BR9803237A - Derivados de uréia. - Google Patents
Derivados de uréia.Info
- Publication number
- BR9803237A BR9803237A BR9803237-2A BR9803237A BR9803237A BR 9803237 A BR9803237 A BR 9803237A BR 9803237 A BR9803237 A BR 9803237A BR 9803237 A BR9803237 A BR 9803237A
- Authority
- BR
- Brazil
- Prior art keywords
- urea derivatives
- represents hydrogen
- compounds
- halogen
- processes
- Prior art date
Links
- 150000003672 ureas Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical class NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Patente de Invenção:<B>"DERIVADOS DE URéIA"<D>. Descrevem-se compostos de fórmula I em que R^ 1^ representa hidrogênio ou alquila inferior, R^ 2^ representa hidrogênio ou halogênio e R^ 3^ representa hidrogênio ou alcóxi inferior e respectivos sais de adição de ácido fisiologicamente aceitáveis e fármacos contendo estes compostos bem como processos para a sua preparação.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19737274 | 1997-08-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9803237A true BR9803237A (pt) | 2000-02-08 |
BR9803237B1 BR9803237B1 (pt) | 2009-05-05 |
Family
ID=7840297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9803237-2A BR9803237B1 (pt) | 1997-08-27 | 1998-08-26 | derivados de uréia, composição farmacêutica e processo para sua preparação. |
Country Status (24)
Country | Link |
---|---|
US (1) | US6001833A (pt) |
JP (1) | JP4250228B2 (pt) |
KR (1) | KR19990023605A (pt) |
CN (1) | CN1108290C (pt) |
AR (1) | AR015147A1 (pt) |
AU (1) | AU744104B2 (pt) |
BR (1) | BR9803237B1 (pt) |
CA (1) | CA2245484C (pt) |
CZ (1) | CZ267198A3 (pt) |
DE (1) | DE19824865A1 (pt) |
DZ (1) | DZ2597A1 (pt) |
HK (1) | HK1019604A1 (pt) |
HU (1) | HUP9801889A1 (pt) |
ID (1) | ID20787A (pt) |
IL (1) | IL125885A (pt) |
NO (1) | NO314939B1 (pt) |
NZ (1) | NZ331524A (pt) |
PL (1) | PL193724B1 (pt) |
RU (1) | RU2198883C2 (pt) |
SK (1) | SK111098A3 (pt) |
TR (1) | TR199801683A2 (pt) |
TW (1) | TW520368B (pt) |
UA (1) | UA60300C2 (pt) |
ZA (1) | ZA986721B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10036818A1 (de) | 2000-07-28 | 2002-02-07 | Solvay Pharm Gmbh | Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten |
UA75425C2 (en) * | 2001-07-09 | 2006-04-17 | Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds | |
ITBO20020198A1 (it) * | 2002-04-12 | 2003-10-13 | Univ Bologna | Derivati 2 , 5 bis diammino 1 , 4 benzochenionici utili per il trattamento della malattia di alzheimer , metodo per la loro preparazione ed |
US20070082905A1 (en) * | 2005-05-27 | 2007-04-12 | De Vries Michiel H | Pharmaceutical compositions comprising n-triazolymethyl-piperazine compounds and methods of using same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
AU706021B2 (en) * | 1995-05-25 | 1999-06-03 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
GB9519077D0 (en) * | 1995-09-18 | 1995-11-15 | Fujisawa Pharmaceutical Co | New heterocyclic compounds |
FR2744449B1 (fr) * | 1996-02-02 | 1998-04-24 | Pf Medicament | Nouvelles piperazines aromatiques derivees de cycloazanes substitues, ainsi que leur procede de preparation, les compositions pharmaceutiques et leur utilisation comme medicaments |
