BRPI0513293A - solução de infusão ou injeção de levodopa, seringa descartável, e, cassete de bomba de infusão - Google Patents
solução de infusão ou injeção de levodopa, seringa descartável, e, cassete de bomba de infusãoInfo
- Publication number
- BRPI0513293A BRPI0513293A BRPI0513293-2A BRPI0513293A BRPI0513293A BR PI0513293 A BRPI0513293 A BR PI0513293A BR PI0513293 A BRPI0513293 A BR PI0513293A BR PI0513293 A BRPI0513293 A BR PI0513293A
- Authority
- BR
- Brazil
- Prior art keywords
- levodopa
- infusion
- injection solution
- pump cassette
- disposable syringe
- Prior art date
Links
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 title abstract 10
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 title abstract 10
- 229960004502 levodopa Drugs 0.000 title abstract 10
- 238000001802 infusion Methods 0.000 title abstract 8
- 239000000243 solution Substances 0.000 title abstract 7
- 238000002347 injection Methods 0.000 title abstract 5
- 239000007924 injection Substances 0.000 title abstract 5
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SOLUçãO DE INFUSãO OU INJEçãO DE LEVODOPA, SERINGA DESCARTáVEL, E, CASSETE DE BOMBA DE INFUSãO A invenção refere-se a uma solução de infusão ou injeção de Levodopa, que contém pelo menos 10 mg/ml de Levodopa, ou pelo menos 5 mg/ml de Levodopa juntamente com pelo menos 0,5 mg/ml de pelo menos um inibidor de uma enzima metabolizadora de Levodopa. A solução também contém um tampão, um açúcar fisiologicamente aceitável, tal como glicose, um ácido fisiologicamente aceitável, tal como ácido clorídrico, e opcionalmente um estabilizante, e com o pH da solução sendo menor que ou igual a 6. E também descrita uma seringa descartável contendo uma solução de infusão ou injeção de Levodopa, opcionalmente junto como uma enzima metabolizadora de Levodopa, e um cassete de bomba de infusão contendo uma solução de infusão ou injeção de Levodopa opcionalmente juntamente com uma enzima metabolizadora de Levodopa.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401842A SE0401842D0 (sv) | 2004-07-12 | 2004-07-12 | Infusion and injection solution of levodopa |
| PCT/SE2005/001135 WO2006006929A1 (en) | 2004-07-12 | 2005-07-08 | Infusion and injection solution of levodopa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0513293A true BRPI0513293A (pt) | 2008-05-06 |
Family
ID=32867227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0513293-2A BRPI0513293A (pt) | 2004-07-12 | 2005-07-08 | solução de infusão ou injeção de levodopa, seringa descartável, e, cassete de bomba de infusão |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US20080255235A1 (pt) |
| EP (2) | EP2298281B1 (pt) |
| JP (3) | JP2008505966A (pt) |
| KR (1) | KR20070042172A (pt) |
| CN (1) | CN101022784B (pt) |
| AU (1) | AU2005262918B2 (pt) |
| BR (1) | BRPI0513293A (pt) |
| CA (1) | CA2574437C (pt) |
| CY (1) | CY1116197T1 (pt) |
| DK (1) | DK1773297T3 (pt) |
| EA (1) | EA012415B1 (pt) |
| ES (1) | ES2534596T3 (pt) |
| HK (1) | HK1111347A1 (pt) |
| HR (1) | HRP20150384T1 (pt) |
| IL (1) | IL180650A (pt) |
| MX (2) | MX349829B (pt) |
| PL (1) | PL1773297T3 (pt) |
| PT (1) | PT1773297E (pt) |
| SE (1) | SE0401842D0 (pt) |
| SI (1) | SI1773297T1 (pt) |
| WO (1) | WO2006006929A1 (pt) |
| ZA (1) | ZA200700993B (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8815950B2 (en) | 2003-08-29 | 2014-08-26 | Janssen Biotech, Inc. | Pharmaceutical compositions and method of using levodopa and carbidopa |
| BRPI1011031B8 (pt) * | 2009-05-19 | 2021-05-25 | Neuroderm Ltd | composição líquida farmaceuticamente aceitável e kit |
| HUE037005T2 (hu) * | 2010-11-15 | 2018-08-28 | Neuroderm Ltd | L-dopának, dopa dekarboxiláz inhibitoroknak, katechol-O-metil transzferáz inhibitoroknak és ezekhez szolgáló kompozícióknak folyamatos bevezetése |
| EP2648716A4 (en) * | 2010-12-10 | 2015-05-20 | Synagile Corp | PRODUCT COMPOSITIONS OF SUVUTABLY PERFUSABLE LÉVODOPA |
| EP3533447B1 (en) * | 2012-03-20 | 2023-03-15 | Eagle Pharmaceuticals, Inc. | Bendamustine liquid compositions for use in method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration |
| MX2014013556A (es) * | 2012-05-10 | 2015-01-16 | Aop Orphan Pharmaceuticals Ag | Formulacion parenteral de esmolol. |
| WO2013183055A1 (en) | 2012-06-05 | 2013-12-12 | Neuroderm Ltd | Compositions comprising apomorphine and organic acids and uses thereof |
| AU2013334947B2 (en) * | 2012-10-22 | 2018-08-09 | Civitas Therapeutics, Inc. | Reducing inter-patient variability of levodopa plasma concentrations |
| BR112015010601B1 (pt) * | 2012-11-09 | 2022-07-19 | Civitas Therapeutics, Inc. | Composição farmacêutica e uso da composição |
| US20150182698A1 (en) * | 2013-12-31 | 2015-07-02 | Abbvie Inc. | Pump, motor and assembly for beneficial agent delivery |
| US10130755B2 (en) * | 2013-12-31 | 2018-11-20 | Abbvie Inc. | Devices and methods for delivering a beneficial agent to a user |
| AU2015228369B2 (en) | 2014-03-13 | 2020-05-21 | Neuroderm Ltd | DOPA decarboxylase inhibitor compositions |
| US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
| BE1022042B1 (nl) | 2014-09-29 | 2016-02-08 | Puratos Nv | Verbeterde cakebeslagsoorten |
| KR20180004756A (ko) | 2015-05-06 | 2018-01-12 | 신애질 코포레이션 | 약물 입자를 함유하는 제약 현탁액, 그의 투여를 위한 장치, 및 그의 사용 방법 |
| WO2017177262A1 (en) * | 2016-04-11 | 2017-10-19 | University Of Canberra | Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier |
| CN110753538A (zh) * | 2017-06-05 | 2020-02-04 | 迪兹林制药公司 | 左旋多巴输注溶液 |
| RU2676761C1 (ru) * | 2017-10-09 | 2019-01-11 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Полиионный инфузионный раствор |
| WO2019238423A1 (en) | 2018-06-12 | 2019-12-19 | Novozymes A/S | Less added sugar in baked products |
| JP2023547460A (ja) | 2020-11-02 | 2023-11-10 | ノボザイムス アクティーゼルスカブ | ペニシリウム属（ｐｅｎｉｃｉｌｌｕｍ）からの熱安定性ａｍｇ多様体を有する焼成品及び下焼き品 |
| US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
| US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
| US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
| WO2023213424A1 (en) | 2022-05-04 | 2023-11-09 | Novozymes A/S | Brewing with thermostable amg variants |
| WO2024046595A1 (en) | 2022-09-01 | 2024-03-07 | Novozymes A/S | Baking with thermostable amyloglucosidase (amg) variants (ec 3.2.1.3) and low added sugar |
| WO2024046594A1 (en) | 2022-09-01 | 2024-03-07 | Novozymes A/S | Baking with thermostable amg glucosidase variants (ec 3.2.1.3) and low or no added emulsifier |
| WO2024088549A1 (en) | 2022-10-24 | 2024-05-02 | Novozymes A/S | Baking method with thermostable amg variant and alpha-amylase |
| WO2024088550A1 (en) | 2022-10-24 | 2024-05-02 | Novozymes A/S | Baking method for pulse protein fortified bread employing thermostable amyloglucosidase variante (ec 3.2.1.3) |
| WO2024118096A1 (en) | 2022-11-30 | 2024-06-06 | Novozymes A/S | Baking at low-ph with thermostable glucoamylase variants |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5518688B2 (pt) * | 1972-12-02 | 1980-05-21 | ||
| JPS5537528B2 (pt) * | 1972-12-11 | 1980-09-29 | ||
| JPS54105221A (en) * | 1978-02-02 | 1979-08-18 | Sankyo Co Ltd | Preparation of stable concentrated dopa injection |
| JPS6021570B2 (ja) * | 1978-07-04 | 1985-05-28 | 三共株式会社 | ド−パ類の高濃度製剤の製法 |
| EP0252290B1 (en) * | 1986-06-10 | 1992-06-03 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical compositions containing levodopa methyl ester, preparation and therapeutic applications thereof |
| US4850980A (en) * | 1987-12-04 | 1989-07-25 | Fisher Scientific Company | I.V. pump cassette |
| CA2037178A1 (en) * | 1990-02-28 | 1991-08-29 | Albert Walter Brzeczko | Deprenyl/l-dopa/carbidopa pharmaceutical composition |
| US5877176A (en) | 1991-12-26 | 1999-03-02 | Cornell Research Foundation, Inc. | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis |
| US5354885A (en) * | 1992-12-24 | 1994-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Process for preparing ethyl ester of L-DOPA |
| SE512655C2 (sv) | 1993-11-17 | 2000-04-17 | Medmera Sweden Hb C O Nil Dizd | Infusionslösning för medicinskt bruk innehållande L-dopa |
| JP3865450B2 (ja) | 1997-02-14 | 2007-01-10 | 田辺製薬株式会社 | パーキンソニズム治療剤 |
| FR2777781B1 (fr) * | 1998-04-24 | 2004-04-09 | Rhone Poulenc Rorer Sa | Associations riluzole et l-dopa pour le traitement de la maladie de parkinson |
| FI109453B (fi) | 1999-06-30 | 2002-08-15 | Orion Yhtymae Oyj | Farmaseuttinen koostumus |
| DE10261808A1 (de) | 2002-12-19 | 2004-07-08 | Turicum Drug Development Ag | Verwendung von L-DOPA, seiner Derivate und diese Verbindungen enthaltender Arzneimittel zur Prophylaxe psychotischer Erkrankungen |
| CA2536175C (en) | 2003-08-29 | 2013-05-28 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions and method of using levodopa and carbidopa |
-
2004
- 2004-07-12 SE SE0401842A patent/SE0401842D0/xx unknown
-
2005
- 2005-07-08 JP JP2007521433A patent/JP2008505966A/ja active Pending
- 2005-07-08 SI SI200531958T patent/SI1773297T1/sl unknown
- 2005-07-08 ES ES05757066.5T patent/ES2534596T3/es active Active
- 2005-07-08 DK DK05757066T patent/DK1773297T3/en active
- 2005-07-08 CA CA2574437A patent/CA2574437C/en not_active Expired - Fee Related
- 2005-07-08 EP EP10181105.7A patent/EP2298281B1/en active Active
- 2005-07-08 AU AU2005262918A patent/AU2005262918B2/en not_active Ceased
- 2005-07-08 BR BRPI0513293-2A patent/BRPI0513293A/pt not_active Application Discontinuation
- 2005-07-08 MX MX2013006111A patent/MX349829B/es unknown
- 2005-07-08 WO PCT/SE2005/001135 patent/WO2006006929A1/en active Application Filing
- 2005-07-08 MX MX2007000406A patent/MX2007000406A/es active IP Right Grant
- 2005-07-08 KR KR1020077003232A patent/KR20070042172A/ko active Search and Examination
- 2005-07-08 PT PT57570665T patent/PT1773297E/pt unknown
- 2005-07-08 EP EP05757066.5A patent/EP1773297B1/en active Active
- 2005-07-08 PL PL05757066T patent/PL1773297T3/pl unknown
- 2005-07-08 ZA ZA200700993A patent/ZA200700993B/xx unknown
- 2005-07-08 EA EA200700020A patent/EA012415B1/ru not_active IP Right Cessation
- 2005-07-08 US US11/631,602 patent/US20080255235A1/en not_active Abandoned
- 2005-07-08 CN CN200580029688.5A patent/CN101022784B/zh not_active Expired - Fee Related
-
2007
- 2007-01-11 IL IL180650A patent/IL180650A/en active IP Right Grant
-
2008
- 2008-02-21 HK HK08101908.1A patent/HK1111347A1/zh not_active IP Right Cessation
-
2011
- 2011-08-12 US US13/208,628 patent/US8735382B2/en active Active
-
2012
- 2012-08-23 JP JP2012183865A patent/JP2013028609A/ja active Pending
-
2014
- 2014-04-14 US US14/251,967 patent/US9248113B2/en active Active
-
2015
- 2015-04-02 HR HRP20150384TT patent/HRP20150384T1/hr unknown
- 2015-04-09 CY CY20151100347T patent/CY1116197T1/el unknown
- 2015-06-24 JP JP2015126946A patent/JP2015227341A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
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