasal delivery
GB0604444D0 (en) 2006-03-06 2006-04-12 Optinose As Nasal devices
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
GB2437488A (en) * 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
GB2438834A (en) 2006-06-08 2007-12-12 Optinose As Intranasal protein administration
GB2440316A (en) 2006-07-25 2008-01-30 Optinose As Nasal inhaler with scrubber
GB0623731D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery device
GB0623732D0 (en) 2006-11-28 2007-01-10 Optinose As Powder delivery devices
GB0623728D0 (en) 2006-11-28 2007-01-10 Optinose As Delivery devices
GB2448193A (en) * 2007-04-05 2008-10-08 Optinose As Nasal delivery device
GB2448183A (en) 2007-04-05 2008-10-08 Optinose As Nasal powder delivery device
GB0719299D0 (en) 2007-10-03 2007-11-14 Optinose As Nasal delivery devices
WO2010029441A2 (en) 2008-09-15 2010-03-18 Optinose As Nasal delivery
GB201015371D0 (en) 2010-09-14 2010-10-27 Optinose As Nasal delivery
WO2012123819A1 (en) 2011-03-15 2012-09-20 Optinose As Et Al Nasal delivery
MX358062B (es) 2012-02-24 2018-08-03 Optinose As Dispositivos de suministro nasal.
JP6243360B2 (ja) 2012-02-24 2017-12-06 オプティノーズ アズ 経鼻配送装置
MX358061B (es) 2012-02-24 2018-08-03 Optinose As Dispositivos de suministro nasal.
US11554229B2 (en) 2013-03-26 2023-01-17 OptiNose Inc. Nasal administration
JP6675974B2 (ja) 2013-03-26 2020-04-08 オプティノーズ アズ 経鼻投与
USD723156S1 (en) 2013-05-23 2015-02-24 Optinose As Nasal delivery device
USD761951S1 (en) 2013-05-23 2016-07-19 Optinose As Nosepiece unit
USD725769S1 (en) 2013-05-23 2015-03-31 Optinose As Nasal delivery device
AU2015348301B2 (en) 2014-11-19 2020-09-03 Optinose, Inc. Intranasal administration

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