JP4189043B2 (ja) * | 1996-09-30 | 2008-12-03 | 株式会社資生堂 | N−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
-
1998
- 1998-06-04 DE DE19824865A patent/DE19824865A1/de not_active Ceased
- 1998-07-28 ZA ZA986721A patent/ZA986721B/xx unknown
- 1998-07-28 TW TW087112327A patent/TW520368B/zh not_active IP Right Cessation
- 1998-08-10 AR ARP980103945A patent/AR015147A1/es unknown
- 1998-08-14 SK SK1110-98A patent/SK111098A3/sk unknown
- 1998-08-14 KR KR1019980033038A patent/KR19990023605A/ko not_active Application Discontinuation
- 1998-08-17 HU HU9801889A patent/HUP9801889A1/hu unknown
- 1998-08-21 IL IL12588598A patent/IL125885A/xx not_active IP Right Cessation
- 1998-08-21 CZ CZ982671A patent/CZ267198A3/cs unknown
- 1998-08-24 NZ NZ331524A patent/NZ331524A/en unknown
- 1998-08-24 JP JP23712898A patent/JP4250228B2/ja not_active Expired - Fee Related
- 1998-08-25 CA CA002245484A patent/CA2245484C/en not_active Expired - Fee Related
- 1998-08-25 CN CN98118692A patent/CN1108290C/zh not_active Expired - Fee Related
- 1998-08-26 NO NO19983918A patent/NO314939B1/no unknown
- 1998-08-26 BR BRPI9803237-2A patent/BR9803237B1/pt not_active IP Right Cessation
- 1998-08-26 AU AU81899/98A patent/AU744104B2/en not_active Ceased
- 1998-08-26 DZ DZ980207A patent/DZ2597A1/xx active
- 1998-08-26 UA UA98084604A patent/UA60300C2/uk unknown
- 1998-08-26 RU RU98115953/04A patent/RU2198883C2/ru not_active IP Right Cessation
- 1998-08-26 PL PL328221A patent/PL193724B1/pl not_active IP Right Cessation
- 1998-08-27 TR TR1998/01683A patent/TR199801683A2/xx unknown
- 1998-08-27 US US09/141,623 patent/US6001833A/en not_active Expired - Lifetime
- 1998-08-27 ID IDP981171A patent/ID20787A/id unknown
-
1999
- 1999-10-27 HK HK99104799A patent/HK1019604A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE19824865A1 (de) | 1999-03-04 |
CA2245484A1 (en) | 1999-02-27 |
CN1218044A (zh) | 1999-06-02 |
CN1108290C (zh) | 2003-05-14 |
TW520368B (en) | 2003-02-11 |
NZ331524A (en) | 2000-02-28 |
JP4250228B2 (ja) | 2009-04-08 |
AU744104B2 (en) | 2002-02-14 |
UA60300C2 (uk) | 2003-10-15 |
NO314939B1 (no) | 2003-06-16 |
BR9803237B1 (pt) | 2009-05-05 |
SK111098A3 (en) | 1999-05-07 |
TR199801683A3 (tr) | 1999-03-22 |
NO983918L (no) | 1999-03-01 |
DZ2597A1 (fr) | 2003-03-01 |
RU2198883C2 (ru) | 2003-02-20 |
TR199801683A2 (xx) | 1999-03-22 |
US6001833A (en) | 1999-12-14 |
JPH11140082A (ja) | 1999-05-25 |
HU9801889D0 (en) | 1998-10-28 |
CZ267198A3 (cs) | 1999-03-17 |
NO983918D0 (no) | 1998-08-26 |
HK1019604A1 (en) | 2000-02-18 |
IL125885A0 (en) | 1999-04-11 |
ZA986721B (en) | 1999-02-02 |
AU8189998A (en) | 1999-03-11 |
AR015147A1 (es) | 2001-04-18 |
CA2245484C (en) | 2008-04-29 |
PL193724B1 (pl) | 2007-03-30 |
IL125885A (en) | 2000-08-13 |
KR19990023605A (ko) | 1999-03-25 |
PL328221A1 (en) | 1999-03-01 |
ID20787A (id) | 1999-03-04 |
HUP9801889A1 (hu) | 2000-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/05/2009, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 15A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2259 DE 22-04-2014 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |