EA200600387A1 - Устройство и способ для детектирования очень малых количеств частиц - Google Patents

Устройство и способ для детектирования очень малых количеств частиц

Info

Publication number
EA200600387A1
EA200600387A1 EA200600387A EA200600387A EA200600387A1 EA 200600387 A1 EA200600387 A1 EA 200600387A1 EA 200600387 A EA200600387 A EA 200600387A EA 200600387 A EA200600387 A EA 200600387A EA 200600387 A1 EA200600387 A1 EA 200600387A1
Authority
EA
Eurasian Patent Office
Prior art keywords
particles
detection
small amount
femtomolar
antigen
Prior art date
Application number
EA200600387A
Other languages
English (en)
Other versions
EA008859B1 (ru
Inventor
Константин Одефей
Original Assignee
Вернер, Фридрих
Константин Одефей
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вернер, Фридрих, Константин Одефей filed Critical Вернер, Фридрих
Publication of EA200600387A1 publication Critical patent/EA200600387A1/ru
Publication of EA008859B1 publication Critical patent/EA008859B1/ru

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Geophysics And Detection Of Objects (AREA)

Abstract

Изобретение относится к способу и устройству для детектирования очень малых количеств частиц. Заявленный в изобретении способ основан на детектировании продуктов взаимодействия антиген-антитело и обеспечивает очень высокую чувствительность детектирования вплоть до фемтомолярного или аттомолярного диапазона.
EA200600387A 2003-09-25 2004-09-09 Способ и устройство для детектирования очень малых количеств частиц EA008859B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10344924A DE10344924A1 (de) 2003-09-25 2003-09-25 Verfahren und Vorrichtung zum Nachweis sehr geringer Partikelmengen
PCT/EP2004/052109 WO2005031325A1 (de) 2003-09-25 2004-09-09 Verfahren und vorrichtung zum nachweis sehr geringer partikelmengen

Publications (2)

Publication Number Publication Date
EA200600387A1 true EA200600387A1 (ru) 2006-10-27
EA008859B1 EA008859B1 (ru) 2007-08-31

Family

ID=34384313

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600387A EA008859B1 (ru) 2003-09-25 2004-09-09 Способ и устройство для детектирования очень малых количеств частиц

Country Status (25)

Country Link
US (1) US7547554B2 (ru)
EP (1) EP1664747B1 (ru)
JP (1) JP4959330B2 (ru)
KR (1) KR100802449B1 (ru)
CN (1) CN100501385C (ru)
AT (1) ATE360812T1 (ru)
AU (1) AU2004276506B2 (ru)
BR (1) BRPI0414784B8 (ru)
CA (1) CA2539910C (ru)
CY (1) CY1106648T1 (ru)
DE (2) DE10344924A1 (ru)
DK (1) DK1664747T3 (ru)
EA (1) EA008859B1 (ru)
ES (1) ES2285507T3 (ru)
HK (1) HK1091901A1 (ru)
HR (1) HRP20060118B1 (ru)
IL (1) IL174032A (ru)
MX (1) MXPA06003324A (ru)
NO (1) NO338340B1 (ru)
NZ (1) NZ546029A (ru)
PL (1) PL1664747T3 (ru)
PT (1) PT1664747E (ru)
SI (1) SI1664747T1 (ru)
UA (1) UA85560C2 (ru)
WO (1) WO2005031325A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
US9487592B2 (en) * 2008-10-24 2016-11-08 Fujifilm Corporation Immobilization substrate and method for producing the same
JP2013533469A (ja) 2010-05-25 2013-08-22 アリックス インク 免疫診断における生物学的および化学的分析および用途における粒子の位置的自由度の検出のための方法および装置
FR2963103B1 (fr) * 2010-07-22 2012-08-24 Commissariat Energie Atomique Procede d'estimation de la quantite d'entites deposees sur des microparticules en suspension dans une solution, dispositif associe et utilisation de ce dispositif
US8846331B2 (en) 2010-08-27 2014-09-30 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
CN103267956A (zh) * 2013-05-17 2013-08-28 南通大学 一种磁响应特性检测系统
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
EP3147028B1 (de) 2015-09-25 2019-06-19 Constantin Odefey Verfahren und system zur magnetischen trennung von nano-beads

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5100805A (en) 1989-01-26 1992-03-31 Seradyn, Inc. Quantitative immunoassay system and method for agglutination assays
EP0414224B1 (en) * 1989-08-23 1996-06-12 Canon Kabushiki Kaisha Method for measuring an immunologically active material and apparatus suitable for practising said method
JPH0545282A (ja) * 1991-08-09 1993-02-23 Kurabo Ind Ltd 自動臨床分析システム
JP3283078B2 (ja) * 1992-12-04 2002-05-20 興和株式会社 免疫学的測定装置

Also Published As

Publication number Publication date
DK1664747T3 (da) 2007-08-20
BRPI0414784A (pt) 2006-11-21
ATE360812T1 (de) 2007-05-15
KR100802449B1 (ko) 2008-02-13
US7547554B2 (en) 2009-06-16
IL174032A0 (en) 2006-08-01
ES2285507T3 (es) 2007-11-16
PT1664747E (pt) 2007-05-31
JP4959330B2 (ja) 2012-06-20
PL1664747T3 (pl) 2007-10-31
HRP20060118A2 (en) 2006-05-31
NO338340B1 (no) 2016-08-08
BRPI0414784B8 (pt) 2021-07-27
MXPA06003324A (es) 2006-06-08
WO2005031325B1 (de) 2005-06-02
BRPI0414784B1 (pt) 2018-02-06
AU2004276506B2 (en) 2009-11-12
AU2004276506A1 (en) 2005-04-07
EP1664747A1 (de) 2006-06-07
EA008859B1 (ru) 2007-08-31
DE10344924A1 (de) 2005-05-04
CY1106648T1 (el) 2012-01-25
HK1091901A1 (en) 2007-01-26
CA2539910C (en) 2012-06-19
SI1664747T1 (sl) 2007-08-31
HRP20060118B1 (en) 2011-12-31
CN1853096A (zh) 2006-10-25
KR20060091305A (ko) 2006-08-18
US20070054417A1 (en) 2007-03-08
JP2007506954A (ja) 2007-03-22
UA85560C2 (ru) 2009-02-10
CA2539910A1 (en) 2005-04-07
CN100501385C (zh) 2009-06-17
DE502004003637D1 (de) 2007-06-06
IL174032A (en) 2010-05-17
WO2005031325A1 (de) 2005-04-07
NZ546029A (en) 2008-12-24
NO20061824L (no) 2006-04-25
EP1664747B1 (de) 2007-04-25

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU