BRPI0315315B1 - Use of a therapeutically effective amount of 3- (4-amino-1-oxo-1,3-dihydro-isoindol-2-yl) -piperidine-2,6-diona or a pharmaceutically acceptable salt of the same for the preparation of a medication to treat a myelodisplasica syndrome - Google Patents

Use of a therapeutically effective amount of 3- (4-amino-1-oxo-1,3-dihydro-isoindol-2-yl) -piperidine-2,6-diona or a pharmaceutically acceptable salt of the same for the preparation of a medication to treat a myelodisplasica syndrome Download PDF

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Publication number
BRPI0315315B1
BRPI0315315B1 BRPI0315315-0A BR0315315A BRPI0315315B1 BR PI0315315 B1 BRPI0315315 B1 BR PI0315315B1 BR 0315315 A BR0315315 A BR 0315315A BR PI0315315 B1 BRPI0315315 B1 BR PI0315315B1
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BR
Brazil
Prior art keywords
patients
mds
oxo
amino
pharmaceutically acceptable
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BRPI0315315-0A
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Portuguese (pt)
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BRPI0315315B8 (enExample
BR0315315A (pt
Inventor
B. Zeldis Jerome
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Celgene Corporation
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Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of BR0315315A publication Critical patent/BR0315315A/pt
Publication of BRPI0315315B1 publication Critical patent/BRPI0315315B1/pt
Publication of BRPI0315315B8 publication Critical patent/BRPI0315315B8/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
BRPI0315315-0A 2002-10-15 2003-04-13 Use of a therapeutically effective amount of 3- (4-amino-1-oxo-1,3-dihydro-isoindol-2-yl) -piperidine-2,6-diona or a pharmaceutically acceptable salt of the same for the preparation of a medication to treat a myelodisplasica syndrome BRPI0315315B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41846802P 2002-10-15 2002-10-15
US60/418,468 2002-10-15
PCT/US2003/011323 WO2004035064A1 (en) 2002-10-15 2003-04-13 Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes

Publications (3)

Publication Number Publication Date
BR0315315A BR0315315A (pt) 2005-08-16
BRPI0315315B1 true BRPI0315315B1 (pt) 2017-09-19
BRPI0315315B8 BRPI0315315B8 (enExample) 2021-05-25

Family

ID=32107932

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0315315-0A BRPI0315315B1 (pt) 2002-10-15 2003-04-13 Use of a therapeutically effective amount of 3- (4-amino-1-oxo-1,3-dihydro-isoindol-2-yl) -piperidine-2,6-diona or a pharmaceutically acceptable salt of the same for the preparation of a medication to treat a myelodisplasica syndrome

Country Status (19)

Country Link
US (3) US7189740B2 (enExample)
EP (1) EP1487461B1 (enExample)
JP (2) JP4481828B2 (enExample)
KR (2) KR20070020141A (enExample)
CN (2) CN100579527C (enExample)
AT (1) ATE390135T1 (enExample)
AU (2) AU2003228508B2 (enExample)
BR (1) BRPI0315315B1 (enExample)
CA (1) CA2477301C (enExample)
DE (1) DE60319967T2 (enExample)
DK (1) DK1487461T3 (enExample)
ES (1) ES2304509T3 (enExample)
IL (1) IL168061A (enExample)
MX (2) MXPA05003888A (enExample)
NZ (2) NZ539533A (enExample)
PT (1) PT1487461E (enExample)
SI (1) SI1487461T1 (enExample)
WO (1) WO2004035064A1 (enExample)
ZA (1) ZA200503025B (enExample)

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