BR9802403A - Proteìna tendo atividade transglutaminase, dna, transformante, e, processo para produzir uma proteìna tendo uma atividade transglutaminase. - Google Patents
Proteìna tendo atividade transglutaminase, dna, transformante, e, processo para produzir uma proteìna tendo uma atividade transglutaminase.Info
- Publication number
- BR9802403A BR9802403A BR9802403-5A BR9802403A BR9802403A BR 9802403 A BR9802403 A BR 9802403A BR 9802403 A BR9802403 A BR 9802403A BR 9802403 A BR9802403 A BR 9802403A
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- transglutaminase activity
- dna
- transglutaminase
- transformant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
Abstract
"PROTEìNA TENDO ATIVIDADE TRANSGLUTAMINASE, DNA, TRANSFORMANTE, E, PROCESSO PARA PRODUZIR UMA PROTEìNA TENDO UMA ATIVIDADE TRANSGLUTAMINASE". Descreve-se uma proteína tendo atividade transglutaminase que compreende uma sequência na faixa de resíduo serina na segunda posição para resíduo prolina na posição 331, em uma sequência de aminoácido representada pela SEQ. ID. NO.: 1, em que o aminoácido N-terminal da proteína corresponde a resíduo serina na segunda posição da SEQ. ID, NO.: 1, um DNA codificando a proteína, um transformante tendo o DNA e um processo para produzir uma proteína tendo atividade transglutaminase, que compreende as etapas de cultivar o transformante em um meio. A proteína pode ser produzida em uma grande quantidade com o transformante usando um hospedeiro como E.coli.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18001097 | 1997-07-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9802403A true BR9802403A (pt) | 2000-01-11 |
Family
ID=16075884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9802403-5A BR9802403A (pt) | 1997-07-04 | 1998-07-06 | Proteìna tendo atividade transglutaminase, dna, transformante, e, processo para produzir uma proteìna tendo uma atividade transglutaminase. |
Country Status (7)
Country | Link |
---|---|
US (2) | US6013498A (pt) |
EP (1) | EP0889133B1 (pt) |
CN (1) | CN1151252C (pt) |
BR (1) | BR9802403A (pt) |
CA (1) | CA2237041A1 (pt) |
DE (1) | DE69822251T2 (pt) |
DK (1) | DK0889133T3 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0889133B1 (en) * | 1997-07-04 | 2004-03-10 | Ajinomoto Co., Inc. | Process for producing microbial transglutaminase |
US6821763B2 (en) * | 1997-07-04 | 2004-11-23 | Ajinomoto Co., Inc. | Process for producing microbial transglutaminase |
WO2000040706A1 (fr) * | 1998-12-28 | 2000-07-13 | Ajinomoto Co., Inc. | Procede de production de transglutaminase |
BR0014811A (pt) * | 1999-10-18 | 2002-08-27 | Ajinomoto Kk | Bactéria pertencente a streptomyces, e métodos para produzir uma pró-transglutaminase, e, uma transglutaminase madura derivadas de actinomicetos |
CA2419453C (en) * | 2000-08-17 | 2010-03-09 | Ajinomoto Co., Inc. | Mutant transglutaminase from streptoverticillium having modified substrate specificity |
DE10042993B4 (de) | 2000-09-01 | 2005-09-15 | Trumpler Gmbh & Co. Chemische Fabrik | Verfahren zum enzymatischen Gerben von Häuten |
DE10046605A1 (de) | 2000-09-20 | 2002-03-28 | Roehm Enzyme Gmbh | Verwendung von Transglutaminasen zur Herstellung von weizenarmen Backwaren |
JP3951584B2 (ja) | 2000-10-10 | 2007-08-01 | 味の素株式会社 | 改質された原料乳の製造方法及びそれを用いた乳製品 |
US6633800B1 (en) | 2001-01-31 | 2003-10-14 | Ainsworth Inc. | Remote control system |
US6664299B2 (en) * | 2002-02-14 | 2003-12-16 | Dow Corning Corporation | Masterbatch method for economically and efficiently producing soap dispersions in textile fluids for synthetic fiber treatment |
