BRPI0414784B8 - método e dispositivo para detectar quantidades muito pequenas de partículas - Google Patents

método e dispositivo para detectar quantidades muito pequenas de partículas

Info

Publication number
BRPI0414784B8
BRPI0414784B8 BRPI0414784A BRPI0414784A BRPI0414784B8 BR PI0414784 B8 BRPI0414784 B8 BR PI0414784B8 BR PI0414784 A BRPI0414784 A BR PI0414784A BR PI0414784 A BRPI0414784 A BR PI0414784A BR PI0414784 B8 BRPI0414784 B8 BR PI0414784B8
Authority
BR
Brazil
Prior art keywords
particles
detecting
small amounts
verification
atomolar
Prior art date
Application number
BRPI0414784A
Other languages
English (en)
Inventor
Constantin Odefey
Original Assignee
Constantin Odefey
Werner Friedrich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Constantin Odefey, Werner Friedrich filed Critical Constantin Odefey
Publication of BRPI0414784A publication Critical patent/BRPI0414784A/pt
Publication of BRPI0414784B1 publication Critical patent/BRPI0414784B1/pt
Publication of BRPI0414784B8 publication Critical patent/BRPI0414784B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Plasma & Fusion (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Geophysics And Detection Of Objects (AREA)

Abstract

"método e dispositivo para detectar quantidades muito pequenas de partículas". a invenção se refere a um método e a um dispositivo para detectar quantidades muito pequenas de partículas por meio da verificação de produtos de reação, anticorpos, antígenos, através do que o método apresenta uma sensibilidade muito elevada da verificação até em uma escala femtomolar ou atomolar.
BRPI0414784A 2003-09-25 2004-09-09 método e dispositivo para detectar quantidades muito pequenas de partículas BRPI0414784B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10344924.8 2003-09-25
DE10344924A DE10344924A1 (de) 2003-09-25 2003-09-25 Verfahren und Vorrichtung zum Nachweis sehr geringer Partikelmengen
PCT/EP2004/052109 WO2005031325A1 (de) 2003-09-25 2004-09-09 Verfahren und vorrichtung zum nachweis sehr geringer partikelmengen

Publications (3)

Publication Number Publication Date
BRPI0414784A BRPI0414784A (pt) 2006-11-21
BRPI0414784B1 BRPI0414784B1 (pt) 2018-02-06
BRPI0414784B8 true BRPI0414784B8 (pt) 2021-07-27

Family

ID=34384313

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414784A BRPI0414784B8 (pt) 2003-09-25 2004-09-09 método e dispositivo para detectar quantidades muito pequenas de partículas

Country Status (25)

Country Link
US (1) US7547554B2 (pt)
EP (1) EP1664747B1 (pt)
JP (1) JP4959330B2 (pt)
KR (1) KR100802449B1 (pt)
CN (1) CN100501385C (pt)
AT (1) ATE360812T1 (pt)
AU (1) AU2004276506B2 (pt)
BR (1) BRPI0414784B8 (pt)
CA (1) CA2539910C (pt)
CY (1) CY1106648T1 (pt)
DE (2) DE10344924A1 (pt)
DK (1) DK1664747T3 (pt)
EA (1) EA008859B1 (pt)
ES (1) ES2285507T3 (pt)
HK (1) HK1091901A1 (pt)
HR (1) HRP20060118B1 (pt)
IL (1) IL174032A (pt)
MX (1) MXPA06003324A (pt)
NO (1) NO338340B1 (pt)
NZ (1) NZ546029A (pt)
PL (1) PL1664747T3 (pt)
PT (1) PT1664747E (pt)
SI (1) SI1664747T1 (pt)
UA (1) UA85560C2 (pt)
WO (1) WO2005031325A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2010047419A1 (en) * 2008-10-24 2010-04-29 Fujifilm Corporation Immobilization substrate and method for producing the same
EP2576759A4 (en) 2010-05-25 2014-01-22 Arryx Inc METHODS AND APPARATUSES FOR DETECTING FREEDOM OF POSITION OF PARTICLES IN BIOLOGICAL AND CHEMICAL ANALYZES AND APPLICATION IN IMMUNODIAGNOSTICS
FR2963103B1 (fr) * 2010-07-22 2012-08-24 Commissariat Energie Atomique Procede d'estimation de la quantite d'entites deposees sur des microparticules en suspension dans une solution, dispositif associe et utilisation de ce dispositif
WO2012027747A2 (en) 2010-08-27 2012-03-01 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
CN103267956A (zh) * 2013-05-17 2013-08-28 南通大学 一种磁响应特性检测系统
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
EP3147028B1 (de) 2015-09-25 2019-06-19 Constantin Odefey Verfahren und system zur magnetischen trennung von nano-beads

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5100805A (en) * 1989-01-26 1992-03-31 Seradyn, Inc. Quantitative immunoassay system and method for agglutination assays
EP0414224B1 (en) * 1989-08-23 1996-06-12 Canon Kabushiki Kaisha Method for measuring an immunologically active material and apparatus suitable for practising said method
JPH0545282A (ja) * 1991-08-09 1993-02-23 Kurabo Ind Ltd 自動臨床分析システム
JP3283078B2 (ja) * 1992-12-04 2002-05-20 興和株式会社 免疫学的測定装置

Also Published As

Publication number Publication date
IL174032A (en) 2010-05-17
EP1664747B1 (de) 2007-04-25
HK1091901A1 (en) 2007-01-26
AU2004276506B2 (en) 2009-11-12
WO2005031325A1 (de) 2005-04-07
CN1853096A (zh) 2006-10-25
DE10344924A1 (de) 2005-05-04
EA008859B1 (ru) 2007-08-31
NO338340B1 (no) 2016-08-08
IL174032A0 (en) 2006-08-01
US20070054417A1 (en) 2007-03-08
ES2285507T3 (es) 2007-11-16
KR100802449B1 (ko) 2008-02-13
AU2004276506A1 (en) 2005-04-07
DE502004003637D1 (de) 2007-06-06
CY1106648T1 (el) 2012-01-25
HRP20060118B1 (en) 2011-12-31
PT1664747E (pt) 2007-05-31
DK1664747T3 (da) 2007-08-20
ATE360812T1 (de) 2007-05-15
JP4959330B2 (ja) 2012-06-20
BRPI0414784B1 (pt) 2018-02-06
HRP20060118A2 (en) 2006-05-31
KR20060091305A (ko) 2006-08-18
EP1664747A1 (de) 2006-06-07
CA2539910A1 (en) 2005-04-07
CA2539910C (en) 2012-06-19
PL1664747T3 (pl) 2007-10-31
MXPA06003324A (es) 2006-06-08
NO20061824L (no) 2006-04-25
SI1664747T1 (sl) 2007-08-31
NZ546029A (en) 2008-12-24
US7547554B2 (en) 2009-06-16
JP2007506954A (ja) 2007-03-22
BRPI0414784A (pt) 2006-11-21
CN100501385C (zh) 2009-06-17
UA85560C2 (uk) 2009-02-10
WO2005031325B1 (de) 2005-06-02
EA200600387A1 (ru) 2006-10-27

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/09/2004, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 17A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2640 DE 10-08-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.