BRPI0211151B8 - composição vacinal e método de fabricação da mesma - Google Patents

composição vacinal e método de fabricação da mesma

Info

Publication number
BRPI0211151B8
BRPI0211151B8 BRPI0211151A BRPI0211151B8 BR PI0211151 B8 BRPI0211151 B8 BR PI0211151B8 BR PI0211151 A BRPI0211151 A BR PI0211151A BR PI0211151 B8 BRPI0211151 B8 BR PI0211151B8
Authority
BR
Brazil
Prior art keywords
valence
vaccine composition
aluminum hydroxide
manufacturing
adsorbed
Prior art date
Application number
Other languages
English (en)
Inventor
Françon Alain
Original Assignee
Aventis Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8866367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0211151(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pasteur filed Critical Aventis Pasteur
Publication of BR0211151A publication Critical patent/BR0211151A/pt
Publication of BRPI0211151B1 publication Critical patent/BRPI0211151B1/pt
Publication of BRPI0211151B8 publication Critical patent/BRPI0211151B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

composição vacinal e método de fabricação da mesma. a invenção tem por objeto uma composição vacinal, que compreende pelo menos duas valências: (i) uma primeira valência que é adjuvantada com o hidróxido de alumínio e (ii) uma segunda valência que contém um poli-sacarídeo de cápsula bacteriana que comporta um ou grupamentos o-acetis e que não é adsorvida sobre o hidróxido alumínio, em virtude da presença de um composto protetor que pode ser um fosfato, um citrato ou ainda um carbonato e que impede essa adsorção. a primeira valência pode ser qualquer valência vacinal. segundo um modo particular, a composição vacinal compreende (i) a valência hepatite a, adsorvida sobre hidróxido de alumínio e (ii) a valência febre tifóide constituída por poli-sacarídeo vi da cápsula de salmonella typhi.
BR0211151-9 2001-08-08 2002-07-31 composição vacinal e método de fabricação da mesma BRPI0211151B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0110573A FR2828406B1 (fr) 2001-08-08 2001-08-08 Composition vaccinale bivalente havi
FR01/10573 2001-08-08
PCT/FR2002/002770 WO2003013600A1 (fr) 2001-08-08 2002-07-31 Composition vaccinale comprenant au moins deux valances, l'une adjuvantee, l'autre pas

Publications (3)

Publication Number Publication Date
BR0211151A BR0211151A (pt) 2004-08-10
BRPI0211151B1 BRPI0211151B1 (pt) 2019-07-09
BRPI0211151B8 true BRPI0211151B8 (pt) 2021-05-25

Family

ID=8866367

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211151-9 BRPI0211151B8 (pt) 2001-08-08 2002-07-31 composição vacinal e método de fabricação da mesma

Country Status (22)

Country Link
US (1) US7404960B2 (pt)
EP (1) EP1416958B2 (pt)
JP (1) JP4221291B2 (pt)
KR (1) KR100881703B1 (pt)
CN (1) CN1282486C (pt)
AT (1) ATE357929T1 (pt)
AU (1) AU2002342949B2 (pt)
BR (1) BRPI0211151B8 (pt)
CA (1) CA2455406C (pt)
CY (1) CY1107619T1 (pt)
DE (1) DE60219177T3 (pt)
DK (1) DK1416958T4 (pt)
ES (1) ES2284940T5 (pt)
FR (1) FR2828406B1 (pt)
HU (1) HU228216B1 (pt)
IL (2) IL159519A0 (pt)
MX (1) MXPA04001125A (pt)
NZ (1) NZ530727A (pt)
PL (1) PL215134B1 (pt)
PT (1) PT1416958E (pt)
WO (1) WO2003013600A1 (pt)
ZA (1) ZA200400022B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2464522C (en) 2004-04-15 2011-11-15 Eng-Hong Lee Soft gel delivery system for treating poultry
ES2387582T3 (es) * 2006-09-07 2012-09-26 Glaxosmithkline Biologicals S.A. Vacuna de combinación con cantidades reducidas del antígeno del virus de la polio
KR101101901B1 (ko) * 2009-01-30 2012-01-02 주식회사 리노 주방용 선반
AU2010227219B2 (en) 2009-03-24 2014-02-27 Glaxosmithkline Biologicals S.A. Adjuvanting meningococcal factor H binding protein
CN102526724B (zh) * 2011-01-14 2015-07-22 四川大学 氢氧化铝凝胶-多糖复合免疫佐剂及其制备方法和用途
FR2985663B1 (fr) 2012-01-17 2015-03-27 Sanofi Pasteur Procede de formulation d'un vaccin contenant au moins deux antigenes susceptibles de s'adsorber sur de l'oxy hydroxyde d'aluminium

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2734484B1 (fr) * 1995-05-24 1997-06-27 Pasteur Merieux Serums Vacc Composition vaccinale liquide et procede de fabrication
GB9806456D0 (en) * 1998-03-25 1998-05-27 Smithkline Beecham Biolog Vaccine composition
EP1107787B1 (en) * 1998-08-28 2003-05-14 GlaxoSmithKline Biologicals S.A. Salmonella typhi vaccine compositions
US6585973B1 (en) * 1998-10-29 2003-07-01 Henry M. Jackson Foundation For The Advancement Of Military Medicine Method for preparing solid phase conjugated vaccine
GB9909077D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Biolog Novel compositions

Also Published As

Publication number Publication date
CN1282486C (zh) 2006-11-01
KR100881703B1 (ko) 2009-02-06
ES2284940T5 (es) 2012-07-02
BRPI0211151B1 (pt) 2019-07-09
US20040170648A1 (en) 2004-09-02
JP2005501081A (ja) 2005-01-13
PL215134B1 (pl) 2013-10-31
PL367904A1 (en) 2005-03-07
ATE357929T1 (de) 2007-04-15
IL159519A0 (en) 2004-06-01
EP1416958B1 (fr) 2007-03-28
DK1416958T4 (da) 2012-07-09
DE60219177T3 (de) 2012-08-30
MXPA04001125A (es) 2004-05-20
EP1416958B2 (fr) 2012-03-14
HU228216B1 (en) 2013-02-28
US7404960B2 (en) 2008-07-29
NZ530727A (en) 2004-06-25
FR2828406A1 (fr) 2003-02-14
CA2455406A1 (en) 2003-02-20
DE60219177D1 (de) 2007-05-10
ZA200400022B (en) 2006-05-31
EP1416958A1 (fr) 2004-05-12
BR0211151A (pt) 2004-08-10
HUP0401182A3 (en) 2004-10-28
PT1416958E (pt) 2007-05-31
IL159519A (en) 2010-11-30
CY1107619T1 (el) 2013-04-18
ES2284940T3 (es) 2007-11-16
FR2828406B1 (fr) 2005-06-24
HUP0401182A2 (hu) 2004-09-28
DK1416958T3 (da) 2007-07-30
JP4221291B2 (ja) 2009-02-12
CN1541108A (zh) 2004-10-27
CA2455406C (en) 2012-03-13
AU2002342949B2 (en) 2007-07-05
KR20040043182A (ko) 2004-05-22
WO2003013600A1 (fr) 2003-02-20
DE60219177T2 (de) 2008-01-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/07/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/07/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

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