US7101695B2 (en) * | 2002-03-01 | 2006-09-05 | Szu-Yi Chou | Method of producing transglutaminase having broad substrate activity |
US7485438B2 (en) | 2002-03-01 | 2009-02-03 | Szu-Yi Chou | Method of producing polyvalent antigens |
US20030219853A1 (en) * | 2002-03-01 | 2003-11-27 | Szu-Yi Chou | Method of cross-linking a compound |
ES2223227B1 (es) * | 2002-05-31 | 2006-04-16 | Consejo Sup. Investig. Cientificas | Secuencia de nucleotidos de maiz codificante de una proteina con actividad transglutaminasa, y su uso. |
CN101691560B (zh) * | 2008-12-19 | 2011-08-31 | 华南理工大学 | 大肠杆菌及其可溶性表达转谷氨酰胺酶酶原的方法 |
US20100316764A1 (en) * | 2009-06-10 | 2010-12-16 | Engrain, LLC | Flour supplement compositions and methods for preparing wheat flour |
CN102517242A (zh) * | 2011-12-30 | 2012-06-27 | 齐河百多安生物医药科技有限公司 | 一种提高茂原链轮丝菌谷氨酰胺转胺酶表达量的方法及其专用工程菌 |
CN102586167B (zh) * | 2012-03-01 | 2013-07-24 | 华南理工大学 | 一株重组的枯草芽孢杆菌及由其生产转谷氨酰胺酶的方法 |
CN106720302A (zh) * | 2016-11-29 | 2017-05-31 | 中国农业大学 | 一种改善乳蛋白浓缩物凝胶性的方法及其应用 |
JP2021502068A (ja) | 2017-11-07 | 2021-01-28 | コデクシス, インコーポレイテッド | トランスグルタミナーゼバリアント |
CN113528479B (zh) * | 2020-04-13 | 2023-01-24 | 中国科学院微生物研究所 | 一种转谷氨酰胺酶的高效制备方法及其专用工程菌 |
CN111826389B (zh) * | 2020-05-26 | 2022-05-13 | 江南大学 | 提高大肠杆菌重组蛋白胞外分泌水平的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0665280B2 (ja) * | 1987-03-04 | 1994-08-24 | 味の素株式会社 | タンパクゲル化剤及びそれを用いるタンパクのゲル化方法 |
JPS6450382A (en) * | 1987-08-20 | 1989-02-27 | Hitachi Heating Appl | Plane-form heating body |
JP3010589B2 (ja) * | 1990-10-19 | 2000-02-21 | 天野製薬株式会社 | リコンビナントトランスグルタミナーゼ |
DE69116495T2 (de) * | 1990-10-19 | 1996-06-13 | Ajinomoto Kk | Rekombinante Transglutaminase |
DE69333718T2 (de) * | 1992-01-14 | 2005-12-01 | Ajinomoto Co., Inc. | Gen, das für eine Fisch-Transglutaminase kodiert |
JPH0630771A (ja) * | 1992-07-14 | 1994-02-08 | Ajinomoto Co Inc | バクテリアルトランスグルタミナーゼの製造法及び関連物 |
US5736356A (en) * | 1994-01-28 | 1998-04-07 | Ajinomoto Co., Inc. | Transglutaminase originating from Crassostrea gigas |
EP0777726B1 (en) * | 1994-08-26 | 2006-06-07 | Novozymes A/S | Microbial transglutaminases, their production and use |
EP0871712B1 (en) * | 1995-01-19 | 2003-08-27 | Novozymes A/S | Transglutaminases from oomycetes |
JP3669390B2 (ja) * | 1995-02-09 | 2005-07-06 | 味の素株式会社 | バチルス属細菌由来のトランスグルタミナーゼ |
EP0889133B1 (en) * | 1997-07-04 | 2004-03-10 | Ajinomoto Co., Inc. | Process for producing microbial transglutaminase |
-
1998
- 1998-07-02 EP EP98112315A patent/EP0889133B1/en not_active Expired - Lifetime
- 1998-07-02 DE DE69822251T patent/DE69822251T2/de not_active Expired - Lifetime
- 1998-07-02 US US09/109,063 patent/US6013498A/en not_active Expired - Lifetime
- 1998-07-02 DK DK98112315T patent/DK0889133T3/da active
- 1998-07-03 CN CNB98103375XA patent/CN1151252C/zh not_active Expired - Lifetime
- 1998-07-03 CA CA002237041A patent/CA2237041A1/en not_active Abandoned
- 1998-07-06 BR BR9802403-5A patent/BR9802403A/pt not_active Application Discontinuation
-
1999
- 1999-11-24 US US09/448,310 patent/US6538122B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1151252C (zh) | 2004-05-26 |
DE69822251D1 (de) | 2004-04-15 |
DE69822251T2 (de) | 2005-01-27 |
EP0889133A3 (en) | 1999-09-08 |
EP0889133B1 (en) | 2004-03-10 |
CA2237041A1 (en) | 1999-01-04 |
US6013498A (en) | 2000-01-11 |
DK0889133T3 (da) | 2004-04-13 |
EP0889133A2 (en) | 1999-01-07 |
US6538122B1 (en) | 2003-03-25 |
CN1253177A (zh) | 2000-05-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |